刘志强 - 天津医科大学

个人简介

教育背景 1997.09-2002.07 滨州医学院，临床医学，学士 2002.09-2005.07 西南医科大学，生理学，硕士 2005.09-2008.07 北京大学，生物化学与分子生物学，博士工作经历 2015.09-今天津医科大学基础医学院，生理与病理生理学系，教授 2014.10-2015.09 美国德克萨斯州大学MD 安德森癌症中心，骨髓瘤与淋巴瘤系，讲师 2010.08-2014.10 美国德克萨斯州大学MD 安德森癌症中心，骨髓瘤与淋巴瘤系，博士后 2008.12-2010.08 美国德克萨斯州大学医学中心，病理学系，博士后荣誉奖励天津市中青年科技创新领军人才天津市生理学会秘书长

研究领域

多发性骨髓瘤

近期论文

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1.Geng Y, Liu J, Xie Y, Jiang H, Zuo K, Li T, Liu Z*. Trichostatin A promotes GLI1 degradation and P21 expression in multiple myeloma cells. Cancer Manag Res. 2018 Aug 28;10: 2905-2914. 2.Liu Z#, Lai K, Xie Y, He X, Zhou X. Gli2 Mediated Activation of Hedgehog Signaling Attenuates Acute Pancreatitis via Balancing Inflammatory Cytokines in Mice. Cell Physiol Biochem. 2018;48(1):120-130. 3.Li T, Zhang X, Jiang K, Liu J, Liu Z. Dural effects of oxidative stress on cardiomyogenesis via Gata4 transcription and protein ubiquitination. Cell Death Dis. 2018 Feb 14;9(2):246. 4.Yang J#, Liu Z#, Liu H, He J, Yang J, Lin P, Wang Q, Du J, Ma W, Yin Z, Davis E, Orlowski RZ, Hou J, Yi Q. C-reactive protein promotes bone destruction in human myeloma through the CD32-p38 MAPK-Twist axis. Sci Signal. 2017 Dec 12; 10(509). 5.Pang J, Shi Q, Liu Z, He J, Liu H, Lin P, Cui J, Yang J. Resistin induces multidrug resistance in myeloma by inhibiting cell death and upregulating ABC transporter expression. Heamatologica. 2017. 6.Liu H#, Liu Z#, Du J, He J, Lin P, Amini B, Starbuck MW, Novane N, Shah JJ, Davis RE, Hou J, Gagel RF, Yang J. Thymidine phosphorylase exerts complex effects on bone resorption and formation in myeloma. Sci Transl Med, 2016, 8 (353): 353ra113. 7.Liu Z#, Xu J#, He J, Liu H, Lin P, Wan X, Navone NM, Tong Q, Kwak LW, Orlowski RZ, Yang J.Mature adipocytes in bone marrow protect myeloma cells against chemotherapy through autophagy activation.. Oncotarget. 2015, 6(33): 34329-41. 8.Liu Z#, Xu J, He J, Zheng Y, Li H, Lu Y, Qian J, Lin P, Weber DM, Yang J, Yi Q. A Critical Role of Autocrine Sonic Hedgehog Signaling in Human CD138+ Myeloma Cell Survival and Drug Resistance. Blood. 2014, 124(13): 2061-71. 9.Liu Z#, Li T, Jiang K, Huang Q, Chen Y, Qian F. Induction of chemoresistance by all-trans retinoic acid via a noncanonical signaling in multiple myeloma cells. Plos One. 2014 Jan 9; 9(1): e85571. 10.Liu Z*, Li T, Reinhold MI, Naski MC*. MEK1 RSK2 contributes to Hedgehog signaling by stabilizing GLI2 transcription factor and inhibiting ubiquitination. Oncogene. 2014, 33(1): 65-73.