余秋景 - 天津医科大学

个人简介

教育背景 1999.09–2004.06，山东大学，预防，医学学士 2004.09–2011.06，中科院上海生命科学院营养所，生物化学与分子生物学，理学博士工作经历 2018.01-至今，天津医科大学基础医学院免疫系, 教授 2016.01-2017.12，上海交通大学附属上海市第一人民医院，临床转化研究院，细胞代谢所课题组副组长 (Co-PI) ，副研究员 2012.1-2015.12，美国宾夕法尼亚大学兽医学院，博士后

研究领域

代谢酶及其代谢产物在抗病毒免疫中的作用

近期论文

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1)Wang T#*, Yu Q#, Li J, Hu B, Zhao Q, Ma C, Huang W, Zhuo L, Fang H, Liao L, Chin Y.E, Jiang Y*. O-GlcNAcylation of fumarase maintains tumor growth under glucose deficiency. Nat Cell Biol. 2017 Jul;19(7):833-843. (Co-first Author) 2)Qian X, Li X, Cai Q, Zhang C, Yu Q, Jiang Y, Lee JH, Hawke D, Wang Y, Xia Y, Zheng Y, Jiang BH, Liu DX, Jiang T, Lu Z*. Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy. Mol Cell. 2017 Mar 2;65(5):917-931. 3)Katlinskaya YV, Katlinski KV, Yu Q, Ortiz A, Beiting DP, Brice A, Davar D, Sanders C, Kirkwood JM, Rui H, Xu X, Koumenis C, Diehl JA, Fuchs SY*. Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression. Cell Rep. 2016 Apr 5;15(1):171-180. 4)Katlinskaya YV, Carbone CJ, Yu Q, Fuchs SY*. Type 1 interferons contribute to the clearance of senescent cell. Cancer Biol Ther. 2015;16(8):1214-9. doi:10.1080/15384047.2015.1056419. 5)Yu Q#, Zhao B#, Gui J, Katlinski KV, Brice A, Gao Y, Li C, Kushner JA, Koumenis C, Diehl JA, Fuchs SY*. Type I interferons mediate pancreatic toxicities of PERK inhibition. Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15420-5. 6)Yu Q#, Katlinskaya YV#, Carbone CJ, Zhao B, Katlinski KV, Zheng H, Guha M, Li N,Chen Q, Yang T, Lengner CJ, Greenberg RA, Johnson FB, Fuchs SY*. DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function. Cell Rep. 2015 May 5;11(5):785-97. 7)Yu Q, Carbone CJ, Katlinskaya YV, Zheng H, Zheng K, Luo M, Wang PJ, Greenberg RA, Fuchs SY*. Type I interferon controls propagation of long interspersed element-1. J Biol Chem. 2015 Apr 17;290(16):10191-9. 8)Bhattacharya S, Katlinski KV, Reichert M, Takano S, Brice A, Zhao B, Yu Q, Zheng H, Carbone CJ, Katlinskaya YV, Leu NA, McCorkell KA, Srinivasan S, Girondo M, Rui H, May MJ, Avadhani NG, Rustgi AK, Fuchs SY*. Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury. EMBO Mol Med. 2014 Mar;6(3):384-97.