周东明 - 天津医科大学

个人简介

教育背景 1988.09 -1993.07 苏州医学院预防医学学士 1995.09 -1998.07 湖南医科大学流行病学硕士 1998.09 -2001.07 中南大学病原生物学博士工作经历 2019.03 -至今天津医科大学教授 2010.09 -2019.02 中国科学院上海巴斯德研究所研究员 2006.07 -2011.12 美国Wistar研究所疫苗研究中心研究员 2006.07 -2007.11 美国Wistar研究所疫苗载体中心主任 2004.08 -2006.06 美国Wistar研究所疫苗研究中心博士后 2002.11 -2004.07 美国宾夕法尼亚大学博士后 2002.01 -2002.10 美国田纳西大学健康科学中心博士后荣誉奖励 1．周东明，中国科学院分子病毒与免疫重点实验室2016年度创新奖，2016年 2．易新元，曾宪芳，蔡春，陈欲晓，陈利玉，周东明。日本血吸虫病疫苗候选分子的克隆与鉴定，湖南省科学技术进步奖，二等奖，2005年 3．易新元，曾宪芳，蔡春，陈欲晓，陈利玉，周东明，王敏，周金春，袁仁善，张冉。日本血吸虫病疫苗候选分子的克隆与鉴定，湖南省医学科技奖，一等奖，2004年

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1. Xu K, Song Y, Dai L, Zhang Y, Lu X, Xie Y, Zhang H, Cheng T, Wang Q, Huang Q, Bi Y, Liu WJ, Liu W, Li X, Qin C, Shi Y, Yan J, Zhou D*, Gao GF*. Recombinant Chimpanzee Adenovirus Vaccine AdC7-M/E Protects against Zika Virus Infection and Testis Damage. J Virol. 2018 Jan 3. pii: JVI.01722-17. doi: 10.1128/JVI.01722-17. 2. Dai W, Zhang C, Zhang X, Xiong P, Liu Q, Gong S, Geng L, Zhou D*, Huang Z*. A virus-like particle vaccine confers protection against enterovirus D68 lethal challenge in mice. Vaccine. 2017 Dec 30. pii: S0264-410X(17)31818-2. doi: 10.1016/j. vaccine.2017.12.057. 3. Guo J, Mondal M, Zhou D*. Development of novel vaccine vectors: chimpanzee adenoviral vectors. Hum Vaccin Immunother. 2018 Jan 4:0. doi: 10.1080/21645515.2017.1419108. 4. Wang CZ, Han HH, Tang XY, Zhou DM*, Wu C, Chen GR, He XP*, Tian H. Sialylglycan- Assembled Supra-dots for Ratiometric Probing and Blocking of Human-Infecting Influenza A Viruses. ACS Applied Materials & Interfaces. 2017, 9(30):25164-170. 5. Chen T, Li D, Song Y, Yang X, Liu Q, Jin X, Zhou D*, Huang Z*. A heterologous prime-boost Ebola virus vaccine regimen induces durable neutralizing antibody responses and prevent Ebola virus-like particle entry in mice. Antiviral Res. 2017 145: 54-59. 6. Tang X, Yang Y, Xia X, Zhang C, Yang X, Song Y, Dai X, Wang M, Zhou D*. Recombinant adenoviruses displaying matrix 2 ectodomain epitopes (M2e) on their fiber proteins as universal influenza vaccines. J. Virol. 2017, 91(7). pii: e02462-16.(Cover story). 7. Wang X, Fu W, Yuan S, Yang X, Song Y, Liu L, Chi Y, Cheng T, Xing M, Zhang Y, Zhang C, Yang Y, Zhu C, Zhang X, Xiong S,*, Xu J*, Zhou D*. Both haemagglutinin-specific antibody and T cell responses induced by a chimpanzee adenoviral vaccine confer protection against influenza H7N9 viral challenge. Sci Rep, 2017, 7(1):1854.doi: 10.1038/s41598-017-02019-1. 8. Song J, Tang X, Zhou DM※, Zhang W, James TD, He XP*, Tian H. A fluorgenic 2D glycosheet for the simultaneous identification of human- and avian-receptor specificity in influenza viruses. Mater. Horiz. 2017, doi: 10.1039/C6MH00571C. 9. Zhang C, Chi Y, Zhou D*, Development of Novel Vaccines against Infectious Diseases Based on Chimpanzee Adenoviral Vector, Methods Mol Biol. 2017; 1581:3-13. 10. Cheng T, Song Y, Zhang Y, Zhang C, Yin J, Chi Y, Zhou D*. A novel oncolytic adenovirus based on simian adenovirus serotype 24. Oncotarget 2017, 8(16): 26871-85. 11. He XP*, Zeng YL, Tang XY, Li N, Zhou DM*, Chen GR, Tian H*. Rapid identification of the receiptor-binding specificity of influenza A viruses by fluorogenic glycofoldmaers. Angew Chem Int Ed Engl. 2016, 55(45):13995-13999. 12. Xing M, Wang X, Chi Y, Zhou D*. Gene therapy for colorectal cancer using adenovirus-mediated full-length antibody, cetuximab, Oncotarget 2016, 7(19): 28262-72. 13. Tang X, Zhang H, Song Y, Zhou D*, Wang J*. Hemagglutinin-targeting artificial microRNAs expressed by adenovirus protect mice from different clades of H5N1 infection, Mol Ther Nucleic Acids 2016, doi: 10.1038/mtna.2016.25. 14. Cheng T, Wang X, Song Y, Tang X, Zhang C, Zhang H, Jin X*, Zhou D*. Chimpanzee adenovirus vector-based avian influenza vaccine completely protects mice against lethal challenge of H5N1. Vaccine. 2016, 34(41):4875-83. 15. Chi Y, Zhou D*, MicroRNA in colorectal carcinoma-from pathogenesis to therapy, J Exp Clin Cancer Res 2016, 35(1):43. doi: 10.1186/s13046-016-0320. 16. Zhang C, Zhou D*. Adenoviral vector-based strategies against infectious disease and cancer, Hum Vaccin Immunother 2016, 12(8):2064-2074. 17. Yang Y, Chi Y, Tang X, Ertl HC, Zhou D*, Rapid, Efficient, and Modular Generation of Adenoviral Vectors via Isothermal Assembly, Curr Protoc Mol Biol 2016, 113:16.26.1-16.26.18. 18. Song Y, Wang X, Zhang H, Tang X, Li M, Yao J, Jin X, Ertl HC, Zhou D*. Repeated Low-dose Influenza Virus Infection Causes Severe Disease in Mice: a Model for Vaccine Evaluation. J Virol. 2015; 89(15):7841-51. 19. Zhang H, Tang X, Zhu C, Song Y, Yin J, Xu J, Ertl HC, Zhou D*. Adenovirus-mediated artificial MicroRNAs targeting matrix or nucleoprotein genes protect mice against lethal influenza virus challenge. Gene Ther. 2015; 22(8):653-62. 20. Zhang C, Yang Y, Chi Y, Yin J, Yan L, Ku Z, Liu Q, Huang Z*, Zhou D*. Hexon-modified recombinant E1-deleted adenoviral vectors as bivalent vaccine carriers for Coxsackievirus A16 and Enterovirus 71.Vaccine. 2015; 33(39):5087-94.

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