个人简介
教育背景
1997/9 - 2002/7 内蒙古医科大学，临床医学，学士
2004/4 - 2006/3 日本神户大学，微生物免疫学，硕士
2006/4 - 2010/3 日本神户大学，分子生物学，博士
工作经历
2015/12-至今 天津医科大学，基础医学院，教授
2013/3 -2015/12 天津医科大学，基础医学院，副教授
2011/2 -2013/1 美国加州大学旧金山分校，博士后研究员
2010/4 -2011/2 日本神户大学，医学系研究科，特聘助理教授
近期论文
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1. Yoshizaki K*, Hu L*, Nguyen T, Sakai K, He B, Fong C, Yamada Y, Bikle DD, Oda Y. Ablation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair. 2014 Jun 20;9(6):e99991. doi: 10.1371 PLoS One 2014. (*co-first author)
2. Hu L*, Oda Y, Bikle.D D. Reciprocal Roles of VDR and b-catenin in the Regulation of Keratinocyte Proliferation and Differentiation. J Steroid Biochem Mol Biol. 144PA:237-241. 2014. (first author)
3. Man MQ, Hu L*, Elias PM. Herbal medicines prevent the development of atopic dermatitis by multiple mechanisms.Chin J Integr Med. 2016 Jan 6. (*corresponding author)
4. Ning Z, Song S, Miao L, Zhang P, Wang X, Liu J, Liang Y , Liu L, Zhang J, Hu L, Huo M, Zhou Q. High prevalence of vitamin D deficiency in urban health checkup population. Clin Nutr. 08;35(4):859-63.2016
5. Hu L*, Man H, Elias PM., Man MQ. Herbal medicines that benefit epidermal permeability barrier function. Dermatologica Sinica. 33:90-95; 2015 (*corresponding author)
6. Ren J*, Hu L* ,Yang J, Yang L, Gao F, Lu P, Fan M, Zhu Y, Liu J, Chen L, Gupta S, Yang X, Liu P. Novel T-cell epitopes on Schistosoma japonicum SjP40 protein and their preventive effect on allergic asthma in mice. Eur J Immunol. 2016 Feb 3. (*co-first author)
7. Yoshizaki K, Hu L, Nguyen T, Sakai K, Ishikawa M, Takahashi I, Fukumoto S, DenBesten PK, Bikle DD, Oda Y, Yamada Y. Mediator 1 contributes to enamel mineralization as a coactivator for Notch1 signaling and stimulates transcription of the alkaline phosphatase gene. J Biol Chem. 2017 Aug18;292(33):13531-13540
8. Hu L*, Man H, Elias PM., Man MQ. Herbal medicines that benefit epidermal permeability barrier function. Dermatologica Sinica. 33:90-95; 2015 (*corresponding author)
9. Oda Y*, Hu L*, Nguyen T, Fong C, Bikle DD. Combined Deletion of the Vitamin D Receptor and Calcium-Sensing Receptor Delays Wound Re-epithelialization. Endocrinology. 2017 Jun 1;158(6):1929-1938. (*co-first author)
10. Zhu X, Sun Y, Mu X, Guo P, Gao F, Zhang J, Zhu Y, Zhang X, Chen L, Ning Z, Bai Y, Ren J, Man M, Liu P, Hu L*. Phospholipase Cε deficiency delays the early stage of cutaneous wound healing and attenuates scar formation in mice. Biochem Biophys Res Commun. 2017 Feb 26;484 (1):144-151. (*corresponding author)
11. Hu L*, Mauro TM, Dang E, Man G, Zhang J, Lee D, Wang G, Feingold KR, Elias PM, Man MQ. Epidermal Dysfunction Leads to an Age-Associated Increase in Levels of Serum Inflammatory Cytokines. J Invest Dermatol. 2017 Jun;137(6):1277-1285. (corresponding author)
12. Li Z, Hu L*, Elias PM, Man MQ. Skin care products can aggravate epidermal function: studies in a murine model suggest a pathogenic role in sensitive skin. Contact Dermatitis. 2018 Feb;78(2):151-158. (*co-first author)
13. Oda Y*, Hu L*, Nguyen T, Fong C, Zhang J, Guo P, Bikle DD. Vitamin D receptor is required for proliferation, migration and differentiation of epidermal stem cells and progeny during cutaneous wound repair. J Invest Dermatol. 2018 May 19. (18)31971-7. (*co-first author)
14. Yao Y, Guo P, Feng X, Shen C, Huang J, Zhang J, Elias PM, Hu L*, Man MQ. A topical heparinoid-containing product improves epidermal permeability barrier homeostasis in mice. Exp Dermatol. 2019 Aug;28(8):956-960. (*corresponding author)
15. P Guo, J Huang, J Zhang, CMeng, S Zhang,Y Bai, Z Ning, Hu L*,The potential role of circRNA_004229 in hair/epidermal regulation after MED1 ablation in keratinocytes RSC Adv., 2019,9, 19095-19103 (*corresponding author)
学术兼职
天津医科大学党外知识分子联谊会副秘书长
中华医学会热带病与寄生虫学会分会委员
天津市医学会感染病学分会常务委员
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