章坤 - 天津医科大学

个人简介

教育背景 2007.09–2012.07 天津医科大学，医学检验，学士 2012.09–2017.07 天津医科大学，基础医学院，博士工作经历 2017.07 -至今天津医科大学，基础医学院，讲师

研究领域

非编码RNA和肝病

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1．Zhang K#, Han Y#, Hu Z#, Zhang Z#, Shao S, Yao Q, Zheng L, Wang J, Han X, Zhang Y, Chen T, Yao Z* Han T*, Hong W*, SCARNA10, a nuclear -retained long non-coding RNA, promotes liver fibrosis and serves as a potential biomarker, Theranostics, 2019; 9(12):3622-3638. 2. Han Y#, Zhang K #, Hong Y#, Wang J, Liu Q, Zhang Z, Xia X, Tang Y, Li T, Li L, Xue Y*, Hong W*, miR-342-3p promotes osteogenic differentiation via targeting ATF3, FEBS Lett, 2018, 592(24):4051-4065 3．Wang J#, Hong Y#, Shao S#, Zhang K *, Hong W*, FFAR1-and FFAR4-dependent activation of Hippo pathway mediates DHA-induced apoptosis of androgen-independent prostate cancer cells, Biochem Biophys Res Commun, 2018, 506(3):590-596 4．Han X#, Hong Y#, Zhang K*,TUG1 is involved in liver fibrosis and activation of HSCs by regulating miR-29b, Biochem Biophys Res Commun, 2018, 503(3):1394-1400 5．Zhang K#, Han X#, Zhang Z, Zheng L, Hu Z, Yao Q, Cui H, Shu G, Si M, Li C, Shi Z, Chen T, Han Y, Chang Y, Yao Z, Han T*, Hong W*. The liver-enriched lnc-LFAR1 promotes liver fibrosis by activating TGFβ and Notch pathways. Nature Communications, 2017 Jul 26; 8(1):144. 6．Shi Z#, Hong Y#, Zhang K#, Wang J, Zheng L, Zhang Z, Hu Z, Han X, Han Y, Chen T, Yao Q, Cui H, Hong W*. BAG-1M co-activates BACE1 transcription through NF-κB and accelerates Aβ production and memory deficit in Alzheimer's disease mouse model. BBA-Molecular Basis of Disease, 2017 Sep; 1863(9):2398-2407; 7．Zhang K#, Hu Z#, Qi H, Shi Z, Chang Y, Yao Q, Cui H, Zheng L, Han Y, Han X, Zhang Z, Chen T, Hong W*. G-protein-coupled receptors mediate ω-3 PUFAs-inhibited colorectal cancer by activating the Hippo pathway. Oncotarget. 2016 Sep6; 7(36):58315-58330. 8．Zhang K#, Chang Y#, Shi Z#, Han X, Han Y, Yao Q, Hu Z, Cui H, Zheng L, Han T*, Hong W*. ω-3 PUFAs ameliorate liver fibrosis and inhibit hepatic stellate cells proliferation and activation by promoting YAP/TAZ degradation. Scientific Reports. 2016 Jul20; 6:30029. 9．Zhang K, Qi HX, Hu ZM, Chang YN, Shi ZM, Han XH, Han YW, Zhang RX, Zhang Z, Chen T, Hong W*. YAP and TAZ Take Center Stage in Cancer. Biochemistry. 2015 Nov 3; 54(43):6555-66. 10．Zhang K, Shi ZM, Chang YN, Hu ZM, Qi HX, Hong W*. The ways of action of long non-coding RNAs in cytoplasm and nucleus. Gene. 2014 Aug 15;547(1):1-9.