洪伟 - 天津医科大学

个人简介

教育背景天津医科大学学士南开大学硕士德国卡尔斯鲁厄大学博士德国卡尔斯鲁厄｜吉森大学博士后工作经历 2007/9-至今天津医科大学教授

近期论文

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1、Zhang K, Han X, Zhang Z, Zheng L, Hu Z, Yao Q, Cui H, Shu G, Si M, Li C, Shi Z, Chen T, Han Y, Chang Y, Yao Z, Han T*, Hong W*. The liver-enriched lnc-LFAR1 promotes liver fibrosis by activating TGFβ and Notch pathways. Nature Communications, 2017 Jul 26; 8(1):144. 2、Zhang K, Han Y, Hu Z, Zhang Z, Shao S, Yao Q, Zheng L, Wang J, Han X, Zhang Y, Chen T, Yao Z*, Han T*, Hong W*. SCARNA10, a nuclear-retained long non-coding RNA, promotes liver fibrosis and serves as a potential biomarker. Theranostics. 2019 May 26;9(12):3622-3638. 3、Han Y, Hong Y, Li L, Li T, Zhang Z, Wang J, Xia H, Tang Y, Shi Z, Han X, Chen T, Liu Q, Zhang M, Zhang K, Hong W, Xue Y. A Transcriptome-Level Study Identifies Changing Expression Profiles for Ossification of the Ligamentum Flavum of the Spine. Mol Ther Nucleic Acids. 2018 Sep 7;12:872-883. 4、Han Y, Zhang K, Hong Y, Wang J, Liu Q, Zhang Z, Xia H, Tang Y, Li T, Li L, Xue Y*, Hong W*. miR-342-3p promotes osteogenic differentiation via targeting ATF3. FEBS Lett. 2018 Dec;592(24):4051-4065. 5、Shi Z, Hong Y, Zhang K, Wang J, Zheng L, Zhang Z, Hu Z, Han X, Han Y, Chen T, Yao Q, Cui H, Hong W*. BAG-1M co-activates BACE1 transcription through NF-κB and accelerates Aβ production and memory deficit in Alzheimer’s disease mouse model. BBA-Molecular Basis of Disease, 2017 Sep; 1863(9):2398-2407. 6、Shi Z, Chen T, Yao Q, Zheng L, Zhang Z, Wang J, Hu Z, Cui H, Han Y, Han X, Zhang K, Hong W*. The circular RNA ciRS-7 promotes APP and BACE1 degradation in an NF-κB-dependent manner. FEBS J. 2017 Apr;284(7):1096-1109. 7、Zhang K, Hu Z, Qi H, Shi Z, Chang Y, Yao Q, Cui H, Zheng L, Han Y, Han X, Zhang Z, Chen T, Hong W*. G-protein-coupled receptors mediate ω-3 PUFAs-inhibited colorectal cancer by activating the Hippo pathway. Oncotarget. 2016 Sep6; 7(36):58315-58330. 8、Zhang K, Chang Y, Shi Z, Han X, Han Y, Yao Q, Hu Z, Cui H, Zheng L, Han T*, Hong W*. ω-3 PUFAs ameliorate liver fibrosis and inhibit hepatic stellate cells proliferation and activation by promoting YAP/TAZ degradation. Scientific Reports. 2016 Jul20; 6:30029. 9、Shi ZM, Han YW, Han XH, Zhang K, Chang YN, Hu ZM, Qi HX, Chen T, Zhang Z, Hong W*. Upstream regulators and downstream effectors of NF-kB in Alzheimer’s disease, J Neurol Sci. 2016 Jul 15;366:127-34. 10、Chang YN, Zhang K, Hu ZM, Qi HX, Shi ZM, Han XH, Han YW, Hong W*. Hypoxia-regulated lncRNAs in cancer. Gene. 2016 Jan. 11、Zhang K, Qi HX, Hu ZM, Chang YN, Shi ZM, Han XH, Han YW, Zhang RX, Zhang Z, Chen T, Hong W*. YAP and TAZ Take Center Stage in Cancer. Biochemistry. 2015 Nov 3; 54(43):6555-66. 12、Hu Z, Qi H, Zhang R, Zhang K, Shi Z, Chang Y, Chen L, Esmaeili M, Baniahmad A, Hong W*. Docosahexaenoic acid inhibits the growth of hormone-dependent prostate cancer cells by promoting the degradation of the androgen receptor. Mol Med Rep，2015，12（3）： 3769-3774. 13、Wang C, Luo F, Zhou Y, Du X, Shi J, Zhao X, Xu Y, Zhu Y, Hong W*, Zhang J*. The therapeutic effects of docosahexaenoic acid on oestrogen/androgen-induced benign prostatic NSFC hyperplasia in rats. Experimental Cell Research，2015，S0014-4827（ 15）： 120-132. 14、Zhang K, Shi ZM, Chang YN, Hu ZM, Qi HX, Hong W*. The ways of action of long non-coding RNAs in cytoplasm and nucleus. Gene. 2014 Aug 15;547(1):1-9.