邓为民 - 天津医科大学

个人简介

教育背景 2000/9-2004/7，北京大学医学部，免疫学系，医学博士 1990/9-1993/7，天津医科大学，免疫学系，医学硕士 1985/9-1990/7，天津医科大学，临床医疗系，医学学士工作经历 2006/10 -至今，天津医科大学，基础医学院，教授，博士生导师 2013/1-2013/8，美国RUSH大学，交流合作 2009/10-2010/11，美国匹斯堡大学，国家留学基金委公派访问学者 2000/9-2004/7，北京大学医学部，攻读医学博士学位 2000/10-2006/9，天津医科大学，副教授 1995/10-2000/9，天津医科大学，讲师 1993/8-1995/9，天津医科大学，助教荣誉奖励 1. 2008年被评为“天津医科大学优秀教师” 2. 2007年被评为天津医科大学新世纪人才 3. Flk-1+间充质干细胞和肿瘤干细胞的分化机制及临床应用关键技术的研究。2006年，中华医学会科技奖，三等奖，第8完成人

研究领域

肿瘤微环境、肿瘤干细胞

近期论文

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1.Deng W, Gu X, Lu Y, Gu C, Zheng Y, Zhang Z, Chen L, Yao Z, Li LY. Down-modulation of TNFSF15 in ovarian cancer by VEGF and MCP-1 is a pre-requisite for tumor neovasculariza- tion. Angiogenesis. 2012 Mar;15(1):71-85. Epub 2011 Dec 31.（SCI，第一作者） 2.Xiulong Niu*, Wenxing Liu*, Yue Wang, Xiaomei Liu, Hongjian Zhang, Zhijun Li, Hongzhao Li, Yoichiro Iwakura, Weimin Deng. IL-17A exacerbates cisplatin-basedresistance of OVCA via upregulating the expression of ABCG2 and MDR1 throughGli1-mediated Hh signaling. Oncotarget, Advance Publications 2016（SCI收录，通讯作者） 3.Lu Y, Gu X, Chen L, Yao Z, Song J, Niu X, Xiang R, Cheng T, Qin Z, Deng W, Li LY. Interferon-γ produced by tumor-infiltrating NK cells and CD4+ T cells downregulates TNFSF15 expression in vascular endothelial cells. Angiogenesis. 2013 Oct 20. (SCI，并列通讯作者) 4.Niu XL, Wang Y, Yao Z, Duan H, Li Z, Liu W, Zhang H, *Deng WM.Autocrine interferon-γ may affect malignant behaviors and sensitivity to tamoxifen of MCF-7 via estrogen receptor β subtype. Oncol Rep. 2015 Dec;34(6):3120-30. （SCI收录，通讯作者）. Lu Y, Gu X, Chen L, Yao Z, Song J, Niu X, Xiang R, Cheng T, Qin Z, Deng W, Li LY. Interferon-γ produced by tumor-infiltrating NK cells and CD4+ T cells downregulates TNFSF15 expression in vascular endothelial cells. Angiogenesis. 2013 Oct 20. (SCI，并列通讯作者) 5.Du YR, Chen Y, Gao Y, Niu XL, Li YJ, Deng WM. Effects and mechanisms of anti-CD44 monoclonal antibody A3D8 on proliferation and apoptosis of sphere-forming cells with stemness from human ovarian cancer. Int J Gynecol Cancer. 2013 Oct;23(8):1367-75. （SCI，通讯作者) 6.GU Chao, DU YongRui, GAO Yan, YAO Zhi, GU Xin, ZHANG QiuYue, XU JingJing & DENG WeiMin. Anti-CD44 mAb remodels biological behaviors of spheroid cells with stemness from human ovarian cancer cell line SKOV-3. Chinese Science Bulletin. April 2012 Vol.57 No.11: 1288-1297.（SCI，通讯作者) 7.Deng W, Han Q, Liao L, Li C, Ge W, Zhao Z, You S, Deng H, Zhao RC. Allogeneic bone marrow-derived flk-1+Sca-1- mesenchymal stem cells leads to stable mixed chimerism and donor-specific tolerance. Exp Hematol. 2004 Sep; 32(9): 861-7. (SCI，共第一作者 ) 8.Deng W, Han Q, Liao L, Li C, Ge W, Zhao Z, You S, Deng H, Murad F, Zhao RC. Engrafted Bone Marrow-Derived Flk-1(+) Mesenchymal Stem Cells Regenerate Skin Tissue. Tissue Eng. 2005;11(1-2):110-119. (SCI，共第一作者 ) 9.Weimin Deng, Qin Han, Lianming Liao, Shengguo You, Hongye Deng and Robet CH Zhao. Effects of allogeneic bone marrow-derived mesenchymal stem cells on T and B lymphocyte from BXSB mice. DNA Cell Biol. 2005 Jul;24(7):458-63. (SCI，第一作者 ) 10.Liu WX1, Li ZJ, Niu XL, Yao Z, *Deng WM.The Role of T Helper 17 Cells and Other IL-17-Producing Cells in Bone Resorption and Remodeling. Int Rev Immunol. 2015;34(4):332-47. doi: 10.3109/08830185.2014.952414. Epub 2015 Mar 16. (SCI，通讯作者)