个人简介
教育背景
2004/09- 2007/07，天津医科大学，肿瘤分子病理学专业，博士
2001/09- 2004/07，天津医科大学，病理学专业，硕士
1994/09- 1999/07，天津医科大学，临床医学专业，学士
工作经历
2019/1-至今 天津医科大学，基础医学院副院长，生物化学与分子生物学系 教育部免疫微环境与疾病重点实验室，天津市表观遗传学重点实验室，教授 研究生导师
2009/10- 2018/12 天津医科大学，生物化学与分子生物学系，教育部免疫微环境与疾病重点实验室，天津市表观遗传学重点实验室，副教授，研究生导师
2009/12- 2011/01，美国德克萨斯大学西南医学中心，细胞生物学系，博士后
2006/07- 2009/09，天津医科大学，基础医学院，生物化学教研室，讲师
2004/11- 2006/07，天津医科大学，实验中心分子生物学研究室，讲师
1999/07- 2004/10，天津医科大学，实验中心分子生物学研究室，助教
荣誉奖励
2016年获天津医科大学教学优秀教师奖
2013年指导学生获天津市挑战杯科技作品大赛二等奖
2012年获中华医学会优秀论文三等奖
2012年被评为天津医科大学基础医学院优秀示范课教师
2011年获天津市优秀志愿者称号
2011年获天津医科大学挑战杯优秀指导教师，天津医科大学优秀共产党员，基础医学院优秀共产党员
2009年获国家留学基金委青年骨干教师计划资助
2008年获天津医科大学新世纪人才称号
2003年全国三好学生
近期论文
查看导师新发文章
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1. Liu R, Liu J, Wang S, Wang Y, Zhang T, Liu Y, Geng X, Wang F. Combined treatment with emodin and a telomerase inhibitor induces significant telomere damage/dysfunction and cell death.Cell Death Dis. 2019 Jul 11;10(7):527.
2. Ding X, Liu X, Wang F, Wang F, Geng X.Role of Senescence and Neuroprotective Effects of Telomerase in Neurodegenerative Diseases. Rejuvenation Res. 2019 Jul 18. doi: 10.1089/rej.2018.2115.
3. Zhang M, Wang B, Li T, Liu R, Xiao Y, Geng X, Li G, Liu Q, Price CM, Liu Y, Wang F.Mammalian CST averts replication failure by preventing G-quadruplex accumulation. Nucleic Acids Res. 2019 Jun 4;47(10):5243-5259.
4. Wang F, Cheng Y, Zhang C, Chang G, Geng X.A novel antisense oligonucleotide anchored on the intronic splicing enhancer of hTERT pre-mRNA inhibits telomerase activity and induces apoptosis in glioma cells. J Neurooncol. 2019 May;143(1):57-68.
5. Zhu Y, Liu X, Ding X, Wang F, Geng X. Telomere and its role in the aging pathways: telomere shortening, cell senescence and mitochondria dysfunction. Biogerontology. 2019 Feb;20(1):1-16. doi: 10.1007/s10522-018-9769-1.
6.Wang F, Zhang C, Hou S, Geng X. Synergistic Effects of Mesenchymal Stem Cell Transplantation and Repetitive Transcranial Magnetic Stimulation on Promoting Autophagy and Synaptic Plasticity in Vascular Dementia. J Gerontol A Biol Sci Med Sci. 2018 Sep 25. doi: 10.1093/gerona/gly221.
7. Yuan J, Liu Y, Wang J, Zhao Y, Li K, Jing Y, Zhang X, Liu Q, Geng X, Li G, Wang F. Long-term Persistent Organic Pollutants Exposure Induced Telomere Dysfunction and Senescence-Associated Secretary Phenotype. J Gerontol A Biol Sci Med Sci. 2018 Jul 9;73(8):1027-1035. doi: 10.1093/gerona/gly002.
8.Hou C, Wang F，Liu XW，Chang GM，Wang F，Geng X . Comprehensive Analysis of Interaction Networks of Telomerase Reverse Transcriptase with Multiple Bioinformatic Approaches: Deep Mining the Potential Functions of the Telomere and Telomerase. Rejuvenation Research, 2017,20(4):320-333.
9.Liu XW，Wang YC，Chang GM，Wang F，Wang F，Geng X . Alternative Splicing of hTERT Pre-mRNA: A Potential Strategy for the Regulation of Telomerase Activity. Int J Mol Sci, 2017, 18 (3). pii: E567.
10.Wang F, Chang GM, Yu Q, Geng X. The neuroprotection of repetitive transcranial magnetic stimulation pre-treatment in vascular dementia rats. J Mol Neurosci. 2015, 56(1): 198-204.
11.Wang F, Chang G, Geng X. NGF and TERT Co-Transfected BMSCs Improve the Restoration of Cognitive Impairment in Vascular Dementia Rats.PLoS One. 9 (6):e98774, 2014.
12.Wang F, Chang GM, Geng X. Bioinformatics analysis of exonic splicing enhancers (ESEs) for predicting potential regulatory elements of hTERT mRNA splicing. Eur Rev Med Pharmacol Sci. 18 (4): 526- 536, 2014.
13.Wang F, Geng Y, Zhang WM, Geng X. Identification of ZAG protein as a novel serologic biomarker candidate for liver cancer. Adv Mat Res. 340: 383-389, 2012.
14.Wang F, Geng Y, Zhang WM, Geng X. Bioinformatics analysis of zinc-alpha2-glycoprotein, a potential serological marker for hepatocellualr carcinoma. Adv Mat Res. 340: 390-396, 2012.
15.Bai R, Hu XL, Zhao LS, Geng X, Zhang WM. Analysis of DNMT1 gene polymorphisms in sporadic Wilms tumor. Adv Mat Res. 393-395: 593-596, 2012.
16.Wang Z, Xu J, Geng X, Zhang WM. Analysis of DNA methylation status of the promoter of human telomerase reverse transcriptase in gastric carcinogenesis.Arch Med Res. 41 (1): 1-6, 2010
17.Luo J, Li YN, Wang F, Zhang WM, Geng X. S-adenosylmethionine inhibits the growth of cancer cells by reversing the hypomethylation status of c-myc and H-ras in human gastric cancer and colon cancer. Int J Biol Sci. 6 (7): 784-795,2010
18.Li YG, Geng X. A meta-analysis on the association of HER-2 overexpression with prognosis in human osteosarcoma.Eur J Cancer Care (Engl). 19 (3) :313-316, 2010
19.Wang F, Geng X, Tao HY, Cheng Y. The restoration after repetitive transcranial magnetic stimulation treatment on cognitive ability of vascular dementia rats and its impacts on synaptic plasticity in hippocampal CA1 area.J MolNeurosci. 41 (1): 145-155, 2010
20.Peng XQ, Wang F, Geng X, Zhang WM. Current advances in tumor proteomics and candidate biomarkers for hepatic cancer. Exp Rev Proteomics. 2009, 6 (5), 551-561.
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