金美花 - 天津医科大学

个人简介

教育背景 1999年09月—2003年06月：延边大学，药学院，本科/学士 2003年09月—2005年08月：韩国岭南大学，药学院，研究生/硕士 2005年09月—2009年02月：韩国岭南大学，药学院，研究生/博士 2016年07月—今：天津医科大学，基础医学院，博士后工作经历 2011年01月—今：天津医科大学，药学院，副教授 2009年03月—2011年02月：韩国岭南大学，药学院，助教授荣誉奖励 (1)“131”创新型人才培养工程第二层次人选培养计划 (2) 天津市高校“优秀青年教师资助计划”

研究领域

肿瘤的免疫治疗、肿瘤发生与发展的分子机理

近期论文

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(1) Chen X, Ji N, Qin N, Tang SA, Wang R, Qiu Y, Duan H, Kong D, Jin M*. 1,6-O,O-Diacetylbritannilactone Inhibits Eotaxin-1 and ALOX15 Expression Through Inactivation of STAT6 in A549 Cells. Inflammation 2017, 40(6):1967-1974. (2) Chen Y, Ji N, Pan S, Zhang Z, Wang R, Qiu Y, Jin M* (共同通讯作者), Kong D*. Roburic Acid Suppresses NO and IL-6 Production via Targeting NF-kappaB and MAPK Pathway in RAW264.7 Cells. Inflammation 2017, 40(6):1959-1966. (3) Jin M (第一兼通讯), Kim S, Qin N, Chen X, Ji N, Tang SA, Kong D, Lee E, Duan H. 1,6-O,O-Diacetylbritannilactone suppresses activation of mast cell and airway hyper-responsiveness. Immunopharmacology and immunotoxicology 2017, 39(4): 173-179. (4) Wei X, Chen Y, Zhu H, Wu X, Yu Y, Kong D, Duan H*, Jin M* (共同通讯作者), Qin N*. Synthesis and anti-inflammatory activities of 1-O-acetylbritannilactone analogues. Phytochemistry letters 2017, 19: 248-253. (5) Chen X, Tang SA, Lee E, Qiu Y, Wang R, Duan HQ, Dan S, Jin M* (共同通讯作者), Kong D*. IVSE, isolated from Inula japonica,suppresses LPS-induced NO production via NF-kappaB and MAPK inactivation in RAW264.7 cells. Life sciences 2015, 124: 8-15. (6) Wang X, Tang SA, Wang R, Qiu Y, Jin M* (共同通讯作者), Kong D*. Inhibitory Effects of JEUD-38, a New Sesquiterpene Lactone from Inula japonica Thunb, on LPS-Induced iNOS Expression in RAW264.7 Cells. Inflammation 2015, 38(3): 941-948. (7) Jin M, Zhou Q, Lee E, Dan S, Duan HQ, Kong D*. AS252424, a PI3Kgamma inhibitor, downregulates inflammatory responsiveness in mouse bone marrow-derived mast cells. Inflammation 2014, 37(4): 1254-1260. (8) Tang SA, Zhu H, Qin N, Zhou JY, Lee E, Kong DX, Jin MH* (共同通讯作者), Duan HQ*. Anti-inflammatory terpenes from flowers of Inula japonica. Planta medica 2014, 80(7): 583-589 (9) Jin M, Zhao W, Zhang Y, Kobayashi M, Duan H*, Kong D*. Antiproliferative effect of aaptamine on human chronic myeloid leukemia K562 cells. International journal of molecular sciences 2011, 12(11): 7352-7359. (10) Jin M, Lu Y, Yang JH, Jo TH, Park YI, Lee CK, Park SJ, Son KH*, Chang HW*. Anti-inflammatory activity of 6-hydroxy-2,7-dimethoxy-1,4-henanthraquinone from tuberous roots of yam (Dioscorea batatas) through inhibition of prostaglandin D(2) and leukotriene C(4) production in mouse bone marrow-derived mast cells. Archives of pharmacal research 2011, 34(9): 1495-1501. (11) Jin M, Son KH*, Chang HW*. Luteolin-7-O-glucoside suppresses leukotriene C(4) production and degranulation by inhibiting the phosphorylation of mitogen activated protein kinases and phospholipase Cgamma1 in activated mouse bone marrow-derived mast cells. Biological & pharmaceutical bulletin 2011, 34(7): 1032-1036. (12) Lu Y, Jin M (共同第一作者), Park SJ, Son KH, Son JK*, Chang HW*. Batatasin I, a naturally occurring phenanthrene derivative, isolated from tuberous roots of Dioscorea batatas suppresses eicosanoids generation and degranulation in bone marrow derived-mast cells. Biological & pharmaceutical bulletin 2011, 34(7): 1021-1025.