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个人简介

教育背景 1993/9-1997/7 沈阳药科大学, 药物分析专业,本科 2000/9-2003/7 中国海洋大学, 药物化学专业,硕士 2003/9-2006/7 中国医学科学院/北京协和医学院, 生物医学工程,博士 工作经历 1997/7-2000/8,青岛海尔药业,助理工程师 2006/8-2010/10,天津医科大学,药学院,讲师 2010/11-2015/10,天津医科大学,药学院,副教授 2015/11-至今,天津医科大学,药学院,教授 2010/1-2012/12,天津医科大学,博士后 荣誉奖励 天津市高校中青年骨干创新人才 天津医科大学“十三五”卓越人才PI 天津医科大学“十一五”新世纪优秀人才 天津市2013年度自然科学奖二等奖

研究领域

纳米医学药剂学

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1.Guoyun Wan, Bowei Chen, Ling Li a, Dan Wang, Shurui Shi, Tao Zhang, Yue Wang, Lianyun Zhang, Yinsong Wang*. Nanoscaled red blood cells facilitate breast cancer treatment by combining photothermal/photodynamic therapy and chemotherapy. Biomaterials, 2018;155:25–40. SCI IF: 8.402. 2.Yuanyuan Liu, Linan Qiao, Sipei Zhang, Guoyun Wan, Bowei Chen, Ning Zhang*, Yinsong Wang*. Dual pH-responsive multifunctional nanoparticles for targeted treatment of breast cancer by combining immune- therapy and chemotherapy. Acta Biomater, DOI: 10.1016/j.actbio.2017.11.010. SCI IF: 6.319. 3.Yang Liu, Guoyun Wan, Huo Guo, Yuanyuan Liu, Ping Zhou, Hemei Wang, Dan Wang, Sipei Zhang, Yinsong Wang*, Ning Zhang*. A multifunctional nanoparticle system combines sonodynamic therapy and chemotherapy to treat hepatocellular carcinoma. Nano Research, 2017;10(3):834–855. SCI IF: 7.354. 4.Yue Wang, Guoyun Wan, Zhiyuan Li, Shurui Shi, Bowei Chen, Chunyu Li, Lianyun Zhan*, Yinsong Wang*. PEGylated doxorubicin nanoparticles mediated by HN-1 peptide for targeted treatment of oral squamous cell carcinoma. Int J Pharm, 2017;525:21–31. SCI IF: 3.649. 5.Xinghua Liu, Chunhui Gao, Junheng Gu, Wei Gao, Jingwei Fu, Yinsong Wang*, Xiaoying Yang*. Hyaluronic acid stabilized iodine-containing nanoparticles with Au nanoshell coating for X‑ray CT imaging and photothermal therapy of tumors. ACS Appl Mater Interfaces, 2016;8:27622−27631. SCI IF: 7.504. 6.Cong Zhang, Tong An, Dan Wang, Guoyun Wan, Mingming Zhang, Hemei Wang, Sipei Zhang, Rongshan Li, Xiaoying Yang, Yinsong Wang*. Stepwise pH-responsive nanoparticles containing charge-reversible pullulan-based shells and poly(β-amino ester)/poly(lactic-co-glycolic acid) cores as carriers of anticancer drugs for combination therapy on hepatocellular carcinoma. J Control Release, 2016;226:193–204. SCI IF: 7.786. 7.Hemei Wang, Guoyun Wan, Yuanyuan Liu, Bowei Chen, Ning Zhang*, Yinsong Wang*. Dual-responsive nanoparticles based on oxidized pullulan and a disulfide-containing poly(β-amino) ester for efficient delivery of genes and chemotherapeutic agents targeting hepatoma. Polym Chem, 2016;7:6340–6353. SCI IF: 5.375. 8.Tong An, Cong Zhang, Xue Han, Guoyun Wan, Dan Wang, Zhe Yang, Yue Wang, Lianyun Zhang, Wang Yinsong*. Hyaluronic acid-coated poly(b-amino) ester nanoparticles as carrier of doxorubicin for overcoming drug resistance in breast cancer cells. RSC Adv, 2016;6:38624–38636. SCI IF: 3.108. 9.Yan Wang, Yuanyuan Liu, Yang Liu, Wen Zhou, Hemei Wang, Guoyun Wan, Duxin Sun, Ning Zhang*, Yinsong Wang*. A polymeric prodrug of cisplatin based on pullulan for the targeted therapy against hepatocellular carcinoma. Int J Pharm, 2015;483:89–100. SCI IF: 3.649. 10.Ping Zhou, Tong An, Chuan Zhao, Yuan Li, Rongshan Li, Rui Yang, YinsongWang*, Xiujun Gao*. Lactosylated PLGA nanoparticles containing e-polylysine for the sustained release and liver-targeted delivery of the negatively charged proteins. Int J Pharm, 2015;478:633–643. SCI IF: 3.649. 11.Yu Ren, Ruirui Wang, Yang Liu, Huo Guo, Xuan Zhou, Xubo Yuan, Chaoyong Liu, Jianguo Tian, Haifang Yin, Yinsong Wang*, Ning Zhang*. A hematoporphyrin-based delivery system for drug resistance reversal and tumor ablation. Biomaterials, 2014;35:2460–2470. SCI IF: 8.402. 12.Yuanyuan Liu, Yan Wang, Cong Zhang, Ping Zhou, Yang Liu, Tong An, Duxin Sun, Ning Zhang*, Yinsong Wang*. Core-shell nanoparticles based on pullulan and poly(β-amino) ester for hepatoma-targeted codelivery of gene and chemotherapy agent. ACS Appl Mater Interfaces, 2014;6:18712–18720. SCI IF: 7.504. 13.Yinsong Wang*, Yang Liu, Yuanyuan Liu, Yan Wang, Jing Wu, Rongshan Li, Jinrong Yang, Ning Zhang*. pH-sensitive pullulan-based nanoparticles for intracellular drug delivery. Polym Chem, 2014;5:423–432. SCI IF: 5.375. 14.Huo Guo, Yuanyuan Liu, Yan Wang, Jing Wu, Xiaoying Yang, Rongshan Li, Yinsong Wang*, Ning Zhang*. pH-sensitive pullulan-based nanoparticle carrier for adriamycin to overcome drug-resistance of cancer cells. Carbohydr Polym, 2014;111:908–917. SCI IF: 4.811. 15.Yinsong Wang*, Hongli Chen, Yuanyuan Liu, Jing Wu, Ping Zhou, Yan Wang, Rongshan Li, Xiaoying Yang, Ning Zhang*. pH-sensitive pullulan-based nanoparticle carrier of methotrexate and combretastatin A4 for the combination therapy against hepatocellular carcinoma. Biomaterials, 2013;34:7181–7190. SCI IF: 8.402. 16.Yuanyuan Liu, Yi Luo, Jing Wu, Yinsong Wang*, Xiaoying Yang, Rui Yang, Baiqi Wang, Ning Zhang*. Graphene oxide can induce in vitro and in vivo mutagenesis. Scientific Reports, 2013;3: e3469. SCI IF: 4.259. 17.Jing Wu, Yinsong Wang*, Xiaoying Yang, Yuanyuan Liu, Jinrong Yang, Rui Yang, Ning Zhang*. Graphene oxide used as a carrier for adriamycin can reverse drug resistance in breast cancer cells. Nanotechnology, 2012;23:355101. SCI IF: 3.440. 18.Yinsong Wang, Xiaoying Yang, Jinrong Yang, Yumei Wang, Rou Chen, Jing Wu, Yuanyuan Liu, Ning Zhang*. Self-assembled nanoparticles of methotrexate conjugated O-carboxymethyl chitosan: preparation, characterization and drug release behavior in vitro. Carbohydr Polym, 2011;86:1665–1670. SCI IF: 4.811. 19.Yinsong Wang, Shaoli Tu, Rongshan Li, Xiaoying Yang, Lingrong Liu, Qiqing Zhang. Cholesterol succinyl chitosan anchored liposomes: preparation, characterization, physical stability, and drug release behavior. Nanomedicine- NBM, 2010;6:471–477. SCI IF: 5.720. 20.Yinsong Wang, Qian Jiang, Rongshan Li, Linglong Liu, Qiqing Zhang*, Yumei Wan, Jing Zhao. Self-assembled nanoparticles of cholesterol-modified O-carboxymethyl chitosan as a novel carrier for paclitaxel. Nanotechnology, 2008;19:145101. SCI IF: 3.440.

学术兼职

中国抗癌协会纳米肿瘤学专业委员会委员 中国生物材料学会纳米生物材料分会委员 天津药学会青年工作者委员会委员

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