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Yilin Zhao, Xue Wang, Ru Yao, Chengwen Li, Zelin Xu, Liming Zhang, Guifang Han,* Jingli Hou, Yangping Liu, Yuguang Song* Iron-catalyzed Alkene Trifluoromethylation in Tandem with Phenol Dearomatizing Spirocyclization: Regioselective Construction of the Trifluoromethylated Spirocarbocycles. Adv. Synth. Catal. 2021, DOI: 10.1002/adsc.202101201
Chengwen Li, Yilin Zhao, Jiaxin Zhou, Xue Wang, Jingli Hou, Yuguang Song, Wenjuan Liu and Guifang Han* Synthesis of Difluoroalkylated 2-Azaspiro[4.5]decanes Derivatives via Copper-Catalyzed Difluoroalkylation/ Dearomatization of N-Benzylacrylamides. Org. Biomol.Chem., 2020, 18, 8376–8380. (IF:3.412,一区)
Li Chengwen; Xue Li; Zhou Jiaxin; Zhao Yilin, Han Guifang*; Hou Jingli; Song Yuguang;Liu Yangping* Copper-Catalyzed Trifluoromethylation of Ynones Coupled with Dearomatizing Spirocyclization of Indoles: Access to CF3-Containing Spiro[cyclopentane-1,3’-indole], Org.Lett. 2020, 22, 3291−3296.
Xing Wang,# Chao Peng,# Ke He, Kaiyun Ji, Xiaoli Tan, Guifang Han,* Yanxia Liu,*Yangping Liu and Yuguang Song*. Intracellular delivery of liposome-encapsulated Finland trityl radicals for EPR oximetry. Analyst, 2020, 145, 4964–4971. (IF:3.978 ，一区)
Guifang Han, Lihua Qing, Meng Wu, Yuxiang Wang, Yuxiu Liu, Xueling Liu, Ziwen Wang,Jian Ding, Ling-hua Meng*, Qingmin Wang* Design, synthesis, and biological activity evaluation of (-)-6-O-desmethylantofine analogues as potent anti-cancer agents. Bioorganic &Medicinal Chemistry. 2019, 27, 3070–3081
Guifang Han, Li Xue, Lili Zhao, Tiaozhen Zhu, Jingli Hou, Yuguang Song*, Yangping Liu*Access to CF3‐Containing Cyclopentaquinolinone Derivatives from Indolyl‐ynones via Silver ‐Catalyzed One‐pot Reaction. Adv. Synth. Catal. 2019, 361, 678 –682.(VIP Paper)
Guifang Han, Linwei Chen, Qiang Wang, Meng Wu, Yuxiu Liu, and QingminWang*Design,Synthesis, and Antitobacco Mosaic Virus Activity of Water-Soluble Chiral Quaternary Ammonium Salts of Phenanthroindolizidines Alkaloids. J. Agric. Food Chem., 2018, 66 (4),780–788
Yuxiu Liu, Lihua Qing, Chuisong Meng, Jiajie Shi, Yan Yang, Ziwen Wang, Guifang Han, Yi Wang, Jian Ding, Ling-hua Meng*, and Qingmin Wang* 6-OH-Phenanthroquinolizidine Alkaloid and Its Derivatives Exert Potent Anticancer Activity by Delaying S Phase Progression.J. Med. Chem., 2017, 60 (7), 2764–2779 (IF: 6.259)
Guifang Han, Qiang Wang, Linwei Chen, Yuxiu Liu, and Qingmin Wang* Copper-Catalyzed Trifluoromethylation of Acrylamide Coupled with Dearomatization of Indole: Access to CF3‑Containing Spiro[indole-3,3'-pyrrolidine]. Adv. Synth. Catal. 2016, 358(4), 561-566. (IF: 5.646)
Guifang Han, Yuxiu Liu, and Qingmin Wang*. Copper-Catalyzed Intramolecular Trifluoromethylation of N‑Benzylacrylamides Coupled with Dearomatization: Access to CF3‑Containing 2‑Azaspiro[4.5]decanes. Org. Lett. 2014, 16, 3188−3191. (IF: 6.579)
Guifang Han, Qiang Wang, Yuxiu Liu, and Qingmin Wang* Copper-Mediated α-Trifluoromethylation of N-phenylcinnamamides Coupled with Dearomatization: Access to Trifluoromethylated 1-Azaspiro[4.5]decanes. Org. Lett. 2014, 16, 5914-5917. (IF: 6.579)
Guifang Han, Yuxiu Liu, and Qingmin Wang*. Total Synthesis of Phenanthroindolizidine Alkaloids through an Amidyl Radical Cascade/Rearrangement Reaction. Org. Lett. 2013, 15,5334−5337. (IF: 6.579)
Wenbo Liu, Jiangping Nie, Xiaoli Tan, Huiqiang Liu, Nannan Yu, Guifang Han, Yutian Zhu, Frederick A. Villamena, Yuguang Song, Jay L. Zweier,*and Yangping Liu*. Synthesis and Characterization of PEGylated Trityl Radicals: Effect of PEGylation on Physicochemical Properties. J. Org. Chem. 2017, 82, 588-596
Qiang Wang, Guifang Han, Yuxiu Liu, and Qingmin Wang*. Copper-Catalyzed Aryltrifluoromethylation of N-Phenylcinnamamides: Access to Trifluoromethylated 3,4-Dihydroquinolin-2(1H)-ones. Adv. Synth. Catal. 2015, 357, 2464–2468.
Meng Wu, Guifang Han, Chuisong Meng, Ziwen Wang, Yuxiu Liu, and Qingmin Wang*. Design, synthesis, and anti-tobacco mosaic virus (TMV) activity of glycoconjugates of phenanthroindolizidines alkaloids. Mol. Divers. 2014, 18, 25−37.
Meng Wu, Guifang Han, Ziwen Wang, Yuxiu Liu, and Qingmin Wang*. Synthesis and Antiviral Activities of Antofine Analogues with Different C-6 Substituent Groups. J. Agric. Food Chem. 2013, 61, 1030−1035.
Lei Liu, Yabin Wen, Kangning Liu, Liang Sun, Meng Wu, Guifang Han, Yaxin Lu*, Qingming Wang*, and Zheng Yin*. Optimization of on-line solid phase extraction and HPLC conditions using response surface methodology for determination of WM-5 in mouse plasma and its application to pharmacokinetic study. J. Chromatogr. B 2013, 923−924.
Ziwen Wang, Meng Wu, Yi Wang, Zheng Li, Lei Wang, Guifang Han, Fazhong Chen, Yuxiu Liu, Kailiang Wang, Ao Zhang*, Linghua Meng*, and Qingmin Wang*. Synthesis and SAR Studies of Phenanthroindolizidine and Phenanthroquinolizidine Alkaloids as Potent Anti-tumor Agents. Eur. J. Med. Chem. 2012, 51, 250−258.
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