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个人简介

教育背景 2004年9月—2008年7月:天津医科大学,药学院,药学(法学二学位),理学(法学)学士 2008年9月—2013年7月:天津医科大学,药学院,药理学,医学博士 工作经历 2018年1月—至今:天津医科大学,药学院,基础化学教研室,副教授 2013年7月—2017年12月:天津医科大学,药学院,基础化学教研室,讲师 2011年9月—2013年3月:美国Wake Forest University,化学系,联合培养博士研究生 荣誉奖励 1. 2018年,入选天津市和平区青年联合会第五届委员会委员 2. 2018年,入选天津医科大学首期卓越教师发展计划 3. 2018年,获第三节全国药理学青年教师教学基本功竞赛一等奖(英文组) 4. 2016年,2015-2016年度优秀班导师,天津医科大学 5. 2015年,天津医科大学学术年会优秀论文一等奖,天津医科大学 6. 2014年,入选天津市“131”创新人才培养工程(第三层次)

研究领域

新型铂类抗肿瘤药物的研发及作用机制研究

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. H Tian, X Qiao (co-first author), ZL Zhang, CZ Xie, QZ Li, JY Xu*. A high performance 2-hydroxynaphthalene Schiff base fluorescent chemosensor for Al3+ and its applications in imaging of living cells and zebrafish in vivo, Spectrochim. Acta A Mol. Biomol. Spectrosc., 2019, 207: 31-38. 2. ZL Zhang#, CL Zhao#, Q Chen, K Xu, X Qiao*, JY Xu*. Targeting RNA polymerase I transcription machinery in cancer cells by a novel monofunctional platinum-based agent, Eur. J. Med. Chem., 2018, 155: 434-444. 3. H Tian, X Qiao (co-first author), CZ Xie, Y Ouyang* and JY Xu*. Synthesis, characterization, and magnetochemical properties of two Mn-4 clusters derived from 2-pyridinecarboxaldehyde Schiff base ligands. J Coord Chem 2017; 70: 1207-1220. 4. WJ Lian, XT Wang, CZ Xie, H Tian, XQ Song, HT Pan, X Qiao* and JY Xu*. Mixed-ligand copper(II) Schiff base complexes: the role of the co-ligand in DNA binding, DNA cleavage, protein binding and cytotoxicity. Dalton Trans 2016; 45: 9073-9087. 5. X Qiao, S Ding, F Liu, GL Kucera, and U Bierbach*. Investigating the cellular fate of a DNA-targeted platinum-based anticancer agent by orthogonal double-click chemistry. J Biol Inorg Chem 2014; 19: 415-426. 6. X Qiao, ZY Ma, J Shao, WG Bao, JY Xu*, ZY Qiang and JS Lou*. Biological evaluation of a cytotoxic 2-substitued benzimidazole copper(II) complex: DNA damage, antiproliferation and apoptotic induction activity in human cervical cancer cells. Biometals 2014; 27: 155-172. 7. S Ding, X Qiao (co-first author), J Suryadi, GS Marrs, GL Kucera, and U Bierbach*. Using fluorescent post-labeling to probe the subcellular localization of DNA-targeted platinum. Angew Chem Int Ed2013; 52: 3350-3354. 8. X Qiao, AE Zeitany, MW Wright, AS Essader, KE Levine, GL Kucera and U Bierbach*. Analysis of the DNA damage produced by a platinum acridine antitumor agent and its effects in NCI-H460 lung cancer cells. Metallomics 2012; 4: 645-652 (Back cover paper). 9. X Qiao, ZY Ma, CZ Xie, F Xue, YW Zhang, JY Xu*, ZY Qiang*, JS Lou, GJ Chen and SP. Yan. Study on potential antitumor mechanism of a novel Schiff base copper(II) complex: synthesis, crystal structure, DNA binding, cytotoxicity and apoptosis induction activity. J Inorg Biochem 2011; 105: 728-737.

学术兼职

《天津药学》杂志英文终审编辑 Metallomics;Materials Science & Engineering C;Journal of Photochemistry & Photobiology, B: Biology;Journal of Coordination Chemistry;Cellular Physiology and Biochemistry期刊审稿人 中国化学会会员,中国药理学会会员

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