个人简介

Timothy J. Deming received a B.S. in Chemistry fom the University of California, Irvine in 1989, and graduated with a Ph.D. in Chemistry from the University of California, Berkeley, under Bruce Novak in 1993. After a NIH postdoctoral fellowship at the University of Massachusetts, Amherst with David Tirrell, he joined the faculty in the Materials Department at the University of California, Santa Barbara in 1995. Here he held a joint appointment in the Materials and Chemistry Departments where he was promoted to Associate Professor in 1999 and Full Professor in 2003. His appointment is now as the Chair of the Bioengineering Department at the University of California, Los Angeles. Current research interests include polypeptide synthesis, self-assembly of block copolypeptides, and biological activity of polypeptides, for which he has received young investigator awards from the National Science Foundation, the Office of Naval Research, The Arnold and Mabel Beckman Foundation, the Alfred P. Sloan Foundation, the Camille and Henry Dreyfus Foundation, the Materials Research Society, and the IUPAC Macromolecular Division.

研究领域

organic/Materials

Research in the Deming group is focused on synthesis, processing, characterization and evaluation of biological and biomimetic materials based on polypeptides. These materials are being studied since they can be prepared from renewable resources, they can be biocompatible and biodegradable, and possess unique self-assembling properties. We utilize innovative chemistry techniques to synthesize materials with properties that rival the complexity found in biological systems. The polymers are then processed into ordered assemblies, which are characterized for both nanoscale structure as well as biological function. This interdisciplinary approach stimulates innovations and ideas which direct this research into new, exciting areas.

近期论文

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Analogues of Poly(l-phosphoserine) via Living Polymerization of Phosphonate-Containing N-Carboxyanhydride Monomers Yakovlev, I.; Deming, T. J. ACS Macro Lett., 2014, 3, 378-381. Multimodal switching of conformation and solubility in homocysteine derived polypeptides Kramer, J. R.; Deming, T. J. J. Amer. Chem. Soc., 2014, 136, 5547–5550. Preparation and development of block copolypeptide vesicles and hydrogels for biological and medical applications Deming, T. J. WIREs Nanomed. Nanobiotechnol., 2014, 6, 283-297. Synthesis and self-assembly of well defined block copolypeptides via controlled NCA polymerization Deming, T. J. in Hierarchical Macromolecular Structures: 60 Years after the Staudinger Nobel Prize II Percec, V. (Ed.), Adv. Polymer Sci., 2013, 262, 1-37.