何华 - 中国药科大学

个人简介

何华，博士，副教授，硕士生导师。2013年毕业于中国药科大学药学院获博士学位。2015-2017年于美国北卡罗来纳大学教堂山分校从事博士后研究工作。

研究领域

药代动力学建模与仿真。近年专注于应用药动学-药效学(PK-PD)模型、生理药动学(PBPK)模型、群体药动学(PopPK)模型以及定量系统药理学(QSP)模型等方法定量研究药物与机体之间相互作用的规律

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

[1]. Hua He, Can Liu, Yun Wu, Xinyuan Zhang, Jianghong Fan, Yanguang Cao*. A Multiscale Physiologically-Based Pharmacokinetic Model for Doxorubicin to Explore its Mechanisms of Cytotoxicity and Cardiotoxicity in Human Physiological Contexts. Pharm Res. 2018 Jul 9;35(9):174. [2]. Hua He, Yanguang Cao*. Chemotherapeutic dosing implicated by pharmacodynamic modeling of in vitro cytotoxic data: a case study of paclitaxel. J Pharmacokinet Pharmacodyn. 2017 Oct;44(5):491-501. [3]. Haidong Wang, Xi Li, Wenting Zhang, Yao Liu, Shijun Wang, Xiaoquan Liu*, Hua He*. Mechanism-based pharmacokinetic-pharmacodynamic modeling of salvianolic acid A effects on plasma xanthine oxidase activity and uric acid levels in acute myocardial infarction rats. Xenobiotica. 2017;47(3):208-216. [4]. Haochen Liu, Xiaoting Zhou, Hao Jiang, Hua He*, Xiaoquan Liu*. A semi-mechanism approach based on MRI and proteomics for prediction of conversion from mild cognitive impairment to Alzheimer's disease. Sci Rep. 2016;6:26712. [5]. Haidong Wang, Hao Jiang, Haochen Liu, Xue Zhang, Guimei Ran, Hua He*, Xiaoquan Liu*. Modeling disease progression: angiotensin II indirectly inhibits nitric oxide production via ADMA accumulation in spontaneously hypertensive Rats. Front Physiol. 2016; 7: 555. [6]. Haochen Liu, Chunxiang Wei, Hua He*, Xiaoquan Liu*. Evaluating alzheimer's disease progression by modeling crosstalk network disruption. Front Neurosci. 2016;9:523.