个人简介
胡庆华,副教授,博士生导师。2002-2006年在南京大学匡亚明学院基础学科教学强化部学习获学士学位;2006-2011年在南京大学硕博连读并获博士学位,研究方向为抗炎免疫药理。目前主持国家自然科学基金面上项目1项(NSFC81773745)和企事业横向合作课题多项,参与国家自然科学基金项目1项(NSCF81373419),曾主持国家自然科学基金青年项目1项(NSFC81202573)和中央高校基本科研业务业务费培育项目1项(PY2014YX0004)。截至目前,已发表中、英文学术论文共26篇(SCI收录21篇,EI收录1篇,国内核心期刊4篇),其中第一作者或通讯作者论文16篇;作为第三发明人申请发明专利 1项并获得授权。
近期论文
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1. Ao GZ, Zhou MZ, Li YY, Li SN, Wang HN, Wan QW, Li HQ, Hu QH*. Discovery of novel curcumin derivatives targeting xanthine oxidase and urate transporter 1 as anti-hyperuricemic agents. Bioorg Med Chem25 (1): 166-174 (2017).
2. Hu QH, Zhou MZ, Zhu H, Lu G, Zheng DS, Li HQ, Hao K. (E)-2-(4-bromophenyl)-1-(2, 4-dihydroxyphenyl)ethanone oxime is a potential therapeutic agent for treatment of hyperuricemia through its dual inhibitory effects on XOD and URAT1. Biomed Pharmacother86: 88-94 (2017).
3. Wu H, Yuan YL, Chen YD, Lu G, Lan L, Yang ZL, Ji H, Hu QH*. Hypouricemic and nephroprotective effects of emodinol in oxonate-induced hyperuricemic mice are mediated by organic ion transporters and OIT3. Planta Med 82 (4): 289-297 (2016).
4. Hu QH, Wei B, Wei L, Hua K, Yu X, Li H, Ji H. Sodium tanshinone IIA sulfonate ameliorates ischemia-induced myocardial inflammation and lipid accumulation in Beagle dogs through NLRP3 inflammasome. Int J Cardiol 196, 183-192 (2015).
5. Li Q#,Hu QH#, Wang X, Zong Y, Zhao L, Xing J, Zhou J, Zhang H. Discovery of Novel 2-(piperidin-4-yl)-1H-benzo[d]imidazole Derivatives as Potential Anti-Inflammatory Agents. Chem Biol Drug Des86 (4), 509-516 (2015).
6. Hu QH, Zhu JX, Ji J, Wei LL, Miao MX, Ji H. Fructus Gardenia Extract ameliorates oxonate-induced hyperuricemia with renal dysfunction in mice by regulating organic ion transporters and mOIT3. Molecules18(8): 8976-8993 (2013).
7. Hu QH, Zhang X, Wang X, Jiao RQ, Kong LD. Quercetin regulates organic ion transporter and uromodulin expression and improves renal function in hyperuricemic mice. Eur J Nutr51 (5): 593-606 (2012).
8. Hu QH, Zhang X, Pan Y, Li YC, Kong LD. Allopurinol, quercetin and rutin ameliorate renal NLRP3 inflammasome activation and lipid accumulation in fructose-fed rats. Biochem Pharmacol84 (1): 113-125 (2012).