个人简介
丁杨,江苏南通人,中共党员,副教授,博导。2014年药剂学博士毕业后留校任教,现任药剂系副主任,药剂系党支部组织委员,研究生党支部教师书记,Asian Journal of Pharmaceutical Sciences(AJPS)青年编委,世界中医药学会联合会经皮给药专业委员会理事,国际控释协会CRS、美国药物科学家学会AAPS、中国药学会、江苏省药物研究与开发协会等会员。Adv Mater, Adv Drug Deliver Rev, Chem Sci, Small等杂志peer reviewer。
荣获江苏省科学技术进步二等奖(2/7,2018年),江苏省高校“青蓝工程”优秀青年骨干教师(2018年),江苏省微课竞赛二等奖(2018年),美国药学会AAPS学术研讨会优秀壁报、Travel Award奖(2019、2018年),江苏省普通高等学校本专科优秀毕业设计(论文)奖(2018、2016年),全国大学生药苑论坛创新成果、优秀壁报和优秀论文3个一等奖(2018年),全国高等学校药学类专业青年教师微课和教学能力大赛2个一等奖(2017年),岛津青年学者奖(2017年),卡乐康奖教金(2017年),中国药学会青年药剂学奖(2016年)等;副主编《药剂学实验与指导》第二版(上海交通大学出版社),参编2020版《中国药典》,国家级精品在线课程《工业药剂学》(2018年),2015版《国家执业药师》资格考试教材
研究领域
近年来重点关注恶性肿瘤、中枢神经系统疾病、心血管病变等重大疾病的病理特征和临床治疗瓶颈,准确把握“跨越病灶屏障,定位浓集给药”的治疗关键,依托智能药物载体的生物相容性、载药模式灵活性和药物递释可控性等优势,聚焦以下研究方向:1)微粒制剂研发与产业化,如(前体)脂质体,(纳米)混悬剂,脂质复合纳米药物的研究;2)脂蛋白纳米靶向载体及其给药系统的研究;3)新型生物医学材料及多功能纳米诊疗制剂的开发及应用。
近期论文
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1.Ruoning Wang, Yue Han, Bo Sun, Ziqiang Zhao, Yaw Opoku-Damoah, Hao Cheng, Huaqing Zhang, Jianping Zhou*, and Yang Ding*. Deep Tumor Penetrating Bioparticulates Inspired Burst Intracelluar Drug Release for Precision Chemo-Phototherapy. Small, 2018, 14(12): 1703110. (IF: 10.856)
2.Ruoning Wang, Chenshuang Zhang, Junsong Li, Jinyu Huang, Yaw Opoku- Damoahd Bo Sun, Jianping Zhou, Liuqing Di, Yang Ding*. Laser-triggered polymeric lipoproteins for precision tumor penetrating theranostics. Biomaterials, 2019, 221: 221 119413. (IF: 10.273)
3.Yue Han, Bixi Ding, Ziqiang Zhao, Huaqing Zhang, Bo Sun, Yuanpei Zhao, Lei Jiang, Jianping Zhou*, Yang Ding*. Immune lipoprotein nanostructures inspired relay drug delivery for amplifying antitumor efficiency. Biomaterials, 2018, 185: 205–218. (IF: 10.273)
4.Yang Ding #*, Yazhe Wang#, Yaw Opoku-Damoah, Cheng Wang, Lingjia Shen, Lifang Yin, Jianping Zhou*, Dual-functional bio-derived nanoparticulates for apoptotic antitumor therapy. Biomaterials, 2015, 72: 90-103. (IF: 8.387)
5.Yang Ding, Yazhe Wang, Jianping Zhou*, Xiaochen Gu, Wei Wang*, Congyan Liu, Xiuli Bao, Cheng Wang, Yuanru Li, Qiang Zhang. Direct cytosolic siRNA delivery by reconstituted high density lipoprotein for target-specific therapy of tumor angiogenesis. Biomaterials, 2014, 35 (25): 7214-7227. (IF: 8.557)
6.Yang Ding, Wang, Wei*; Feng, Meiqing; Wang, Yu; Zhou, Jianping*; Ding, Xuefang; Zhou, Xin; Liu, Congyan; Wang, Ruoning; Zhang, Qiang. A biomimetic nanovector-mediated targeted cholesterol-conjugated siRNA delivery for tumor gene therapy. Biomaterials, 2012, 33 (34): 8893-8905. (IF: 7.604)
7.Huaqing Zhang; Yuanpei, Zhao; Miao Yu; Ziqiang Zhao; Peixin Liu; Hao Cheng; Yi Ji; Yi Jin; Bo Sun; Jianping Zhou*; Yang Ding*. Reassembly of native components with donepezil to execute dual-missions in Alzheimer's disease therapy. Journal of Controlled Release, 2019, 296: 14-28. (IF:7.901)
8.Qiuling Dong, Huaqing Zhang, Yue Han, Aouameur Djamil, Hao Cheng, Zhiyuan Tang, Jianping Zhou*, Yang Ding*. Tumor environment differentiated “nanodepot” programmed for site-specific drug shuttling and combinative therapy on metastatic cancer. Journal of Controlled Release, 2018, 283: 59-75. (IF: 7.901)
9.RuoningWang, XiaochenGu, Jianping Zhou*, Lingjia Shen, Lifang Yin, Peiying Hua, Yang Ding*, Green design “bioinspired disassembly-reassembly strategy” applied for improved tumor-targeted anticancer drug delivery. Journal of Controlled Release, 2016, 235: 134-46. (IF: 7.786)
10.Lei Jiang#, Yang Ding #, Xialin Xue, Sensen Zhou, Cheng Li, Xiaoke Zhang, Xiqun Jiang*. Entrapping multifunctional dendritic nanoparticles into hydrogel for locally therapeutic delivery and synergetic immunochemotherapy. Nano Research, 2018, 11 (11): 6062-6073. (IF: 8.515)
11.Djamila Aouameur#, Hao Cheng#, Yaw Opoku-Damoah, Bo Sun, Qiuling Dong, Yue Han, Jianping Zhou*, and Yang Ding*. Stimuli-Responsive Gel-Micelles with Flexible Modulation of Drug Release for Maximized Antitumor Efficacy. Nano Research, 2018, 11 (8): 4245-4264. (IF: 8.515)
12.Yaw Opoku-Damoah, Assogba G. Assanhou, Mopa A. Sooro, Cynthia A. Baduweh, Chunmeng Sun*, and Yang Ding*. Functional Diagnostic and Therapeutic Nanoconstructs for Efficient Probing of Circulating Tumor Cells. ACS Appl. Mater. Interfaces, 2018, 10(17): 14231-14247. (IF: 8.456)
13.Yang Ding #*, Yue Han#, Ruoning Wang, Yazhe Wang, Cheng Chi, Ziqiang Zhao, Huaqing Zhang, Wei Wang*, Lifang Yin, Jianping Zhou*. Rerouting Native HDL to Predetermined Receptors for Improved Tumor-Targeted Gene Silencing Therapy. ACS Appl. Mater. Interfaces, 2017, 9(36): 30488–30501. (IF: 8.097)
14.Yaw Opoku-Damoah, Ruoning Wang, Jianping Zhou*, Yang Ding*, Versatile Nanosystem-Based Cancer Theranostics: Design Inspiration and Predetermined Routing. Theranostics, 2016, 6(7): 986-1003. (IF: 8.712)