何伟 - 中国药科大学

个人简介

何伟，药剂学博士，副教授，博士生导师，江苏省高校“青蓝工程”优秀青年骨干教师。2012年毕业于复旦大学并获药剂学博士学位，

研究领域

：（1）大分子药物（基因、蛋白、酶与多肽等）递送与心血管疾病治疗；（2）基于脂质体技术的药物共递送与重大炎症疾病联合治疗；（3）药物新剂型与新技术

近期论文

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Yaqi Lv, Chaoran Xu, Xiangmei Zhao, Chenshi Lin, Xin Yang, Xiaofei Xin, Li Zhang, Chao Qin, Xiaopeng Han, Lei Yang, He W*, Yin L*. Hybrid nanoplatform self-assembled from a CD44-targeted prodrug and smart liposomes for dual targeting of the tumor microenvironment and cancer cells. ACS Nano 2018, 12, 2, 1519-1536 2.Yaqi Lv, Xiangmei Zhao, Lidan Zhu, Sijia Li, Qingqing Xiao, He W*, Yin L*. Targeting Intracellular MMPs Efficiently Inhibits Tumor Metastasis and Angiogenesis. Theranostics, 2018; 8(10):2830-2845 3. Xin, X.; Pei, X.; Yang, X.; Lv, Y.; Zhang, L.; He W*, Yin L*. Rod-shaped active drug particles enable efficient and safe gene delivery. Advanced Science 2017 Sep 5;4(11):1700324 4.Xiaofei Xin, Xiaoqing Du, Yubing Wu, He W*, Yin L*. A Drug-Delivering-Drug Platform-Mediated Potent Protein Therapeutics via a Non-lysosomal Route, Theranostics, 2018; 8(13): 3474-3489. 5.Xiao Q, Zhu X, Yuan Y, Yin L*, He W*. A drug-delivering-drug strategy for combined treatment of metastatic breast cancer. Nanomedicine: Nanotechnology, Biology, and Medicine, 2018 doi:10.1016/j.nano.2018.06.012, article in press 6.Imran, He W*, Yin L*. A Smart Paclitaxel-Disulfiram Nanococrystals for Efficient MDR Reversal and Enhanced Apoptosis. Pharmaceutical Research, 2018, 35: 77. 7.Li Y, Wu Z, He W*, Qin C, Yao J, Zhou J, Yin L*. Globular Protein-Coated Paclitaxel Nanosuspensions: Interaction Mechanism, Direct Cytosolic Delivery and Significant Improvement in Pharmacokinetics. Molecular Pharmaceutics. 2015, 12.1485-1500 8.He, W., Wang, Y., Lv, Y., Xiao, Q., Ye, L., Cai, B., Qin, C., Han, X., Cai, T., Yin, L., 2017. Denatured protein stabilized drug nanoparticles: tunable drug state and penetration across the intestinal barrier. Journal of Materials Chemistry B 5, 1081-1097.