霍美蓉 - 中国药科大学

个人简介

霍美蓉，女，药剂学博士，中国药科大学教授，江苏省高校青蓝工程中青年学术带头人，主要从事药剂学教学及科研工作，主要研究方向为新剂型和新技术。近年来主持国家、省、部级项目6项，横向课题多项。获得中国药学会-石药青年药剂学奖、校级教学成果二等奖等。发表科研论文60余篇，其中第一及通讯作者SCI论文22篇（IF 92.736，外引次数>800）。申请16项专利，6项授权，参编教材或专著4部。 2001.9-2006.6 中国药科大学药剂学博士学位 2006.7-2010.5 中国药科大学药剂教研室讲师 2010.6-2015.12 中国药科大学药剂教研室副教授 2014.5-2015.5 美国北卡罗来纳大学教堂山分校访学 2016.1-2016.5 中国药科大学药剂教研室特聘研究员 2016.6-至今中国药科大学药剂教研室教授

研究领域

从事药剂学教学及科研工作，主要研究方向为新剂型和新技术

近期论文

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1、 Zhang XY, Yang CY, Zhou JP*, Huo MR* Somatostatin Receptor-Mediated Tumor-Targeting Nanocarriers Based on Octreotide-PEG Conjugated Nanographene Oxide for Combined Chemo and Photothermal Therapy, Small，2016 ，doi: 10.1002/smll.201600618. IF （IF= 8.315） 2、 Huo MR; Liu Y; Wang L; Yin TJ; Qin C; Xiao, YY; Yin LF; Liu JY*; Zhou JP* Redox-sensitive micelles based on O, N-hydroxyethyl chitosan-octylamine conjugates for triggered intracellular delivery of paclitaxel, Mol Pharm. 2016, 13(6):1750-62. (IF=4.342) 3、 Yin TJ, Cai H, Cui B, Wang L, Yin LF, Zhou JP* and Huo MR*, Biological evaluation of PEG modified nanosuspensions based on human serum albumin for tumor targeted delivery of paclitaxel, Eur J Pharm Sci, 2016 83(15) 79–87 (IF=3.773) 4、Yin TJ, Wang L, Yin LF, Zhou JP, Huo MR*. Co-delivery of hydrophobic paclitaxel and hydrophilic AURKA specific siRNA by redox-sensitive micelles for effective treatment of breast cancer. Biomaterials. 2015;61:10-25. （IF =8.557） 5、Yin TJ, Wang J, Yin LF, Shen LJ, Zhou JP*, Huo MR*.Redox-sensitive hyaluronic acid-paclitaxel conjugate micelles with high physical drug loading for efficient tumor therapy. Polym Chem. 2015,6, 8047-59 (IF=5.52) 6、 Yin T, Wu Q, Wang L, Yin L, Zhou J, Huo M*. Well-defined Redox-sensitive Polyethene glycol-Paclitaxel Prodrug Conjugate for Tumor Specific Delivery of Paclitaxel Using Octreotide for Tumor-targeting. Mol Pharm. 2015, 12 (8), 3020–31 （IF=4.384） 7、Yin TJ, Dong LH, Cui B, Wang L, Yin LF, Zhou JP* , Huo MR*, A toxic organic solvent-free technology for the preparation of PEGylated paclitaxel nanosuspension based on human serum albumin for effective cancer therapy, Int J Nanomed, 2015:10 ,7397-7412 ( IF=4.383) 8、Li J， Yin TJ，Zhou JP，Huo MR*，Biological evaluation of redox-sensitive micelles based on hyaluronic acid-deoxycholic acid conjugates for tumor-specific delivery of paclitaxel, Int J Pharm. 2015, 483(1-2):38-48 (IF=3.785) 9、 Huo MR，Zhu QN，Wu Q，Yin TJ，Wang Lei，Yin LF，Zhou JP，Somatostatin receptor-mediated specific delivery of paclitaxel prodrugs for efficient cancer therapy, J Pharm Sci, 2015;104(6): 2018-28 (IF=2.59) 10.、Huo MR, Zou AF, Yao CL, Zhang Y, Zhou JP, Wang J, Zhu QN, Li J, Zhang Q, Somatostatin receptor-mediated tumor-targeting drug delivery using octreotide-PEG-deoxycholic acid conjugate-modified N-deoxycholic acid-O, N-hydroxyethylation chitosan micelles, Biomaterials, 2012, 33 (27), 6393–6407（IF =8.557） 11、Li J, Huo MR*, Wang J, Zhou JP*, Jumah Masoud Mohammad, Zhang YL, Zhu QN, Ayman Yahia Waddad, Zhang Q, Redox-sensitive micelles self-assemble from amphiphilic hyaluronic acid-deoxycholic acid conjugates for targeted intracellular delivery of paclitaxel, Biomaterials, 2012,33(7), 2310-20（IF =8.557） 12、 Zou AF, Huo MR*, Zhang Y, Zhou JP*, Yin XQ, Yao CL, Zhang Q Octreotide-modified N-octyl-O, N-carboxymethyl chitosan micelles as potential carriers for targeted antitumor drug delivery, J Pharm Sci, 2012,101(2),627-40 (IF=3.055) 13、Zou AF, Chen Y, Huo MR*, Wang J, Zhou JP, Zhang Q. In vivo studies of octreotide-modified N-octyl-O, N-carboxymethyl chitosan micelles loaded with doxorubicin fortumor-targeted delivery. J Pharm Sci. 2013;102(1):126-35. (IF=3.007) 14、 Huo MR, Zhang Y, Zhou JP*, Zou AF, Li J. Formation, microstructure, biodistribution and absence of toxicity of polymeric micelles formed by N-octyl-N,O-carboxymethyl chitosan, Carbohydr Polymer, 2011, 83(4), 1959-69 (IF=3.628) 15、 Huo MR, Zhang Y, Zhou JP*, Zou AF, Yu D, Wu YP, Li J. Synthesis and characterization of low-toxic amphiphilic chitosan derivatives and their application as micelle carrier for antitumor drug. Int J Pharm. 2010, 15;394(1-2):162-73. (IF=3.35) 16、Zhang Y, Huo MR(co-first author), Zhou JP*, Zou AF, Li WZ, Yao CL, Xie SF. DDSolver: an add-in program for modeling and comparison of drug dissolution profiles. AAPS J.2010;12(3):263-71. (IF=5.086) 17、 Li H, Huo MR(co-first author), Zhou JP*, Dai YD, Deng YP, Shi XJ, Masoud J. Enhanced oral absorption of paclitaxel in N-deoxycholic acid-N, O-hydroxyethyl chitosan micellar system, J Pharm Sci. 2010; 99(11): 4543-53 (IF=3.055) 18、 Li WZ, Huo MR(co-first author), Zhou JP*, Zhou YQ, Hao BH, Liu T, Zhang Y. Super-short solid silicon microneedles for transdermal drug delivery applications. Int J Pharm. 2010;389(1-2):122-9. (IF=3.35) 19、Yong Zhang, Meirong Huo(co-first author), Jianping Zhou, PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel. Comput Methods Programs Biomed. 2010, 99(3):306-14 (IF=1.516)