个人简介
孙敏捷,女,1977年出生,博士、教授、博士生导师。中国药科大学药学院党委委员,药剂系主任,江苏省中医药学会新药研究与开发专委会常委,江苏省药物研究与开发协会医疗器械与药学装备专委会委员,白求恩医学专家委员会青年专家委员会委员。
2005年加入中国药科大学药剂教研室工作。1999年获得南京大学高分子科学与工程学士学位;2005年获得南京大学生物化学与分子生物学硕士学位;2013年获得中国药科大学药剂学博士学位。曾于美国内布拉斯加大学医学中心高级访问学者(2013-2014),入选江苏省“六大人才高峰”高层次人才(2015),获得江苏省自然科学基金“杰出青年基金”(2017),教育部高等学校科学研究优秀成果一等奖(2017),入选江苏省“333高层次人才培养工程”第三层次培养对象(2018),并获得中国药科大学“复星奖教金”、“岛津青年学者”、“博瑞教学奖”等荣誉。
研究领域
生物药物/载体递送研究;智能/多功能纳米制剂技术研究;高端制剂研发与产业化
近期论文
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1.Yang, X.; Yang, Y.; Gao, F.; Wei, J.; Qian, C.*; Sun, M.*, Biomimetic Hybrid Nanozymes with Self-Supplied H+ and Accelerated O2 Generation for Enhanced Starvation and Photodynamic Therapy against Hypoxic Tumors. Nano Letters 2019, 19 (7), 4334-42.
2.Zhou, Z.; Liu, Y.; Zhang, M.; Li, C.; Yang, R.; Li, J.; Qian, C.; Sun, M.*, Size Switchable Nanoclusters Fueled by Extracellular ATP for Promoting the Deep Penetration and MRI Guided Tumor Photothermal Therapy. Advanced Functional Materials2019, 1904144, 1-12.
3.Li, J.; Zhang, C.; Gong, S.; Li, X.; Yu, M.; Qian, C.; Qiao, H.; Sun, M.*, A nanoscale photothermal agent based on a metal-organic coordination polymer as a drug-loading framework for effective combination therapy. Acta Biomaterialia 2019, 94, 435-446.
4.Zhang, Q.; Zhou, Z.; Li, C.; Wu, P.; Sun, M.*, pH-Switchable Coordinative Micelles for Enhancing Cellular Transfection of Biocompatible Polycations. ACS Applied Materials &Interfaces 2019, 11 (23), 20689-698.
5.Chen, G.; Wang, Y.; Wu, P.; Zhou, Y.; Yu, F.; Zhu, C.; Li, Z.; Hang, Y.; Wang, K.; Li, J.; Sun, M.*, Oupicky, D.*, Reversibly Stabilized Polycation Nanoparticles for Combination Treatment of Early- and Late-Stage Metastatic Breast Cancer. ACS Nano 2018, 12 (7), 6620-36.
6.Li, H.; Yang, X.; Gao, F.; Qian, C.; Li, C.; Oupicky, D.; Sun, M.*, Bioreduction-ruptured nanogel for switch on/off release of Bcl2 siRNA in breast tumor therapy. Journal of Controlled Release2018, 292,78-90.
7.Zhou, Z.; Li, C.; Zhang, M.; Zhang, Q.; Qian, C.; Oupicky, D.; Sun, M.*, Charge and Assembly Reversible Micelles Fueled by Intracellular ATP for Improved siRNA Transfection. ACS Applied Materials & Interfaces 2018, 10 (38), 32026-037.
8.Li, H.; Zhou, Z.; Zhang, F.; Guo, Y.; Yang, X.; Jiang, H.; Tan, F.; Oupicky, D.; Sun, M.*, A networked swellable dextrin nanogels loading Bcl2 siRNA for melanoma tumor therapy. Nano Research 2018, 11(9),4627-42.
9.Zhou, Z.; Zhang, Q.; Zhang, M.; Li, H.; Chen, G.; Qian, C.; Oupicky, D.; Sun, M.*, ATP-activated decrosslinking and charge-reversal vectors for siRNA delivery and cancer therapy. Theranostics 2018, 8 (17), 4604-19.
10.Li,H.; Yang. X.; Zhou, Z.; Wang, K.; Li, C.; Qiao, H.; Oupicky, D.; Sun, M.*, Near-infrared light-triggered drug release from a multiple lipid carrier complex using an all-in-one strategy. Journal of Controlled Release 2017, 261, 126-137.