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个人简介

教育经历 2011/09-2016/06, 中国药科大学,药学院,博士(硕博连读) 2007/09-2011/06, 中国药科大学,药学院,学士 工作经历 2019/07 至今, 中国药科大学, 药学院, 副教授 2016/07-2019/06, 中国药科大学, 药学院, 讲师

研究领域

(1) 基于肿瘤细胞特定的氨基酸代谢特征开展小分子靶向药物及探针的研究 (2) 肿瘤及炎症相关丝氨酸/苏氨酸激酶抑制剂的发现研究 (3) 小分子免疫调控剂创新药物的研发与产业化

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Yucheng Tian, Kang Liu, Ruoyi Liu, Zhixia Qiu, Yifan Xu, Wei Wei, Xi Xu, Jubo Wang, Hong Ding, Zhiyu Li*; Jinlei Bian*, Discovery of Potent Small-Molecule USP8 Inhibitors for the Treatment of Breast Cancer through Regulating ERα Expression. Journal of Medicinal Chemistry, 2022, 65: 8914-8932. (IF: 8.039) Xi Xu#; Jubo Wang#; Min Wang; Xinyu Yuan; Lei Li; Chao Zhang; Huidan Huang*; Tian Jing; Chenchen Wang; Chao Tong; Liwen Zhou; Ying Meng; Pengfei Xu; Junping Kou; Zhixia Qiu; Zhiyu Li*; Jinlei Bian*, Structure-Enabled Discovery of Novel Macrocyclic Inhibitors Targeting Glutaminase 1 Allosteric Binding Site, Journal of Medicinal Chemistry, 2021, 64: 4588-4611. (IF: 8.039) Zhen Qin#; Bin Dong#; Renbing Wang; Dechun Huang; Jubo Wang*; Xi Feng; Jinlei Bian*; Zhiyu Li*, Preparing anti-SARS-CoV-2 agent EIDD-2801 by a practical and scalable approach, and quick evaluation via machine learning, Acta Pharmaceutica Sinica B, 2021, 11: 3678-3682. (IF: 14.903) Zhen Qin; Lian Qin; Xi Feng; Zhiyu Li*; Jinlei Bian*, Development of Cdc2-like Kinase 2 Inhibitors: Achievements and Future Directions. Journal of Medicinal Chemistry, 2021, 64: 13191-13211. (IF: 8.039) Yucheng Tian#; Jubo Wang#; Xinying Cheng; Kang Liu; Tizhi Wu; Xiaqiu Qiu; Zijian Kuang; Zhiyu Li*; Jinlei Bian*, Microwave-assisted unprotected Sonogashira reaction in water for the synthesis of polysubstituted aromatic acetylene compounds, Green Chemistry, 2020, 22:1338-1344. (IF: 11.034) Xi Feng; Dongdong Liao; Dongyu Liu; An Ping; Zhiyu Li*; Jinlei Bian*, Development of Indoleamine 2,3-Dioxygenase 1 Inhibitors for Cancer Therapy and Beyond: A Recent Perspective, Journal of Medicinal Chemistry, 2020, 63: 15115-15139. (IF: 8.039) Xi Xu; Zijian Kuang; Jie Han; Ying Meng; Lei Li; Hongyu Luan; Pengfei Xu; Jubo Wang; Cheng Luo; Hong Ding; Zhiyu Li*; Jinlei Bian*, Development and Characterization of a Fluorescent Probe for GLS1 and the Application for High-Throughput Screening of Allosteric Inhibitors, Journal of Medicinal Chemistry, 2019, 62: 9642-9657. (IF: 8.039) Tizhi Wu, Zhen Qin, Yucheng Tian, Jubo Wang, Chenxi Xu, Zhiyu Li* and Jinlei Bian*. Recent Developments in the Biology and Medicinal Chemistry of CDK9 Inhibitors: An Update. Journal of Medicinal Chemistry, 2019, 62: 9642−9657. (IF: 8.039) Xi Xu, Ying Meng, Lei Li, Pengfei Xu, Jubo Wang, Zhiyu Li,* and Jinlei Bian*.Overview of the Development of Glutaminase Inhibitors: Achievements and Future Directions. Journal of Medicinal Chemistry, 2019, 62: 1096−1115. (IF: 8.039) Qianming Du#; Xi Feng#; Yinuo Wang; Xi Xu; Yan Zhang; Xinliang Qu; Zhiyu Li*; Jinlei Bian*, Discovery of phosphonamidate IDO1 inhibitors for the treatment of non-small cell lung cancer, European Journal of Medicinal Chemistry, 2019, 182: 111629. (IF: 7.088).

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