个人简介
王鹏,男,副教授,博士生导师。中国药科大学工学院生物医学工程教研室。主要从事小分子荧光探针在肿瘤早期诊断及诊疗中的应用、靶向抗肿瘤药物分子的设计与活性研究、基于小分子荧光探针的智控载药系统等方面的研究。主持国家自然科学基金、江苏省自然科学基金、中央高校基本科研项目以及校级项目多项。入选江苏省青蓝工程优秀青年骨干教师(2018)、江苏省双创计划“科技副总”(2018)等计划。以第一作者或通讯作者在Small、Biosensors and Bioectronics、ACS Applied Materials & Interfaces、Sensors and Actuators B: Chemical、Analytica Chimica Acta、European Journal of Medicinal Chemistry、Molecular Pharmaceutics等学术期刊发表SCI学术论文四十余篇;申请中国发明专利6项,授权4项;参与研发的抗肿瘤1.1类新药于2017年3月进入I期临床试验。
主要学习及工作经历:
2014.7—至今中国药科大学工学院
2018.10—2019.10 美国哈佛医学院/麻省总医院Martinos Center 访问学者
2011.3—2014.6 东南大学生物医学工程专业 博士
2005.9—2008.6 中国药科大学药学院药物化学专业 硕士
2001.9—2005.6 山东大学药学院药学专业本科
研究领域
小分子荧光探针在肿瘤早期诊断及诊疗中的应用
靶向抗肿瘤药物分子的设计与活性研究
基于小分子荧光探针的智控载药系统
近期论文
查看导师新发文章
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Han Wang, Zhaohui Wang, Yongkuan Li, Tian Xu, Qi Zhang, Man Yang, Peng Wang,* Yueqing Gu*.A Novel Theranostic Nanoprobe for In Vivo SingletOxygen Detection and Real-Time Dose–Effect Relationship Monitoring in Photodynamic Therapy, Small 2019, 1902185.
Han Wang, Yongkuan Li, Man Yang, Peng Wang,* and Yueqing Gu*, FRET-Based Upconversion Nanoprobe Sensitized by Nd3+ for theRatiometric Detection of Hydrogen Peroxide in Vivo, ACS Appl. Mater. Interfaces 2019, 11, 7441−7449.
Yang Liu, Min Ji,*, Peng Wang*, Recent Advances in Small Copper Sulfide Nanoparticles for Molecular Imaging and Tumor Therapy, Mol. Pharmaceutics 2019, 16, 3322−3332.
Lili Xia, Fang Hu, Jinxin Huang, Nan Li, Yueqing Gu*, Peng Wang*, A fluorescent turn-on probe for nitroreductase imaging in living cellsand tissues under hypoxia conditions, Sensors and Actuators B, 2018, 268: 70–76.
Yuxiang Ma, Ying Zhao, Lili Xia, Jinxin Huang, Yueqing Gu, Peng Wang*, A novel one- and two-photon fluorescent probe induced by light for selective imaging of Cys in living cells and tissues, Analytica Chimica Acta, 2018, 1035: 161-167.
Wang Peng*,Wang Qianqian,Huang Jinxin,Li Nan,Gu Yueqing *,A dual-site fluorescent probe for direct and highly selective detection of cysteine and its application in living cells,Biosensors and Bioelectronics,2017,92:583~588.
Huang Jinxin,Li Nan,Wang Qianqian,Gu Yueqing*,Wang Peng*,A lysosome-targetable and two-photon fluorescent probe for imaging endogenous β-galactosidase in living ovarian cancer cells,Sensors and Actuators B: Chemical,2017,246:833~839.
Wang Peng,Wang Ke,Gu Yueqing*,A highly selective fluorescent turn-on NIR probe for the bioimaging of hydrogen peroxide in vitro and in vivo,Sensors and Actuators B: Chemical,2016,228:174~179.
Wang Peng*,Huang Jinxin,Wang Ke,Gu Yueqing*,New Palbociclib analogues modified at the terminal piperazine ring and their anticancer activities,European Journal of Medicinal Chemistry,2016,122:546~556.
Wang Peng*,Cai Jin,Chen Junqing,Ji Min*,Synthesis and anticancer activities of ceritinib analogs modified in the terminal piperidine ring,European Journal of Medicinal Chemistry,2015,93:1~8.