江峰 - 中国药科大学

个人简介

1999.9-2003.7 武汉工程大学化工与制药学院制药工程专业，学士； 2004.9-2009.7 华南理工大学化学与化工学院化学工程专业，博士（硕博连读）； 2009.7-至今中国药科大学制药工程教研室任教； 2015.3-2016.3 美国加州大学洛杉矶分校（UCLA）化学与生物化学系Michael E. Jung教授实验室访问学者

研究领域

1. 基于多样性导向合成方法，围绕生物活性类天然产物进行分子优化、虚拟筛选和体内外活性评价，推进具有临床应用潜力的自主新药研发；2. 探索“绿色化学合成技术”在药物合成中的应用，发展药物绿色合成新方法，开发药物绿色制造新工艺。近年主要从事抗肿瘤类天然产物分子设计、合成与构效关系，多肽固相合成与纯化等方面的研究工作。

近期论文

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Yuanyuan Lu, Yuru Yan, Linlin Wang, Xiaobing Wang, Jing Gao, Tao Xi, Zhixiang Wang, Feng Jiang*. Design, facile synthesis and biological evaluations of novel pyrano[3,2-a]phenazine hybrid molecules as antitumor agents. European Journal of Medicinal Chemistry. 2017, 127, 928-943. Yuanyuan Lu*, Linlin Wang, Xiaobing Wang, Tao Xi, Jianmin Liao, Zhixiang Wang, Feng Jiang*. Design, combinatorial synthesis and biological evaluations of novel 3-amino-1′-((1-aryl-1H-1,2,3-triazol-5-yl)methyl)-2′-oxospiro[benzo[a] pyrano[2,3-c]phenazine-1,3′-indoline]-2-carbonitrile antitumor hybrid molecules. European Journal of Medicinal Chemistry. 2017, 135, 125-141. Quantitative Design of Seed Load Based on model identification of nucleation and crystal growth stages without transmittance data. Hongliang Qian, Lin Dai, Feng Jiang, Yiqiang Shi, Zhixiang Wang, Wei Liu*, Dechun Huang*, Wei Chen. Powder Technology. 2018, 335, 11-17. Jing Gao, Ming Chen, Xue Tong, He Zhu, Hongbin Yan, Daichun Liu, Wanjing Li, Shengyu Qi, Dake Xiao, Yongzhi Wang, Yuanyuan Lu, Feng Jiang*. Synthesis, antitumor Activity, and structure-activity relationship of some benzo[a]pyrano[2,3-c]phenazine derivatives. Combinatorial Chemistry & High Throughput Screening, 2015, 18(10): 960-974. Feng Jiang, Lin Dai, Yiqiang Shi, Zhixiang Wang*. A three-dimensional chiral crystal structure constructed from a chiral triazolate ligand showing an SrSi2 topology: poly[bis(μ3-3,5-diethyl-1,2,4-triazolato-κ3N1:N2:N4)trisilver nitrate]. Acta Crystallographica, Section C: Crystal Structure Communications.2013. C69, 1485-1487. Feng Jiang, Yun Ling, Jinqing Qu*, Huanqin Chen. Synthesis and crystal structure of a novel chiral 1-methylpropargyl ester carrying azobenzene moiety. Chinese Journal of Structural Chemistry. 2010. 29(1): 146-150. Feng Jiang, Jinqing Qu*, Huanqin Chen. Synthesis and properties of polyacetylenes containing carbazole and amino acid moieties. Chinese Journal of Polymer Science. 2009. 27(6): 789-796. Feng Jiang, Jinqing Qu*, Huanqin Chen. Synthesis and characterization of poly(chiral methylpropargyl esters) carrying azobenzene moieties. Chinese Journal of Chemistry. 2009. 27(10): 2079-2084. Jinqing Qu*, Feng Jiang, Huanqin Chen, Sanda Fumio, Masuda Toshio. Synthesis and photoisomerization of poly(1-methylpropargyl ester)s carrying azobenzene moieties. Journal of Polymer Science: Part A: Polymer Chemistry. 2009. 47(18): 4749-4761. Jinqing Qu*, Feng Jiang, Huanqin Chen, Masuda Toshio. Synthesis and chiroptical properties of poly(methylpropargyl ester)s carrying ferrocene moieties. Journal of Macromolecular Science, Part A: Pure and Applied Chemistry. 2009. 46(2): 131-135.