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个人简介

张石柱,男,山东烟台人。2010年毕业于重庆大学获理学博士学位。博士期间(2008. 09-2010. 09),受国家留学基金委的资助,以联合培养博士生的身份到美国佛罗里达大学细胞科学和微生物系(Department of cell science and microbiology, University of Florida)学习。2011年6月应聘南京师范大学“高层次人才”项目,历任副教授和教授。目前主要以人类致病真菌烟曲霉为材料,利用遗传学和分子生物学技术手段,研究真菌致病因子形成相关的调控机制为抗真菌药物的开发提供靶标。以第一或通讯作者在Molecular Microbiology、Cellular Microbiology、Virulence、Applied Environmental Microbiology等国际权威杂志发表论文10余篇。

研究领域

人类病原真菌致病机制和抗真菌药物研发

近期论文

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(1)Huang, J., Z. Ma, G. Zhong, D. C. Sheppard, L. Lu and S. Zhang (2019). "The mitochondrial thiamine pyrophosphate transporter TptA promotes adaptation to low iron conditions and virulence in fungal pathogen Aspergillus fumigatus." Virulence10(1): 234-247. (通讯作者) (2)Zhang, S., Y. Chen, Z. Ma, Q. Chen, H. Ostapska, F. N. Gravelat, L. Lu and D. C. Sheppard (2018). "PtaB, a lim-domain binding protein in Aspergillus fumigatus regulates biofilm formation and conidiation through distinct pathways." Cell Microbiol20(1). (3)Zhang, S., H. Zheng, Q. Chen, Y. Chen, S. Wang, L. Lu and S. Zhang (2017). "The Lectin Chaperone Calnexin Is Involved in the Endoplasmic Reticulum Stress Response by Regulating Ca(2+) Homeostasis in Aspergillus nidulans." Appl Environ Microbiol83(15).(通讯作者) (4) Wang, S., X. Liu, H. Qian, S. Zhang and L. Lu (2016). "Calcineurin and Calcium Channel CchA Coordinate the Salt Stress Response by Regulating Cytoplasmic Ca2+ Homeostasis in Aspergillus nidulans." Appl Environ Microbiol82(11): 3420-3430.(共同通讯作者) (5)Zhang, S., H. Zheng, N. Long, N. Carbo, P. Chen, P. S. Aguilar and L. Lu (2014). "FigA, a putative homolog of low-affinity calcium system member Fig1 in Saccharomyces cerevisiae, is involved in growth and asexual and sexual development in Aspergillus nidulans." Eukaryot Cell13(2): 295-303.

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