黄鹰 - 南京师范大学

个人简介

黄鹰, 博士，南京师范大学教授，博士生导师。1965年出生，1986年毕业于华东理工大学生物化学工程系生物化学工程专业，获工程学学士学位。1986年至1992年在中科院上海生物工程实验基地从事基因工程研究。1997年毕业于美国德州大学卫生研究中心圣安东尼奥分校生物化学系生物化学专业，获博士学位。1997年至2006年在美国国立卫生研究院(NIH) 尤尼斯·肯尼迪·史瑞沃国家儿童健康与人类发展研究所（NICHD）工作，历任Visiting fellow与Research fellow。2006年至2014年7月南京师范大学生命科学学院特聘教授，2014年8月至今，南京师范大学生命科学学院教授。先后获得5项国家自然科学基金面上项目。以第一作者与通讯作者发国际高水平SCI论文20多篇

研究领域

裂殖酵母中帕金森相关基因DJ-1功能的研究线粒体RNA合成与蛋白质翻译机制的研究酵母中自噬机制的研究

近期论文

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Zhao, Q., Su, Y., Wang, Z., Chen, C, Wu, T and Huang, Y.* Identification of glutathione (GSH)-independent glyoxalase III from Schizosaccharomyces pombe. BMC Evol. Biol., 14: 86 (2014) Zhang, X., Zhao, Q. and Huang, Y.* Partitioning of the nuclear and mitochondrial tRNA 3′-end processing activities between two different proteins in Schizosaccharomyces pombe. J. Biol. Chem., 288, 27415-27422 (2013) Sun, L., Yang, X., Chen, F., Li, R., Li, X., Liu, Z., Gu, Y., Gong, X., Liu, Z., Wei, H., Huang, Y. and Yuan, S.* Paralogous Ribosomal Proteins L32-1 and L32-2 in Fission Yeast May Function Distinctively in Cellular Proliferation and Quiescence by Changing the Ratio of Rpl32 Paralogs. PLoS ONE 8(4): e60689doi:10.1371/journal.pone.0060689 (2013) Li, R., Li, X., Sun, L., Chen, F., Liu, Z., Gu, Y., Gong, X., Liu, Z., Wei, H., Huang, Y. and Yuan, S.* Reduction of Ribosome Level Triggers Flocculation of Fission Yeast Cells. Eukaryot. Cell, 12, 450-459 (2013) Wang, Z., Zheng, J., Peng, J., Zhang, X., Liu, J. and Huang, Y.* Identification and sequence analysis of metazoan tRNA 3'-end processing enzymes tRNase Zs. PLoS ONE;7(9):e44264. doi: 10.1371/journal.pone.0044264 (2012) Chen, P, Gao, R, Chen, S, Pu, L, Li, P., Huang, Y., and Lu, L.* A Pericentrin-Related Protein Homolog in Aspergillus nidulans plays Important Roles in Nucleus Positioning and Cell Polarity by affecting microtubule organization. Eukaryot. Cell, 11, 1520-1530 (2012) Fan, L., Wang, Z, Liu, J., Guo, W., Yan, J. and Huang, Y.* A survey of green plant tRNA 3'-end processing enzyme tRNase Zs, homologs of the candidate prostate cancer susceptibility protein ELAC2. BMC Evol. Biol., 11: 219 (2011) Gan, X., Yang, J., Li, J., Yu, H., Dai, H. and Huang, Y.* The fission yeast Schizosaccharomyces pombe has two distinct tRNase ZLs encoded by two different genes and differentially targeted to the nucleus and mitochondria. Biochem J. 435, 103-111 (2011) Wu, G., Sun, Y, Qu W, Huang, Y., Lu L, Li, L and Shao, W.* Application of GFAT as a novel selection marker to mediate gene expression. PLoS ONE 6(2): e17082. doi:10.1371/journal.pone.0017082 (2011) Zhao, W., Yu, H., Li, S. and Huang, Y.* Identification and analysis of candidate fungal tRNA 3'-end processing endonucleases tRNase Zs, homologs of the putative prostate cancer susceptibility protein ELAC2. BMC Evol. Biol., 10:272 (2010) Zhao, Z., Su, W., Yuan S. and Huang, Y.* Functional conservation of tRNase ZL among Saccharomyces cerevisiae, Schizosaccharomyces pombe and humans. Biochem. J., 422, 483-492 (2009) Yee, N. S., Gong, W., Huang, Y., Lorent, K., Dolan, A. C., Maraia, R. J. and Pack, M. Mutation of zebrafish rpc2 reveals exquisite dependence on RNA polymerase III for the development of the digestive system. PLoS Biology, 5(11), e312 doi:10.1371/journal.pbio.0050312 (2007) Huang, Y., Bayfield, M., Intine, R. and Maraia, R. J. Separate RNA-binding surfaces on the multifunctional La protein mediate distinguishable activities in tRNA maturation. Nat. Struct. Mol. Biol., 13,611-618 (2006) Huang, Y., Intine, R., Mozlin, A., Hasson, S. and Maraia, R. J. Mutations in the RNA polymerase III subunit Rpc11p that decrease RNA 3' cleavage activity increase 3' oligo-U length and La-dependent tRNA processing in fission yeast. Mol. Cell. Biol., 25, 621-636 (2005) Huang, Y., Hamada, M. and Maraia, R. J. RNA polymerase III from the fission yeast, S. pombe. In S. Adhya and S. Garges, (eds), Methods Enzymol., 370, Academic Press, Inc., San Diego, CA, pp.165-173 (2003) Huang, Y., McGillicuddy, E., Weindel, M. Dong, S and Maraia, R. J. The fission yeast TFIIB-related factor, Brf1, limits RNA polymerase III to a TATA-dependent pathway of TBP recruitment. Nucleic Acids Res., 31, 2108-2116 (2003) Huang, Y.* Transcriptional silencing in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Nucleic Acids Res., 30, 1465-1482 (2002) Hamada, M., Huang, Y., Lowe, T. M. and Maraia, R. J. Widespread use of TATA elements in the core promoters for RNA polymerase III, II and I in fission yeast. Mol. Cell. Biol., 21, 6870-6881 (2001) Huang, Y.*, Hamada, M., Patel, J. and Maraia, R. J. Construction of FLAG and histidine tagging vectors for Schizosaccharomyce pombe. Yeast, 18, 463-468 (2001) Huang, Y. and Maraia, R. J. Comparison of RNA polymerase III transcription machinery in Schizosaccharomyce pombe, Saccharomyces cerevisiae and humans. Nucleic Acids Res., 29, 2675-2690 (2001) Huang, Y., Hamada, M. and Maraia, R. J. Isolation and cloning of four subunits of a fission Yeast TFIIIC Complex that includes an ortholog of the human regulatory protein TFIIIC. J. Biol. Chem., 275, 31480-31487 (2000)