胡志刚 - 南京师范大学

个人简介

2009年毕业于韩国东亚大学自然资源与生命科学学院，获得理学博士学位。 2010年1月至2013年11月，在世界著名学府斯坦福大学医学院从事科研工作

研究领域

脂代谢，胆固醇代谢，类固醇激素分泌及DNA损伤修复等。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1.Hu Z, Shen WJ, et al., Regulation of adrenal and ovarian steroidogenesis by miR-132. Journal of Molecular Endocrinology. 2017. (Revised). 2. He L, Luo L, Zhu H, Yang H, Zhang Y, Wu H, Sun H, Jiang F, Kathera CS, Liu L, Zhuang Z, Chen H, Pan F, Hu Z, Zhang J, Guo Z.. FEN1 promotes tumor progression and confers cisplatin resistance in non‐small cell lung cancer[J]. Molecular Oncology, 2017. 3. Li J, Zhou Q, Ma Z, Wang M, Shen WJ, Azhar S, Guo Z, Hu Z（通讯作者）. Feedback inhibition of CREB signaling by p38 MAPK contributes to the negative regulation of steroidogenesis[J]. Reproductive Biology and Endocrinology, 2017, 15(1): 19. 4. Pan F, Zhao J, Zhou T, Kuang Z, Dai H, Wu H, Sun H, Zhou X, Wu X, Hu Z, He L, Shen B, Guo Z. Mutation of DNA Polymerase β R137Q Results in Retarded Embryo Development Due to Impaired DNA Base Excision Repair in Mice. Sci Rep. 2016, 6:28614. 5. Sun H, He L, Wu H, Pan F, Wu X, Zhao J, Hu Z, Sekhar C, Li H, Zheng L, Chen H, Shen BH, Guo Z. The FEN1 L209P mutation interferes with long-patch base excision repair and induces cellular transformation[J]. Oncogene, 2016. 6. Hu Z（一作并通讯）, Li J, Kuang Z, et al. Cell-Specific Polymorphism and Hormonal Regulation of DNA Methylation in Scavenger Receptor Class B, Type I[J]. DNA and cell biology, 2016, 35(6): 280-289. 7. Zhou X, Zhuang Z, Wang W, He L, Wu H, Cao Y, Pan F, Zhao J, Hu Z, Sekhar C, Guo Z. OGG1 is essential in oxidative stress induced DNA demethylation. Cell Signal. 2016, 28(9):1163-1171. 8. Shen W J, Hu Z, Hu J, et al. Post-transcriptional and Post-translational Regulation of Steroidogenesis[M]//Post-transcriptional Mechanisms in Endocrine Regulation. Springer International Publishing, 2016: 253-275. 9. Zhou T, Pan F, Cao Y, Han Y, Zhao J, Sun H, Zhou X, Wu X, He L, Hu Z, Chen H, Shen B, Guo Z.. R152C DNA Pol β mutation impairs base excision repair and induces cellular transformation. Oncotarget, 2016, 7(6): 6902. 10. Hu Z, Hu J, Shen W J, et al. A Novel Role of Salt-Inducible Kinase 1 (SIK1) in the Post-Translational Regulation of Scavenger Receptor Class B Type 1 Activity. Biochemistry, 2015, 54(46):6917-30. 11. Cao Y, .. Hu Z.., Guo Z. Selection and characterization of human PCSK9 antibody from phage displayed antibody library[J]. Biochemical and biophysical research communications, 2015, 463(4): 712-718. 12. Shen W J, Hu J, Hu Z, et al. Scavenger receptor class B type I (SR-BI): a versatile receptor with multiple functions and actions[J]. Metabolism, 2014, 63(7): 875-886. 13. Hu Z, Shen W J, Cortez Y, et al. Hormonal regulation of microRNA expression in steroid producing cells of the ovary, testis and adrenal gland[J]. PloS one, 2013, 8(10): e78040-e78040. 14. Hu, Z., Hu, J., Zhang, Z., Shen, W. J., Yun, C. C., Berlot, C. H., ... & Azhar, S. (2013). Regulation of Expression and Function of Scavenger Receptor Class B, Type I (SR-BI) by Na+/H+ Exchanger Regulatory Factors (NHERFs). Journal of Biological Chemistry, 288(16), 11416-11435. 15. Hu, Z, et al. MicroRNAs 125a and 455 Repress Lipoprotein-Supported Steroidogenesis by Targeting Scavenger Receptor Class B Type I in Steroidogenic Cells. Molecular and Cellular Biology, 2012, 32(24): 5035-5045. 16. Hu Z., Lee K.S., et al. Molecular characterization of 1-Cys and 2-Cys peroxiredoxins from the bumblebee Bombus ignitus. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2010, 155(3): 272-280 17. Hu Z. et al. Molecular characterization of a phospholipid hydroperoxide glutathione peroxidase from the bumblebee Bombus ignitus. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2010, 155(1): 54-61 18. Xin Y., Choo Y.M., Hu Z., et al. Molecular cloning and characterization of a venom phospholipase A(2) from the bumblebee Bombus ignitus. Comp Biochem Physiol B Biochem Mol Biol. 2009, 154(2): 195-202. 19. Hu Z., & Sohn, H. D. (2009). Molecular Cloning and Characterization of a Lipocalin in the Bumblebee Bombus Ignitus. International Journal of Industrial Entomology, 19(2), 229-235. 20. Hu Z., et al. Molecular Cloning and Characterization of a Muscle-Specific Lipase from the Bumblebee Bombus ignitus.International Journal of Industrial Entomology, 2008, 17(1): 143-151.