龚劲松 - 江南大学

个人简介

2004.09.-2008.06. 中南林业科技大学生命科学学院，工学学士 2008.09.-2013.12. 江南大学生物工程学院，工学博士 2014.01.-2016.08. 江南大学药学院，校聘副教授 2016.09.-至今江南大学药学院，副教授、硕士生导师

研究领域

长期以蛋白质工程、合成生物学、材料化学、微生物制药和发酵工程等技术方法开展医药中间体的生物催化方面的研发工作

近期论文

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Yao Z-Y, Qin J, Gong J-S*, Ye Y-H, Qian J-Y, Li H, Xu Z-H, Shi J-S*. Versatile strategies for bioproduction of hyaluronic acid driven by synthetic biology. Carbohydrate Polymers, 2021, 264: 118015. Su C, Gong J-S*, Qin J, Li H, Li H, Xu Z-H, Shi J-S*. The tale of a versatile enzyme: Molecular insights into keratinase for its industrial dissemination. Biotechnology Advances, 2020, 45:107655. Ye J-P, Gong J-S*, Su C, Liu Y-G, Jiang M, Pan H, Li R-Y, Geng Y, Xu Z-H, Shi J-S*. Fabrication and characterization of high molecular keratin based nanofibrous membranes for wound healing. Colloids and Surfaces B: Biointerfaces, 2020, 194:111158. Su C, Gong J-S*, Ye J-P, He J-M, Li R-Y, Jiang M, Geng Y, Zhang Y, Chen J-H, Xu Z-H, Shi J-S*. Enzymatic Extraction of Bioactive and Self-Assembling Wool Keratin for Biomedical Applications. Macromolecular Bioscience, 2020, 20 (9):2000073.(封面论文) Gong J-S, Ye J-P, Tao L-Y, Su C, Qin J, Zhang Y-Y, Li H, Li H, Xu Z-H, Shi J-S*. Efficient keratinase expression via promoter engineering strategies for degradation of feather wastes. Enzyme and Microbial Technology, 2020, 137:109550. Su C, Gong J-S*, Qin J, He J-M, Zhou Z-C, Jiang M, Xu Z-H, Shi J-S*. Glutathione enables full utilization of wool wastes for keratin production and wastewater decolorization. Journal of Cleaner Production, 2020, 270:122092. Su C, Gong J-S*, Sun Y-X, Qin J, Zhai S, Li H, Li H, Lu Z-M, Xu Z-H, Shi J-S*. Combining Pro-peptide Engineering and Multisite Saturation Mutagenesis To Improve the Catalytic Potential of Keratinase. ACS Synthetic Biology, 2019, 8 (2):425-433. Gong J-S, Zhang Q, Gu B-C, Dong T-T, Li H, Li H, Lu Z-M, Shi J-S*, Xu Z-H*. Efficient biocatalytic synthesis of nicotinic acid by recombinant nitrilase via high density culture. Bioresource Technology, 2018, 260:427-431. Gong J-S, Shi J-S, Lu Z-M, Li H, Zhou Z-M, Xu Z-H*. Nitrile-converting enzymes as a tool to improve biocatalysis in organic synthesis: Recent insights and promises. Critical Reviews in Biotechnology, 2017, 37 (1):69-81. Gong J-S, Dong T-T, Gu B-C, Li H, Dou W-F, Lu Z-M, Zhou Z-M, Shi J-S, Xu Z-H*. Semirational engineering accelerates the laboratory evolution of nitrilase catalytic efficiency for nicotinic acid biosynthesis. ChemCatChem, 2017, 9 (17):3395-3401. Gong J-S, Li H, Lu Z-M, Zhang X-J, Zhang Q, Yu J-H, Zhou Z-M, Shi J-S, Xu Z-H*. Engineering of a fungal nitrilase for improving catalytic activity and reducing by-product formation in the absence of structural information. Catalysis Science & Technology, 2016, 6: 4134-4141.