个人简介
学习经历
2009.12 江南大学发酵工程专业,获工学博士学位。
2000.07 无锡轻工大学生物工程专业,获工学学士学位
工作经历
2018.06-至今 江南大学药学院 研究员
2012.03 -2018.06 上海医药工业研究院 课题组长(PI)
2009.12 -2012.03 上海医药工业研究院 博士后
2002.03-2005.03 烟台麦得津生物工程股份有限公司
2000.07-2002.03 烟台啤酒朝日有限公司
研究领域
主要从事创新药物研发、药物及其中间体的生物合成研究
近期论文
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Liyuan Yang, Jun Lin, Bin Zhou, Yangang Liu, Baoquan Zhu. Activity of compounds from Taxillus sutchuenensis as inhibitors of HCV NS3 serine protease. Nat Prod Res. 2017, 31(4): 487-491.
Xianglei Liu, Jun Lin*, Haifeng Hu, Bin Zhou, Baoquan Zhu. Site-specific integration and constitutive expression of key genes into Escherichia coli chromosome increases shikimic acid yields. Enzyme Microb Technol. 2016, 82:96-104.
Xianglei Liu, Jun Lin*, Haifeng Hu, Bin Zhou, Baoquan Zhu. Enhanced production of shikimic acid using the strategy of multi-gene coexpression in Escherichia coli. Chin J Nat Med, 2016, 14(4):286-293.
Xianglei Liu, Jun Lin, Haifeng Hu, Bin Zhou, Baoquan Zhu. De novo biosynthesis of resveratrol by site-specific integration of heterologous genes in Escherichia coli. FEMS Microbiol Lett. 2016, 363(8):fnw061.
Liyuan Yang, Jun Lin, Bin Zhou, Yangang Liu, Baoquan Zhu. H1-A, a compound isolated from Fusarium oxysporum inhibits hepatitis C virus (HCV) NS3 serine protease. Chin J Nat Med. 2016, 14(4): 299-302.
Xianglei Liu, Jun Lin*, Haifeng Hu, Bin Zhou, Baoquan Zhu. Metabolic engineering of Escherichia coli to enhance shikimic acid production from sorbitol. World J Microb Biot. 2014, 30: 2543-2550.
Yuan Tao, Jun Lin*, YouJia Hu, Bin Zhou, Baoquan Zhu. Development of a quantitative ELISA kit for human secreted CD306/LAIR-2 and its application. Chin J Nat Med. 2014, 12(11): 0847−0852.
Jun Lin, Haifeng Hu, Youjia Hu, Baoquan Zhu. Expression of a truncated H1N1 neuraminidase and high-throughput screening of its inhibitor. Chin J Nat Med. 2011, 9(5): 380-384.
Jun Lin, Xianyan Liao, Guocheng Du, Jian Chen. Use of Escherichia coli add/ade mutant and Saccharomyces cerevisiae WSH2 to construct a highly efficient coupled system for glutathione production. Enzyme Microb Technol. 2010, 46(2):82-86.
Jun Lin, Xianyan Liao, Guocheng Du, Jian Chen. Enhancement of glutathione production in a coupled system of adenosine deaminase-deficient recombinant Escherichia coli and Saccharomyces cerevisiae. Enzyme Microb Technol. 2009, 44(5): 269-273.
Jun Lin, Xianyan Liao, Juan Zhang, Guocheng Du, Jian Chen. Enhancement of glutathione production with a tripeptidase-deficient recombinant Escherichia coli. J Ind Microbiol Biot. 2009, 36:1447-1452.