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个人简介

孙嘉,江南大学食品学院教授、博士生导师,江苏省双创团队领军人才,江苏省双创计划人才。担任Front Immunol (IF: 5.5)杂志副主编、Engineering (IF: 2.7)杂志青年通讯专家。中国研究型医院学会营养医学专委会委员,中国研究型医院学会食物过敏学组委员,江苏省免疫学会青工委常委,江苏省药理学会抗炎免疫专委会委员。 2009-2013年在瑞典卡罗林斯卡医学院生物物理与生物化学系Kemi II课题组(founded by诺贝尔生理或医学奖获得者Bengt Samuelsson教授)从事生物活性物质与炎症、免疫性疾病调控的博士后研究工作,合作导师为Jesper Z Haeggstrӧm和Birgitta Agerberth。期间作为负责人获得瑞典卡罗林斯卡研究基金会(KI fonder)课题及会议资助,瑞典Rolf Luft糖尿病基金会颁发Rolf Luft Fellowship研究奖(当年唯一)、瑞典国家科学基金会(VR)资助CERIC炎症与慢性疾病卓越研究中心项目。 教育背景 博士后,活性物质与免疫调节,瑞典卡罗琳斯卡医学院 博士,免疫药理学,新加坡国立大学 学士,生物医学,新加坡国立大学

研究领域

研究方向为营养免疫学,长期从事营养组分与机体免疫调节及相关重大慢性疾病干预研究,致力于解决膳食营养、肠道菌群及其活性代谢物参与机体免疫、代谢平衡等领域内重要科学问题

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1) Sun J, Laetitia Furio, Ramine Mecheri, Anne M. van der Does, Erik Lundeberg, Loredana Saveanu, Yong Chen, Peter van Endert, Birgitta Agerberth, Julien Diana. Pancreatic β-cells express a host defense peptide regulating autoimmune diabetes under the influence of the gut microbiota. Immunity. 2015; 43: 304-317. (IF: 24.1) 2) Bei Y#, Pan LL#, Zhou Q#, Zhao C, Xie Y, Wu C, Meng X, Gu H, Xu J, Zhou L, Sluijter JPG, Das S, Agerberth B, Sun J*, Xiao J*. Cathelicidin-related antimicrobial peptide protects against myocardial ischemia/reperfusion injury. BMC Med. 2019. DOI: 10.1186/s12916-019-1268-y. (IF: 9.1) 3) Pan X, Fang X, Wang F, Li H, Niu W, Liang W, Wu C, Li J, Tu X, Pan LL, Sun J*. Butyrate ameliorates caerulein-induced acute pancreatitis and associated intestinal injury by tissue specific mechanisms. Br J Pharmacol. 2019 Jul 26. doi: 10.1111/bph.14806. (IF: 6.6) 4) Liu H, Pan LL, Lv S, Yang Q, Zhang H, Chen W, Lv Z, Sun J*. Alterations of Gut Microbiota and Blood Lipidome in Gestational Diabetes Mellitus With Hyperlipidemia. Front Physiol. 2019 Aug 6;10:1015. doi: 10.3389/fphys.2019.01015. 5) Wu C, Pan LL, Luo Y, Niu W, Fang X, Liang W, Li J, Li H, Pan X, Yang G, Chen W, Zhang H, Lakey JRT, Agerberth B, de Vos P, Sun J*. Low Methoxyl Pectin Protects against Autoimmune Diabetes and Associated Caecal Dysfunction. Mol Nutr Food Res. 2019 Aug 18:e1900307. doi: 10.1002/mnfr.201900307. 6) Wu C, Pan LL, Niu W, Fang X, Liang W, Li J, Li H, Pan X, Chen W, Zhang H, Lakey JRT, Agerberth B, de Vos P, Sun J*. Modulation of Gut Microbiota by Low Methoxyl Pectin Attenuates Type 1 Diabetes in Non-obese Diabetic Mice. Front Immunol. 2019 Jul 30;10:1733. doi: 10.3389/fimmu.2019.01733. eCollection 2019. 7) Pan LL, Niu W, Fang X, Liang W, Li H, Chen W, Zhang H, Bhatia M, Sun J*. Clostridium butyricum Strains Suppress Experimental Acute Pancreatitis by Maintaining Intestinal Homeostasis. Mol Nutr Food Res. 2019 Apr 29:e1801419. doi: 10.1002/mnfr.201801419. [Epub ahead of print] 8) Sun J*, de Vos P. Editorial: Immunomodulatory Functions of Nutritional Ingredients in Health and Disease. Front Immunol. 2019 Jan 24;10:50. doi: 10.3389/fimmu.2019.00050. eCollection 2019. 9) Ren Z, Li H, Zhang M, Zhao Y, Fang X, Li X, Chen W, Zhang H, Wang Y, Pan LL, Sun J*. A Novel Derivative of the Natural Product Danshensu Suppresses Inflammatory Responses to Alleviate Caerulein-Induced Acute Pancreatitis. Front Immunol. 2018; 9:2513. (IF: 5.5) 10) Pan LL, Deng Y-Y, Wang R, Wu C, Li J, Niu W, Yang Q, Madhav B, Gudmundsson HG, Agerberth B, Diana J and Sun J*. Lactose Induces Phenotypic and Functional Changes of Neutrophils and Macrophages to Alleviate Acute Pancreatitis in Mice. Front Immunol. 2018; 9:751. (IF: 5.5) 11) He Y, Wu C, Li J, Li H, Sun Z, Zhang H, de Vos P, Pan LL*, Sun J*. Inulin-Type Fructans Modulates Pancreatic-Gut Innate Immune Responses and Gut Barrier Integrity during Experimental Acute Pancreatitis in a Chain Length-Dependent Manner. Front Immunol. 2017; 8:1209. (IF: 5.5) 12) Jia L, Shan K, Pan LL, Feng N, Lv Z, Sun Y, Li J, Wu C, Zhang H, Chen W, Diana J, Sun J*, Chen YQ*. Clostridium butyricum CGMCC0313.1 Protects against Autoimmune Diabetes by Modulating Intestinal Immune Homeostasis and Inducing Pancreatic Regulatory T Cells. Front Immunol. 2017; 8:1345. (IF: 5.5) 13) Pan LL, Li J, Shamoon M, Bhatia M, Sun J*. Recent Advances on Nutrition in Treatment of Acute Pancreatitis. Front Immunol. 2017; 8:762. (IF: 5.5) 14) Sun J*, Xu M, Diana J, Ortsäter H, ‎Flodström-Tullberg M, Haeggström Z. J, Agerberth B. The antimicrobial peptide cathelicidin is a positive regulator of pancreatic β-cell function. FASEB J. 2016; 30: 884-894. (IF: 5.6) 15) Muhammad Shamoon, Yongquan Chen, Madhav Bhatia*, Sun J*. Therapeutic implications of innate immune system in acute pancreatitis. Expert Opin Ther Targets. 2016; 20: 73-87. (IF: 4.9) 16) Chen K, Chen H, M Faas M, J de haan B, Li J, Xiao P, Zhang H, Diana J, de Vos P, Sun J*. Specific inulin-type fructan fibers protect against autoimmune diabetes by modulating gut immunity, barrier function and microbiota homeostasis. Mol Nutr Food Res 2017; 61(8) (IF: 5.2) 17) Sun Y, He Y, Wang F, Zhang H, de Vos P, Sun J*. Low-methoxyl lemon pectin attenuates inflammatory responses and improves intestinal barrier integrity in caerulein-induced experimental acute pancreatitis. Mol Nutr Food Res 2017; 61(4) (IF: 5.2) 18) Dong Z, Shang H, Chen YQ, Pan LL, Bhatia M, Sun J*. Sulforaphane protects pancreatic acinar cell injury by modulating Nrf2-mediated oxidative stress and NLRP3 inflammatory pathway. Oxid Med Cell Longev 2016; 2016:7864150. (IF: 4.9) 19) Sun J, Dahlén B, Agerberth B, Haeggström ZJ. The host defense peptide LL-37 induces release of eicosanoids and eosinophil cationic protein from human eosinophils – implications for asthma. Allergy. 2013;68:304-311. (IF: 6.0) 20) Sun J, Ramnath RD, Tamizhselvi R, Bhatia M. PKC and PI3K-Akt Pathways are Involved in Substance P-Induced ERK1/2-NF-κB Activation and Chemokine Expression in Mouse Macrophages. FASEB J. 2009;23:997-1010. (IF: 6.401) 21) Sun J, Ramnath RD, Zhi L, Tamizhselvi R, Bhatia M. Substance P Enhances NF-κB Transactivation and Chemokine Response in Murine Macrophages via ERK1/2 and p38 MAPK Signaling Pathways. Am J Physiol Cell Physiol. 2008; 294:C1586-1596. (IF: 4.230)

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