个人简介
工作经历
2017.06-至今江南大学生物工程学院副教授
2015.01-2017.06江南大学生物工程学院讲师
学习经历
2011.09-2015.01江南大学生物工程学院博士
2008.09-2011.07福建农林大学生命科学学院硕士
2004.09-2008.07江西理工大学材料与化学工程学院学士
其中
2016.02-至今寿光巨能玉米开发有限公司博士后
研究领域
长期从事应用微生物代谢工程及合成生物学技术构建高效微生物细胞工厂生产精细化工品的研究
近期论文
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[1]JianZ.Xu(*),HanK.Yang,andWeiG.Zhang,NADPHmetabolism:asurveyofitstheoreticalcharacteristicsandmanipulationstrategiesinaminoacidbiosynthesis,CriticalReviewsinBiotechnology,2018,38(7):1061-1076.
[2]JianZ.Xu(*),HanK.Yang,LiM.Liu,YingY.Wang,andWeiG.Zhang,RationalmodificationofCorynebacteriumglutamicumdihydrodipicolinatereductasetoswitchthenucleotide-cofactorspecificityforincreasingL-lysineproduction,BiotechnologyandBioengineering.2018,115:1764-1777.
[3]JianZ.Xu(*),ZeH.Wu,ShiJ.Gao(*),andWeiG.Zhang,RationalmodifcationoftricarboxylicacidcycleforimprovingL-lysineproductioninCorynebacteriumglutamicum,MicrobialCellFactories,2018,17:105-118.
[4]LiY.Feng,JianZ.Xu(*),andWeiG.Zhang(*),ImprovedL-leucineproductioninCorynebacteriumglutamicumbyoptimizingtheaminotransferases,Molecules2018,23:2102-2115.
[5]MeiHan,JianZ.Xu(*),ZhenM.Liu,HeQian,andWeiG.Zhang,Co-productionofmicrobialoilandexopolysaccharidebytheoleaginousyeastSporidioboluspararoseusgrowninfed-batchculture,RSCAdvance,2018,8:3348-3356.
[6]JianZ.Xu(*),WeiL.Yan,andWeiG.Zhang,Enhancingmenaquinone-7productioninrecombinantBacillusamyloliquefaciensbymetabolicpathwayengineering,RSCAdvances,2017,7:28527–28534.
[7]JianZ.Xu(*),JunL.Zhang,MeiHan,andWeiG.Zhang,AmethodforsimultaneousgeneoverexpressionandinactivationintheCorynebacteriumglutamicumgenome,JournalofIndustrialMicrobiology&Biotechnology,2016,43(10):1417-1427.
[8]JianZ.Xu,MeiHan,XiD.Ren(*),andWeiG.Zhang(*),ModificationofaspartokinaseIIIanddihydrodipicolinatesynthetaseincreasestheproductionofL-lysineinEscherichiacoli,BiochemicalEngineeringJournal,2016,114:82-89.
[9]JianZ.Xu,JunL.Zhang,YanF.Guo,andWeiG.Zhang(*),Geneticallymodifyingaspartateaminotransferaseandaspartateammonia-lyaseaffectsmetaboliteaccumulationinL-lysineproducingstrainderivedfromCorynebacteriumglutamicumATCC13032,JournalofMolecularCatalysisB:Enzymatic,2015,113:82-89.
[10]JianZ.Xu,MeiHan,JunL.Zhang,YanF.Guo,andWeiG.Zhang(*),MetabolicengineeringCorynebacteriumglutamicumfortheL-lysineproductionbyincreasingthefluxintoL-lysinebiosyntheticpathway,AminoAcids,2014,46(9):2165-2175.
[11]JianZ.Xu,MeiHan,JunL.Zhang,YanF.Guo,HeQian,andWeiG.Zhang(*),ImprovementofL-lysineproductioncombineswithminimizationofby-productssynthesisinCorynebacteriumglutamicum,JournalofChemicalTechnology&Biotechnology,2014,89(12):1924-1933.
[12]JianZ.Xu(*),JunL.Zhang,YanF.Guo,YuiG.Zai,andWeiG.Zhang,ImprovementofcellgrowthandL-lysineproductionbygeneticallymodifiedCorynebacteriumglutamicumduringgrowthonmolasses,JournalofIndustrialMicrobiology&Biotechnology,2013,40(12):1423-1432.
[13]JianZ.Xu,JunL.Zhang,KaiH.Hu(*),andWeiG.Zhang(*),Therelationshipbetweenligninperoxidaseandmanganeseperoxidaseproductioncapacitiesandcultivationperiodsofmushrooms,MicrobialBiotechnology,2013,6(3):241-247.