张显 - 江南大学 - 生物工程学院

个人简介

2017.06~至今江南大学，生物工程学院，硕士生导师 2016.09~至今江南大学，生物工程学院，副教授 2014.03~2016.08江南大学，生物工程学院，讲师 2007.09~2014.01江南大学，发酵工程专业，工学博士 2003.09~2007.06江南大学，生物科学专业，理学学士 2018.10~2019.10美国俄亥俄州立大学，化学与生化分子工程系，访问学者

研究领域

主要从事发酵微生物选育、工业微生物代谢工程育种、工业/食品用酶开发等研究，近年来在微生物发酵法生产四碳基平台化合物、生物催化法生产高值氨基酸、工业/食品用酶改良等方面开展多项工作

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1.ZhangXianΔ,ZhangRongzhenΔ,BaoTeng,RaoZhiming,YangTaowei,XuMeijuan,XuZhenghong,LiHuazhong,YangShangtian.Therebalancedpathwaysignificantlyenhancesacetoinproductionbydisruptionofacetoinreductasegeneandmoderate-expressionofanewwater-formingNADHoxidaseinBacillussubtilis[J].MetabolicEngineering,23:34-41,2014. 2.ZhangXian,RaoZhiming*,LiJingjing,ZhouJunping,YangTaowei,XuMeijuan,BaoTeng,ZhaoXiaojing.ImprovingtheacidicstabilityofStaphylococcusaureusαacetolactatedecarboxylaseinBacillussubtilisbychangingbasicresiduestoacidicresidues[J].AminoAcids,47(4):707–717,2015. 3.ZhangXianΔ,BaoTengΔ,RaoZhiming,YangTaowei,XuZhenghong,YangShangtian,LiHuazhong.Two-stagepHControlStrategyBasedonThepHPreferenceofAcetoinReductaseRegulatesAcetoinand2,3-butanediolDistributioninBacillussubtilis[J].PLoSOne,9(3):e91187,2014. 4.ZhangXian,ZhangRongzhen*,BaoTeng,YangTaowei,XuMeijuan,LiHuazhong,XuZhenghong,RaoZhiming*.ModerateexpressionofthetranscriptionalregulatorALsRenhancesacetoinproductionbyBacillussubtilis[J].JIndMicrobiolBiotechnol,40(9):1067-1076,2013. 5.ZhangXian,YangTaowei,LinQing,XuMeijuan,XiaHaifeng,XuZhenghong,LiHuazhong,RaoZhiming*.Isolationandidentificationofanacetoinhighproductionbacteriumthatcanreversetransform2,3-butanedioltoacetoinatthedeclinephaseoffermentation[J].WorldJMicrobiolBiotechnol,27(12):2785-2790,2011. 6.ZhangXian,ZhangRongzhen*,YangTaowei,ZhangJing,XuMeijuan,LiHuazhong,XuZhenghong,RaoZhiming*.MutationbreedingofacetoinhighproducingBacillussubtilisblockedin2,3-butanedioldehydrogenase[J].WorldJMicrobiolBiotechnol,29:1783-1789,2013. 7.XianZhang,Zhiming*R,ZhangL,MeijuanX,TaoweiY.Efficient9α-hydroxy-4-androstene-3,17-dioneproductionbyengineeredBacillussubtilisco-expressingMycobacteriumneoaurum3-ketosteroid9α-hydroxylaseandB.subtilisglucose1-dehydrogenasewithNADHregeneration.SpringerPlus5:1207,2016.