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个人简介

学习经历 2009.08-2014.12,美国韦恩州立大学,化学系,化学博士,导师:郭忠武 2005.08-2009.07,中国科学技术大学,化学系,化学学士,管理学士(双学位) 工作经历 2016.04-至今,江南大学,生物工程学院,副研究员,硕导(2017年起) 2015.01-2016.04,美国韦恩州立大学,化学系,博士后

研究领域

长期从事基于糖抗原的抗肿瘤、细菌等疫苗的合成及生物学研究,代谢糖工程、生物大分子标记等的化学生物学研究,肿瘤免疫治疗、糖尿病相关药物开发等研究。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

(16)XiaozhongCheng,HaofeiHong,ZhifangZhou,andZhimengWu*,EnzymaticOn-ResinPeptideCleavageandinSituCyclizationOne-PotStrategyfortheSynthesisofCyclopeptideandCyclotide,J.Org.Chem.2018,Oct2,DOI:10.1021/acs.joc.8b02032,IF=4.805 (15)ZhifangZhou,HanLin,ChenLi,ZhimengWu*,Recentprogressoffullysyntheticcarbohydrate-basedvaccineusingTLRagonistasbuild-inadjuvant,ChineseChemicalLetters,2018,29,19-26.IF=2.631 (14)ZhifangZhou,WenzhangDing,ChenLi,ZhimengWu*,Synthesisandimmunologicalstudyofawallteichoicacid-basedvaccineagainstE.faeciumU0317,JournalofCarbohydrateChemistry,2017,36:4-6,205-219 (13)ZhifangZhou#(contributedequally),SatadruS.Mandal#,GuochaoLiao#,JiatongGuo,ZhongwuGuo*,SynthesisandEvaluationofGM2-MonophosphorylLipidAConjugateasaFullySyntheticSelf-AdjuvantCancerVaccine,ScientificReports,2017,7:11403,IF=4.122 (12)XiaozhongCheng,TaoZhu,HaofeiHong,ZhifangZhou,ZhimengWu*,SortaseA-mediatedon-resinpeptidecleavageandinsituligation:anefficientone-potstrategyforthesynthesisoffunctionalpeptidesandproteins,Org.Chem.Front.,2017,4,2058-2062.IF=5.455 (11)JianGao,ZhifangZhou,JiatongGuo,ZhongwuGuo*,Synthesisofbiotin-labelledcoreglycansofGPIanchorsandtheirapplicationinthestudyofGPIinteractionwithpore-formingbacterialtoxins,Chem.Commun.,2017,53,6227-6230.IF=6.290 (10)ZhimengWu*,XiaozhongCheng,HaofeiHong,XinruiZhao,ZhifangZhou,Newpotentandselectiveavb3integrinligands:MacrocyclicpeptidescontainingRGDmotifsynthesizedbysortaseA-mediatedligation,Bioorganic&MedicinalChemistryLetters,2017,27,1911-1913IF=2.422 (9)GuochaoLiao#,ZhifangZhou#(contributedequally),SharadSuryawanshi,MohabulA.Mondal,ZhongwuGuo*,FullySyntheticSelf-Adjuvantingα-2,9-OligosialicAcidBasedConjugateVaccinesagainstGroupCMeningitis,ACSCent.Sci.,2016,2,210-218.IF=11.228 (8)GuochaoLiao#,ZhifangZhou#(contributedequally),JunLiao,LuningZu,QiuyeWu,ZhongwuGuo*,6-O-BranchedOligo-β-glucan-BasedAntifungalGlycoconjugateVaccines,ACSInfect.Dis.,2016,2,123-131IF=4.325 (7)ZhifangZhou#(contributedequally),GuochaoLiao#,SatadruS.Mandal,SharadSuryawanshi,ZhongwuGuo*,Afullysyntheticself-adjuvantinggloboH-BasedvaccineelicitedstrongTcell-mediatedantitumorimmunity,Chem.Sci.,2015,6(12):7112-7121IF=9.063 (6)GuochaoLiao#,ZhifangZhou#(contributedequally),ZhongwuGuo*,SynthesisandImmunologicalStudyofα-2,9-OligosialicAcidConjugatesasAnti-groupCMeningitisVaccines,Chem.Comm.,2015,51:9647-9650IF=6.290 (5)Guochao,Liao,SrinivasBurgula,ZhifangZhou,ZhongwuGuo*,AConvergentSynthesisof6-O-Branchedβ-GlucanOligosaccharides,Eur.J.Org.Chem.,2015,(13):2942-2951,IF=2.882 (4)GuochaoLiao#,ZhifangZhou#(contributedequally),SrinivasBurgula,JunLiao,ChengYuan,QiuyeWu,ZhongwuGuo*,SynthesisandImmunologicalStudiesofLinearOligosaccharidesofβ-GlucanAsAntigensforAntifungalVaccineDevelopment,BioconjugateChem.,2015,26(3):466-476IF=4.485 (3)ZhifangZhou,GuochaoLiao,SergejsStepanovs,ZhongwuGuo*,QuantifyingtheEfficiencyofN-Phenyl-D-mannosaminetoMetabolicallyEngineerSialicAcidonCancerCellSurface,JournalofCarohydrateChemistry,2014,33(7-8):395-407 (2)ZhifangZhou#(contributedequally),MohabulMondal#,GuochaoLiao#,ZhongwuGuo*,SynthesisandevaluationofmonophosphoryllipidAderivativesasfullysyntheticself-adjuvantingglycoconjugatecancervaccinecarriers,Org.Biomol.Chem.,2014,12(20):3238-3245,IF=3.423 (1)QianliWang,ZhifangZhou,ShouchuTang,ZhongwuGuo*,Carbohydrate-MonophosphorylLipidAConjugatesAreFullySyntheticSelf-AdjuvantingCancerVaccinesElicitingRobustImmuneResponsesintheMouse,ACSChem.Bio.,2012,7(1):235-240,IF=4.592

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