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个人简介

2003-2007合肥工业大学,生物工程专业,工科学士; 2007-2010四川大学,发酵工程专业,工科硕士; 2010-2014江南大学,发酵工程专业,工科博士。

研究领域

长期从事蛋白质工程和酶工程的研究

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1.Rui-ZhiHan,Guo-ChaoXu,Jin-JunDong,YeNi*.Argininedeiminase:recentadvancesindiscovery,crystalstructureandproteinengineeringforimprovedpropertiesasananti-tumordrug.AppliedMicrobiology&Biotechnology(2016)100:4747-4760 2.Han,R.Z.,Li,J.H.,Shin,H.D.etal.(2014)Recentadvancesindiscovery,heterologousexpression,andmolecularengineeringofcyclodextringlycosyltransferaseforversatileapplications.BiotechnologyAdvances,32,415-428. 3.Han,R.Z.,Li,J.H.,Shin,H.D.etal.(2014)Fusionofself-assemblingamphipathicoligopeptideswithcyclodextringlycosyltransferaseimproves2-O-D-glucopyranosyl-l-ascorbicacidsynthesiswithsolublestarchastheglycosyldonor.AppliedandEnvironmentalMicrobiology,80,4717-4724. 4.Han,R.Z.,Liu,L.,Shin,H.D.etal.(2013)Iterativesaturationmutagenesisof-6subsiteresiduesincyclodextringlycosyltransferasefromPaenibacillusmaceranstoimprovemaltodextrinspecificityfor2-O-d-glucopyranosyl-l-ascorbicacidsynthesis.AppliedandEnvironmentalMicrobiology,79,7562-7568. 5.Han,R.Z.,Li,J.H.,Shin,H.D.etal.(2013)Carbohydrate-bindingmodule-cyclodextringlycosyltransferasefusionenablesefficientsynthesisof2-O-d-glucopyranosyl-l-ascorbicacidwithsolublestarchastheglycosyldonor.AppliedandEnvironmentalMicrobiology,79,3234-3240. 6.Han,R.Z.,Liu,L.,Shin,H.D.etal.(2013)Systemsengineeringoftyrosine195,tyrosine260,andglutamine265incyclodextringlycosyltransferasefromPaenibacillusmaceranstoenhancemaltodextrinspecificityfor2-O-(D)-glucopyranosyl-(L)-ascorbicacidsynthesis.AppliedandEnvironmentalMicrobiology,79,672-677. 7.Han,R.Z.,Liu,L.,Shin,H.D.etal.(2013)Site-saturationengineeringoflysine47incyclodextringlycosyltransferasefromPaenibacillusmaceranstoenhancesubstratespecificitytowardsmaltodextrinforenzymaticsynthesisof2-O-D-glucopyranosyl-L-ascorbicacid(AA-2G).AppliedMicrobiologyandBiotechnology,97,5851-5860. 8.Han,R.Z.,Liu,L.,Li,J.H.etal.(2012)Functions,applicationsandproductionof2-O-D-glucopyranosyl-L-ascorbicacid.AppliedMicrobiologyandBiotechnology,95,313-320

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