个人简介
2003-2007合肥工业大学,生物工程专业,工科学士;
2007-2010四川大学,发酵工程专业,工科硕士;
2010-2014江南大学,发酵工程专业,工科博士。
近期论文
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1.Rui-ZhiHan,Guo-ChaoXu,Jin-JunDong,YeNi*.Argininedeiminase:recentadvancesindiscovery,crystalstructureandproteinengineeringforimprovedpropertiesasananti-tumordrug.AppliedMicrobiology&Biotechnology(2016)100:4747-4760
2.Han,R.Z.,Li,J.H.,Shin,H.D.etal.(2014)Recentadvancesindiscovery,heterologousexpression,andmolecularengineeringofcyclodextringlycosyltransferaseforversatileapplications.BiotechnologyAdvances,32,415-428.
3.Han,R.Z.,Li,J.H.,Shin,H.D.etal.(2014)Fusionofself-assemblingamphipathicoligopeptideswithcyclodextringlycosyltransferaseimproves2-O-D-glucopyranosyl-l-ascorbicacidsynthesiswithsolublestarchastheglycosyldonor.AppliedandEnvironmentalMicrobiology,80,4717-4724.
4.Han,R.Z.,Liu,L.,Shin,H.D.etal.(2013)Iterativesaturationmutagenesisof-6subsiteresiduesincyclodextringlycosyltransferasefromPaenibacillusmaceranstoimprovemaltodextrinspecificityfor2-O-d-glucopyranosyl-l-ascorbicacidsynthesis.AppliedandEnvironmentalMicrobiology,79,7562-7568.
5.Han,R.Z.,Li,J.H.,Shin,H.D.etal.(2013)Carbohydrate-bindingmodule-cyclodextringlycosyltransferasefusionenablesefficientsynthesisof2-O-d-glucopyranosyl-l-ascorbicacidwithsolublestarchastheglycosyldonor.AppliedandEnvironmentalMicrobiology,79,3234-3240.
6.Han,R.Z.,Liu,L.,Shin,H.D.etal.(2013)Systemsengineeringoftyrosine195,tyrosine260,andglutamine265incyclodextringlycosyltransferasefromPaenibacillusmaceranstoenhancemaltodextrinspecificityfor2-O-(D)-glucopyranosyl-(L)-ascorbicacidsynthesis.AppliedandEnvironmentalMicrobiology,79,672-677.
7.Han,R.Z.,Liu,L.,Shin,H.D.etal.(2013)Site-saturationengineeringoflysine47incyclodextringlycosyltransferasefromPaenibacillusmaceranstoenhancesubstratespecificitytowardsmaltodextrinforenzymaticsynthesisof2-O-D-glucopyranosyl-L-ascorbicacid(AA-2G).AppliedMicrobiologyandBiotechnology,97,5851-5860.
8.Han,R.Z.,Liu,L.,Li,J.H.etal.(2012)Functions,applicationsandproductionof2-O-D-glucopyranosyl-L-ascorbicacid.AppliedMicrobiologyandBiotechnology,95,313-320