个人简介
198108-198506 山东大学,微生物学专业,理学学士
198507-198707 山东大学微生物学系,助教
198708-199006 山东大学,微生物学专业,理学硕士
199007-199405 江苏省原子医学研究所,助理研究员
199406-199704 江阴星达生物工程有限公司,总工程师
199705-200509 无锡轻工大学生物工程学院,助理研究员
200510- 江南大学生物工程学院,副研究员
其中
200812 获江南大学发酵工学博士学位
研究领域
长期从事工业微生物学和生物制药方向的研究,主要承担微生物学、微生物遗传育种课程的讲授工作
近期论文
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Effects of co-overexpression of secretion helper factors on the secretion of a HSA fusion protein (IL2-HSA) in Pichia pastoris. Yeast.2016, 33:587-600
Efficient expression of glucagon-like peptide-1 analogue with human serum albumin fusion protein in Pichia pastoris using theglyceraldehyde-3-phosphate dehydrogenase promoter. Biotechnology and Bioprocess Engineering, 2015, 20(4):694-700
Effect of biotin on transcription levels of key enzymes and glutamate efflux in glutamate fermentation by Corynebacteriumglutamicum.World J Microbiol.Biotechnol. 2014 , 30 (2) :461-468
Constitutive Expression of a rhIL-2-HSA Fusion Protein in Pichia pastoris Using Glucose as Carbon Source. Appl BiochemBiotechnol. 2013, 171:1792-1804
Expression, purification and characterization of recombinant human interleukin-2-serum albumin (rhIL-2-HSA) fusion protein in Pichiapastoris. Protein Expression and Purification. 2012, 84(1): 154-1601.
Absence of Yps7p, a putative glycosyl- phosphatidylinositol-linked aspartyl protease in Pichia pastoris, results in aberrant cell wallcomposition and increased osmotic stress resistance. FEMS Yeast Research. 2012, 12:969-979
Properties of an NAD-dependent DNA ligase from the hyperthermophile Thermotoga maritima and its application in PCR amplificationof long DNA fragments. Enzyme and Microbial Technology. 2010, 46(2): 113-117
Enhanced porcine interferon-α production by recombinant Pichia pastoris with a combinational control strategy of low inductiontemperature and high dissolved oxygen concentration. Biochemical Engineering Journal. 2010, 52(1):91-98
Effective and stable porcine interferon-α production by Pichia pastoris fed-batch cultivation with multi-variables clustering andanalysis. Bioprocess and Biosystems Engineering. 2010, 33(4):473-483