个人简介
1999.9-2003.6 江南大学,生物工程专业,工学学士
2003.9-2008.9 江南大学,发酵工程专业,博士学位(硕博连读)
2008.11-2013.3 江南大学生物工程学院,讲师
2013.4-2019.4 江南大学生物工程学院,副教授
2019.5-至今江南大学生物工程学院,教授
其中
2013.12-2014.12 美国系统生物学研究所,Price Lab,博士后
研究领域
长期从事基于系统生物学的微生物群落分析与代谢工程改造及新型食品酶制剂的开发
近期论文
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1. Zheng Peng, Juan Zhang*, Guocheng Du, Jian Chen. Keratin Waste Recycling Based on MicrobialDegradation: Mechanisms and Prospects. ACS Sustainable Chemistry & Engineering, 2019, DOI:10.1021/acssuschemeng.9b01527. (IF=6.140)
2. Zheng Peng, Xinzhe Mao, Juan Zhang*, Guocheng Du, Jian Chen. Effective biodegradation of chickenfeather waste by co‑cultivation of keratinase producing strains. Microbial Cell Factories, 2019, 18:84.(IF=3.831)
3. Zhengming Zhu, Xiaomei Ji, Zhimeng Wu, Juan Zhang*, Guocheng Du. Improved acid‑stresstolerance of Lactococcus lactis NZ9000 and Escherichia coli BL21 by overexpression of the anti‑acidcomponent recT. Journal of Industrial Microbiology and Biotechnology, 2018, 45(12):1091-1101.(IF=3.103)
4. Zhengming Zhu, Juan Zhang*, Xiaomei Ji, Zhen Fang, Zhimeng Wu, Jian Chen, Guocheng Du.Evolutionary engineering of industrial microorganisms-strategies and applications. Applied Microbiologyand Biotechnology, 2018, 102(11):4615–4627. (IF=3.340)
5. Zhen Fang, Juan Zhang*, Guocheng Du, Jian Chen. Rational protein engineering approaches to furtherimprove the keratinolytic activity and thermostability of engineered keratinase KerSMD. BiochemicalEngineering Journal, 2017, 127:147-153. (IF=3.226)
6. Juan Zhang, Yanqiu Cai, Guocheng Du, Jian Chen, Miao Wang, Zhen Kang. Evaluation andapplication of constitutive promoters for cutinase production by Saccharomyces cerevisiae. Journal ofMicrobiology, 2017, 55(7): 538–544. (IF=2.319)
7. Zhen Fang, Juan Zhang*, Guocheng Du, Jian Chen. Improved catalytic efficiency, thermophilicity,anti-salt and detergent tolerance of keratinase KerSMD by partially truncation of PPC domain. ScientificReports. 2016, 1-11. (IF=4.122)
8. Zhen Fang, Juan Zhang*, Baihong Liu, Guocheng Du and Jian Chen. Enhancement of the catalyticefficiency and thermostability of Stenotrophomonas sp. Keratinase KerSMD by domain exchange withKerSMF. Microbial Biotechnology, 2016, 9(1):35-46. (IF=3.913)
9. Chongde Wu , Juan Zhang (共同一作), Guocheng Du and Jian Chen. Heterologous expression ofLactobacillus casei RecO improved the multiple-stress tolerance and lactic acid production inLactococcus lactis NZ9000 during salt stress. Bioresource Technology, 2013, 143: 238-241.(IF=5.807)
10. Juan Zhang, Yin Li, Guocheng Du, Jian Chen. Glutathione improves the cold resistance ofLactobacillus sanfranciscensis by physiological regulation. Food Microbiology, 2012, 31: 285-292.