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个人简介

教育经历 2011.2-2012.2美国俄亥俄州立大学访问学者 1999.9-2002.6 中国农业科学院研究生院,遗传学,博士 工作经历 2017.1 -至今江南大学生物工程学院副院长 2014.1 - 2016.12 江南大学食品科学与技术国家重点实验室副主任;江苏省产业技术研究院食品生物技术研究所常务副所长 2008.10 -至今江南大学,生物工程学院,教授,博士生导师 2008.10 - 2013.12江南大学生物工程学院副院长 2002.7-2008.9 江南大学,生物工程学院,讲师、副教授

研究领域

长期从事发酵工程、代谢工程、酶工程和生物化工领域的研究,以重要工业微生物系统改造发酵调控为手段,着力建立和完善工业微生物代谢途径设计的理论与技术体系,借助系统生物学、代谢工程和合成生物学等新技术,理性设计和改造重要微生物菌株,如棒杆菌、芽孢杆菌、分枝杆菌等重要氨基酸、C4平台化合物、甾体化合物等高值化合物的代谢或转化关联途径,研究细胞全局代谢平衡机理,进行细胞整体代谢网络的适配改造,从而获得适合工业化规模生产要求的优良菌株。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1、Rongzhen Zhang*, Jiawei Jiang, Junping Zhou, Yan Xu*, Rong Xiao, Xinhui Xia,Zhiming Rao*. Biofunctionalized "Kiwifruit-Assembly" of Oxidoreductases inMesoporous ZnO/Carbon Nanoparticles for Efficient Asymmetric Catalysis.Advanced Materials. 2018 Mar;30(11). doi: 10.1002/adma.201705443. Epub 2018Jan 23. (SCI, IF2017= 21.950) 2、Jiajia You, Li Sun, Xiaojing Yang, Xuewei Pan, Zhiwei Huang, Xixi Zhang,Mengxin Gong, Zheng Fan, Lingyan Li, Xiaoli Cui, Zhaoyuan Jing, Shouguang Jin,Zhiming Rao*, Weihui Wu*, Hongjiang Yang*. Regulatory protein SrpA controlsphage infection and core cellular processes in Pseudomonas aeruginosa. NatureCommunications. 2018 May 10;9(1):1846. doi: 10.1038/s41467-018-04232-6. (SCI,IF2017= 12.353) 3、Junping Zhou, Rongzhen Zhang*, Taowei Yang, Qiaoli Liu, Junxian Zheng, FangWang, Fei Liu, Meijuan Xu, Xian Zhang, Zhiming Rao*. Relieving AllostericInhibition by Designing Active Inclusion Bodies and Coating of the Inclusion Bodieswith Fe3O4 Nanomaterials for Sustainable 2-Oxobutyric Acid Production. ACSCatalysis. 2018, 8 (9), 8889–8901. (SCI, IF2017= 11.384) 4、Rongzhen Zhang, Taowei Yang, Zhiming Rao*, Hongmei Sun, Meijuan Xu, XianZhang, Zhenghong Xu, Shangtian Yang. Efficient one-step Preparation of γ-Aminobutyric Acid from Glucose without Exogenous Cofactor by the DesignedCorynebacterium glutamicum. Green Chemistry. 2014, 16(9): 4190-4197. (SCI,IF2017=8.586) 5、Man Zaiwei, Rao Zhiming*, Xu Meijuan, Guo Jing, Yang Taowei, Zhang Xian,Xu Zhenghong*. Improvement of the intracellular environment for enhancing L-arginine production of Corynebacterium glutamicum by inactivation of H2O2-formingflavin reductases and optimization of ATP supply. Metabolic Engineering. 2016,38:310-321. (SCI, IF2017=7.674) 6、Shao Minglong, Zhang Xian, Rao Zhiming*, Xu Meijuan, Yang Taowei, Li Hui,Xu Zhenghong, Yang Shangtian. Efficient testosterone production by engineeredPichia pastoris co-expressing human 17β-hydroxysteroid dehydrogenase type 3 andSaccharomyces cerevisiae glucose 6-phosphate dehydrogenase with NADPHregeneration. Green Chemistry. 2016, 18(6):1774-1784. (SCI, IF2017=8.586) 7、Xian Zhang, Rongzhen Zhang, Teng Bao, Zhiming Rao*, Taowei Yang, MeijuanXu, Zhenghong Xu, Huazhong Li*, Shangtian Yang. The rebalanced pathwaysignificantly enhances acetoin production by disruption of acetoin reductase gene andmoderate-expression of a new water-forming NADH oxidase in Bacillus subtilis.Metabolic Engineering. 2014, 23: 34-41. (SCI, IF2017=7.674) 8、Junxian Zheng, Taowei Yang, Junping Zhou, Meijuan Xu, Xian Zhang, ZhimingRao*, Shangtian Yang. Efficient production of D-amino acid oxidase in Escherichiacoli by a trade-off between its expression and biomass using N-terminal modification.Bioresource Technology. 2017, DOI: http://dx.doi.org/10.1016/j.biortech.2017.07.007(SCI, IF2017=5.807) 9、Yang Taowei, Rao Zhiming*, Hu Guiyuan, Zhang Xian, Liu Mei, Dai Yue, XuMeijuan, Xu Zhenghong, Yang Shangtian. Metabolic engineering of Bacillus subtilisfor redistributing the carbon flux to 2,3-butanediol by manipulating NADH levels.Biotechnology for Biofuels. 2015, 8:129. (SCI, IF2017=5.497)

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