个人简介
学习经历
1980.09-1984.07无锡轻工大学发酵工程系本科
1987.09-1989.12无锡轻工大学发酵工程系硕士研究生
1997.09-2001.07无锡轻工大学生物工程学院博士研究生
研究经历
1984.08-1987.08江苏省食品发酵研究所工作
1990.01-2001.07无锡轻工大学中央研究所工作
2002.08-至今江南大学生物工程学院工作
研究领域
长期从事应用微生物代谢工程及合成生物学技术选育和构建氨基酸高产菌
近期论文
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(1)LiY.Feng,JianZ.Xu(*),andWeiG.Zhang(*),ImprovedL-leucineproductioninCorynebacteriumglutamicumbyoptimizingtheaminotransferases,Molecules2018,23:2102-2115.
(2)MeiHan,JianZ.Xu(*),ZhenM.Liu,HeQian,andWeiG.Zhang,Co-productionofmicrobialoilandexopolysaccharidebytheoleaginousyeastSporidioboluspararoseusgrowninfed-batchculture,RSCAdvance,2018,8:3348-3356.
(3)YanF.Guo,JianZ.Xu,MeiHan,WeiG.Zhang(*)GenerationofmutantthreoninedehydrataseanditseffectsonisoleucinesynthesisinCorynebacteriumglutamicum,WorldJournalofMicrobiology&Biotechnology,2015,31(9):1369~1377
(4)YanF.Guo,MeiHan,JianZ.Xu,WeiG.Zhang(*)Analysisofacetohydroxyacidsynthasevariantsfrombranched-chainaminoacids-producingstrainsandtheireffectsonthesynthesisofbranched-chainaminoacidsinCorynebacteriumglutamicum,ProteinExpression&Purification,2015,109(0):106~112
(5)YanF.Guo,MeiHan,WeiL.Yan,JianZ.Xu,WeiG.Zhang(*)Generationofbranched-chainaminoacidsresistantCorynebacteriumglutamicumacetohydroxyacidsynthasebysite-directedmutagenesis,BiotechnologyandBioprocessEngineering,2014,19(3):456~467
(6)XiaoH.Hou,XiangY.Ge,YueZhang,HeQian,WeiG.Zhang(*)L-valineproductionwithminimizationofby-productssynthesisinCorynebacteriumglutamicumandBrevibacteriumflavum,AminoAcids,2012,43(6):2301~2311
(7)XiaoH.Hou,XiangY.Ge,DiWu,HeQian,WeiG.Zhang(*)ImprovementofL-valineproductionathightemperatureinBrevibacteriumflavumbyoverexpressingilvEBNrCgenes,JournalofIndustrialMicrobiology&Biotechnology,2011,39(1):63~72
(8)HuanM.Liu,WeiG.Zhang(*)PreliminarystudyonmetabolicregulationandcontrolofL-valinefermentationinanewlyscreenedL-valineproducingstrain,AfricanJournalofBiotechnology,2010.5.01,9(9):3308~3317
(9)HuanM.Liu,XiangY.Ge,WeiG.Zhang(*)L-valinefermentationbyBrevibacteriumflavumstrainNV246,AsianJournalofChemistry,2011,23(5):2151~2153
(10)HuanM.Liu,XiangY.Ge,WeiG.Zhang(*)StudyonthebreedingofL-valineproducingmutants(prototrophandauxotroph)andcomparisonoftheirproperties,AsianJournalofChemistry,2011,23(10):4483~4485(11)MeiHan,ZhiY.Xu,ChaoDu,HeQian,WeiG.Zhang(*)EffectsofnitrogenonthelipidandcarotenoidaccumulationofoleaginousyeastSporidioboluspararoseus,BioprocessandBiosystemsEngineering,2016,39(9):1425~1433+18:26