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个人简介

2009年9月- 2011年10月:于上海交通大学微生物代谢国家重点实验室从事博士后研究,主要从事高等真菌次级代谢产物的代谢工程研究。 2004年 9月- 2009年9月: 就读于华东理工大学生物反应器工程国家重点实验室,生物化工专业,获得工学博士学位。 2001年9月- 2004年7月: 就读于青岛化工学院化学工程学院,生物化工专业, 获得硕士学位。 1997年9月- 2001年7月: 就读于河南大学生物系,发酵工程专业,获得学士学位。

研究领域

应用微生物,生物技术,生物制药,微生物代谢工程

近期论文

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1. Jun-Wei Xu*, Tong-Hui Yue, Xuya Yu, Peng Zhao, Tao Li and Na Li (2019) Enhanced production of individual ganoderic acids by integrating Vitreoscilla haemoglobin expression and calcium ion induction in liquid static cultures of Ganoderma lingzhi. Microbial Biotechnology, DOI: 10.1111/1751-7951.1338 2. Lu-Xi Jiang, Li-Liang Han, Hui-Ping Wang, Jun-Wei Xu* and Jian-Hui Xiao (2018) Improved production of jiangxienone in submerged fermentation of Cordyceps jiangxiensis under nitrogen deficiency. Bioprocess and Biosystems Engineering, 41: 1417-1423 3. De-Huai Zhang, Lu-Xi Jiang, Na Li, Xuya Yu, Peng Zhao, Tao Li and Jun-Wei Xu* (2017) Overexpression of the squalene epoxidase gene alone and in combination with the 3-hydroxy-3-methylglutaryl coenzyme A gene increases ganoderic acid production in Ganoderma lingzhi. Journal of Agricultural and Food Chemistry, 65: 4683-4690 4. De-Huai Zhang, Na Li, Xuya Yu, Peng Zhao, Tao Li and Jun-Wei Xu* (2017) Overexpression of the homologous lanosterol synthase gene in ganoderic acid biosynthesis in Ganoderma lingzhi. Phytochemistry, 134: 46-53 5. Huan-Jun Li, Yi-Long He, De-Huai Zhang, Tong-Hui Yue, Lu-Xi Jiang, Na Li and Jun-Wei Xu* (2016) Enhancement of ganoderic acid production by constitutively expressing Vitreoscilla hemoglobin gene in Ganoderma lucidum. Journal of Biotechnology, 227: 35-40 6. Huan-Jun Li, De-Huai Zhang, Tong-Hui Yue, Lu-Xi Jiang, Xuya Yu, Peng Zhao, Tao Li and Jun-Wei Xu* (2016) Improved polysaccharide production in a submerged culture of Ganoderma lucidum by the heterologous expression of Vitreoscilla hemoglobin gene. Journal of Biotechnology, 217: 132-137 7. Huan-Jun Li, De-Huai Zhang, Li-Liang Han, Xuya Yu, Peng Zhao, Tao Li, Jian-Jiang Zhong and Jun-Wei Xu* (2016) Further improvement in ganoderic acid production in static liquid culture of Ganoderma lucidum by integrating nitrogen limitation and calcium ion addition. Bioprocess and Biosystems Engineering, 39: 75-80 8. Jun-Wei Xu* and Jian-Jiang Zhong (2015) Genetic engineering of Ganoderma lucidum for the efficient production of ganoderic acids. Bioengineered, 6: 357-360 9. Jun-Wei Xu*, Sen-Lin Ji, Huan-Jun Li, Meng-Fei Ren, Yan-Qing Duan, Li-Zhi Dang and Ming-He Mo (2015) Increased polysaccharide production and biosynthetic gene expressions in a submerged culture of Ganoderma lucidum by the overexpression of the homologous alpha-phosphoglucomutase gene. Bioprocess and Biosystems Engineering, 38: 399-405 10. Sen-Lin Ji, Rui Liu, Meng-Fei Ren, Huan-Jun Li and Jun-Wei Xu* (2015) Enhanced production of polysaccharide through the overexpression of the homologous UDP glucose pyrophosphorylase gene in a submerged culture of Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (higher basidiomycetes). International Journal of Medicinal Mushrooms, 17: 435-442 11. Jiang-Sheng Zhou, Sen-Lin Ji, Meng-Fei Ren, Yi-Long He, Xiao-Ran Jing and Jun-Wei Xu* (2014) Enhanced accumulation of individual ganoderic acids in a submerged culture of Ganoderma lucidum by the overexpression of squalene synthase gene. Biochemical Engineering Journal, 90: 178-183 12. Xuya Yu, Sen-Lin Ji, Yi-Long He, Meng-Fei Ren and Jun-Wei Xu* (2014) Development of an expression plasmid and its use in genetic manipulation of Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (higher basidiomycetes). International Journal of Medicinal Mushrooms, 16: 161-168 13. Yan-Qing Duan, Zhan-Chang Xing and Jun-Wei Xu* (2013) Screening of a high yield polysaccharide strain from ten edible and medicinal fungi and optimization of its culture conditions. Research Journal of Biotechnology, 8:11-15 14. Jun-Wei Xu, Yi-Ning Xu and Jian-Jiang Zhong (2012) Enhancement of ganoderic acid accumulation by overexpression of an N-terminal truncated 3-hydroxy-3-methylglutaryl CoA reductase gene in the basidiomycete Ganoderma lucidum. Applied and Environmental Microbiology, 78: 7968-7976 15. Jun-Wei Xu, Wei Zhao, Yi-Ning Xu and Jian-Jiang Zhong (2012) Isolation and analysis of differentially expressed genes during asexual sporulation in liquid static culture of Ganoderma lucidum by suppression subtractive hybridization. Molecular Biology Reports, 39: 3603-3610 16. Jun-Wei Xu, Wei Zhao and Jian-Jiang Zhong (2011) Isolation and characterization of a novel Ganoderma lucidum gene that differentially expressed between shaking culture and liquid static culture. Genes & Genomics, 33: 645-651 17. Jun-Wei Xu, Wei Zhao and Jian-Jiang Zhong (2010) Biotechnological production and application of ganoderic acids. Applied Microbiology and Biotechnology, 87: 457-466 18. Jun-Wei Xu, Yi-Ning Xu and Jian-Jiang Zhong (2010) Production of individual ganoderic acids and expression of biosynthetic genes in liquid static and shaking cultures of Ganoderma lucidum. Applied Microbiology and Biotechnology, 85: 941-948

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