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1.Chen Y#,*, Yu J#, Niu Y#, Qin D#, Liu H#, Wang J, Li S, Wang J, Luo Y, Liu J, Kang Y, Wei J, Zhi D, Si C, Bai R, Chen X, Wang H, Bao X, Zhang Q, Li F, Geng R, Liang A, Jiang T, Ma Y, Ji W* and Sun YE*. Modeling Rett Syndrome using TALEN-edited MECP2 Mutant Monkeys. Cell. (Under revision) 2.Cui Y#, Chen Y#, Zhou J#, Niu Y#, Cheng Y, Kang Y, Liu Y, Li T, Ai Z, Lu Z, Zhang Y, Dai J, Si C, Yang Z, Chu, Hu Z, Si W, Wang H, Sha J, Guo X*, Huang X* and Ji W*. Generation of a precise Oct4-hrGFP knockin monkey model via CRISPR/Cas9-assisted homologous recombination. Cell. (Under review) 3.Gao F#, Niu Y#, Sun YE#, Lu H#, Chen Y#, Li S#, Kang Y, Luo Y, Si C, Yu J, Li C, Sun N, Si W, Wang H, Ji W*, Tan T*. De novo DNA methylation during monkey pre-implantation embryogenesis. Cell Res. 2017 Feb 24. doi: 10.1038/cr.2017.25. 4.Chen Y, Niu Y*, Ji W*. Genome editing in non-human primates: approach to generating human diseases models. J Intern Med. 2016 Sep;280(3):246-51. 5.Zhu X, Li B, Ai Z, Xiang Z, Zhang K, Qiu X, Chen Y, Li Y, Rizak JD, Niu Y, Hu X, Sun YE, Ji W, Li T. A Robust Single Primate Neuroepithelial Cell Clonal Expansion System for Neural Tube Development and Disease Studies. Stem Cell Reports. 2016 Feb 9;6(2):228-42. 6.Kang Y#, Zheng B#, Shen B#, Chen Y#, Wang L, Wang J, Niu Y, Cui Y, Zhou J, Wang H, Guo X, Hu B, Zhou Q, Sha J*, Ji W*, Huang X*. CRISPR/Cas9-mediated Dax1 knockout in the monkey recapitulates human AHC-HH. Hum Mol Genet. 2015 Dec 20;24(25):7255-64. 7.Chen Y#, Niu Y#, Li Y#, Ai Z, Kang Y, Shi H, Xiang Z, Yang Z, Tan T, Si W, Li W, Xia X, Zhou Q*, Ji W*, Li T*. Generation of Cynomolgus Monkey Chimeric Fetuses using Embryonic Stem Cells. Cell Stem Cell. 2015 Jul 2;17(1):116-24. 8.Chen Y#, Zheng Y#, Kang Y#, Yang W#, Niu Y, Guo X, Tu Z, Si C, Wang H, Xing R, Pu X, Yang SH, Li S, Ji W*, Li XJ*. Functional disruption of the dystrophin gene in Rhesus Monkey Using CRISPR/Cas9. Hum Mol Genet. 2015; 24(13):3764-3774. 9.Chen Y#, Cui Y#, Shen B#, Niu Y#, Zhao X, Wang L, Wang J, Li W, Zhou Q, Ji W*, Sha J*, Huang X*. Germline acquisition of Cas9/RNA-mediated gene modifications in monkeys. Cell Res. 2015 Feb;25(2):262-5. 10.Niu Y#, Guo X#, Chen Y#, Wang CE, Gao J, Yang W, Kang Y, Si W, Wang H, Yang SH, Li S, Ji W*, Li XJ*. Early Parkinson's disease symptoms in α-synuclein transgenic monkeys. Hum Mol Genet. 2015 Apr 15;24(8):2308-17. 11.Liu H#, Chen Y#, Niu Y#, Zhang K#, Kang Y, Ge W, Liu X, Zhao E, Wang C, Lin S, Jing B, Si C, Lin Q, Chen X, Lin H, Pu X, Wang Y, Qin B, Wang F, Wang H, Si W, Zhou J, Tan T, Li T, Ji S, Xue Z, Luo Y, Cheng L, Zhou Q, Li S*, Sun YE*, Ji W*. TALEN-mediated gene mutagenesis in rhesus and cynomolgus monkeys. Cell Stem Cell. 2014 Mar 6; 14(3):323-8. 12.Niu Y#, Shen B#, Cui Y#, Chen Y#, Wang J, Wang L, Kang Y, Zhao X, Si W, Li W, Xiang AP, Zhou J, Guo X, Bi Y, Si C, Hu B, Dong G, Wang H, Zhou Z, Li T, Tan T, Pu X, Wang F, Ji S, Zhou Q, Huang X*, Ji W*, Sha J*. Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos. Cell. 2014 Feb 13; 156(4):836-43. 13.Liu H#, Zhao B#, Chen Y#, You D, Liu R, Rong M, Ji W*, Zheng P, Lai R*. Multiple coagulation factor deficiency protein 2 contains the ability to support stem cell self-renewal. FASEB J. 2013 Aug;27(8):3298-305. 14.Chen Y#, Niu Y#, Yang S, He X, Ji S, Si W, Tang X, Xie Y, Wang H, Lu Y, Zhou Q, Ji W*. The available time window for embryo transfer in the rhesus monkey (Macaca mulatta). Am J Primatol. 2012 Feb;74(2):165-73. 15.Chen Y, Wang Z, Xie Y, Guo X, Tang X, Wang S, Yang S, Chen K, Niu Y, Ji W*. Folic acid deficiency inhibits neural rosette formation and neuronal differentiation from rhesus monkey embryonic stem cells. J Neurosci Res. 2012 Jul;90(7):1382-91. 16.Chen Y, Niu Y*, Ji W*. Transgenic nonhuman primate models for human diseases: approaches and contributing factors. J Genet Genomics. 2012 Jun 20;39(6):247-51. 17.Zhang Y, Zhang Y, Shi J, Zhang H, Cao Z, Gao X, Ren W, Ning Y, Ning L, Cao Y, Chen Y, Ji W, Chen ZJ, Chen Q*, Duan E*. Identification and characterization of an ancient class of small RNAs enriched in serum associating with active infection. J Mol Cell Biol. 2014 Apr;6(2):172-4. 18.Niu Y, Yu Y, Bernat A, Yang S, He X, Guo X, Chen D, Chen Y, Ji S, Si W, Lu Y, Tan T, Wei Q, Wang H, Shi L, Guan J, Zhu X, Afanassieff M, Savatier P, Zhang K, Zhou Q, Ji W*. Transgenic rhesus monkeys produced by gene transfer into early-cleavage-stage embryos using a simian immunodeficiency virus-based vector. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17663-7. 19.Hu Z, Li T, Zhang X, Chen Y. Hepatocyte growth factor enhances the generation of high-purity oligodendrocytes from human embryonic stem cells. Differentiation. 2009 Sep-Oct;78(2-3):177-84. 20.Wang S, Shen Y, Yuan X, Chen K, Guo X, Chen Y, Niu Y, Li J, Xu RH, Yan X, Zhou Q, Ji W*. Dissecting signaling pathways that govern self-renewal of rabbit embryonic stem cells. J Biol Chem. 2008 Dec 19;283(51):35929-40.
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