个人简介
教育经历：
2004/9-2009/7，军事医学科学院，放射与辐射医学研究所，博士
2000/9-2004/7，华中师范大学，生命科学学院，学士
工作经历：
2014/6-至今，苏州大学，医学部放射医学与防护学院，副教授
2012/5-2014/1，美国德州大学西南医学中心，放射肿瘤系，博士后
2011/8-2012/4，美国凯斯西储大学，血液肿瘤系，博士后
2009/12-2011/7，军事医学科学院，放射与辐射医学研究所，博士后
近期论文
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1) Li M*, Li S*, Liu B*, Gu MM, Zou S, Xiao BB, Yu L, Ding WQ, Zhou PK, Zhou J#, Shang ZF#. PIG3 promotes NSCLC cell mitotic progression and is associated with poor prognosis of NSCLC patients. J Exp Clin Cancer Res. 2017; 36(1):39.
2) Tian X*, Xiao BB*, Wu A, Yu L, Zhou J, Wang Y, Wang N, Guan H#, Shang ZF#. Hydroxylated-graphene quantum dots induce cells senescence in both p53-dependent and -independent manner. Toxicol Res. 2016; 5:1639-48
3) Zou LH, Shang ZF#, Tan Wei, Liu XD, Xu QZ, Song M, Wang Y, Guan H, Zhang SM, Yu L, Zhong CG, Zhou PK#. TNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1. Oncotarget. 2015; 6(9):7011-22.
4) Shang ZF*, Wei Q*, Yu L*, Huang F, Xiao BB, Wang H, Song M, Wang L, Zhou J, Wang J#, Li S#. Suppression of PC-1/PrLZ sensitizes prostate cancer cells to ionizing radiation by attenuating DNA damage repair and inducing autophagic cell death. Oncotarget. 2016; 7(38):62340-51.
5) Shang ZF*, Tan W*, Liu XD*, Yu L, Li B, Li M, Song M, Wang Y, Xiao BB, Zhong CG, Guan H#, Zhou PK#. DNA-PKcs Negatively Regulates Cyclin B1 Protein Stability through Facilitating Its Ubiquitination Mediated by Cdh1-APC/C Pathway. Int J Biol Sci. 2015; 11(9):1026-35.
6) Shang Z, Yu L, Lin YF, Matsunaga S, Shen CY, Chen BP#. DNA-PKcs activates the Chk2-Brca1 pathway during mitosis to ensure chromosomal stability. Oncogenesis. 2014; 3:e85.
7) Shang ZF*, Yu L*, Li B*, Tu WZ, Wang Y, Liu XD, Guan H, Huang B, Rang WQ, Zhou PK#. 4E-BP1 participates in maintaining spindle integrity and genomic stability via interacting with PLK1. Cell Cycle. 2012; 11(18):3463-71.
8) Shang ZF*, Huang B*, Xu QZ, Zhang SM, Fan R, Liu XD, Wang Y, Zhou PK#. Inactivation of DNA-dependent protein kinase leads to spindle disruption and mitotic catastrophe with attenuated checkpoint protein 2 Phosphorylation in response to DNA damage. Cancer Res. 2010; 70(9):3657-66.
9) Yu L*, Shang ZF*, Abdisalaam S, Lee KJ, Gupta A, Hsieh JT, Asaithamby A, Chen BP#, Saha D#. Tumor suppressor protein DAB2IP participates in chromosomal stability maintenance through activating spindle assembly checkpoint and stabilizing kinetochore-microtubule attachments. Nucleic Acids Res. 2016; 44(18):8842-54.
10) Zou S*, Shang ZF*, Liu B, Zhang S, Wu J#, Huang M#, Ding WQ, Zhou J#. DNA polymerase iota (Pol ι) promotes invasion and metastasis of esophageal squamous cell carcinoma. Oncotarget. 2016; 7(22):32274-85.
11) Yu L*, Shang ZF*, Wang J, Wang H, Huang F, Zhang Z, Wang Y, Zhou J#, Li S#. PC-1/PrLZ confers resistance to rapamycin in prostate cancer cells through increased 4E-BP1 stability. Oncotarget. 2015; 6(24):20356-69.
12) Yu L*, Shang ZF*, Hsu FM, Zhang Z, Tumati V, Lin YF, Chen BP, Saha D#. NSCLC cells demonstrate differential mode of cell death in response to the combined treatment of radiation and a DNA-PKcs inhibitor. Oncotarget. 2015; 6(6):3848-60.
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