个人简介
教育经历
2007-2010,香港城市大学,化学生物学,博士
2002-2005,厦门大学,有机化学,硕士
1998-2002,南昌大学,化学,学士
工作经历
2013-至今,苏州大学,放射医学与防护学院,副教授
2010-2013,香港城市大学,生物与化学系,博士后/高级研究员
2006-2007,香港城市大学,生物与化学系,助理研究员
2005-2006,上海无锡药明康德药物公司,有机合成研究员
研究领域
1. 光治疗纳米药物
2. 同位素标记纳米药物及其分子影像应用
近期论文
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1. S. Ye, J. Rao, S. Qiu, J. Zhao, H. He*, Z. Yan, T. Yang, Y. Deng, H. Ke, H. Yang, Y. Zhao, Z. Guo,* H. Chen*. Rational design of conjugated photosensitizers with controllable photoconversion for dually cooperative phototherapy. Adv Mater. 2018, DOI: 10.1002/adma.201801216.
2. H. He, S. Ji, Y. He, A. Zhu, Y. Zou, Y. Deng, H. Ke, H. Yang, Y. Zhao,* Z. Guo,* H. Chen*. Photoconversion-tunable fluorophore vesicles for wavelength-dependent photo-induced cancer therapy. Adv Mater. 2017, 1606690.
3. Z. Guo, Y. Zou, H. He, J. Rao, S. Ji, X. Cui, H. Ke, Y. Deng, H. Yong, C. Chen, Y. Zhao, H. Chen*. Bifunctional platinated nanoparticles for photo-Induced tumor ablation. Adv Mater. 2016, 28, 10155-10164.
4. J. Li, X. He, Y. Zou, D. Chen, L. Yang, J. Rao, H. Chen, M. C. W. Chan, L. Li, Z. Guo,* L. W. Zhang,* C. Chen, Mitochondria-targeted platinum(II) complex: dual inhibitory activities on cell proliferation and migration/invasion via b-Catenin Pathway. Metallomics, 2017, 9, 726-733.
5. C. Shen, F. Yu, W.-K. Chu, J. Xiang,* P. Tan, Y. Luo, H. Feng, Z.-Q. Guo,* C.-F. Leung,* and T.-C. Lau, Synthesis, structures and photophysical properties of luminescent cyanoruthenate(II) complexes with hydroxylated bipyridine and phenanthroline ligands. RSC Advance. 2016, 6, 87389-87399.
6. F. Yu, C. Shen, T. Zheng, W.-K. Chu, J. Xiang,* Y. Luo, C.-C. Ko, Z.-Q. Guo,* and T.-C. Lau. Acid-base behaviours in absorption and emission spectra of ruthenium(II) complexes with hydroxyl-substituted bipyridine and phenanthroline ligands. Eur J Inorg Chem. 2016, 2016, 3641-3648.
7. Z. Guo, W.-L. Tong, M. C. W. Chan. Luminescent oligo(ethylene glycol)-functionalized cyclometalated platinum(II) complexes: cellular characterization and mitochondria-specific localization. Chem Commun. 2014, 50, 1711-1714.
8. Z. Guo, S.-M. Yiu, M. C. W. Chan, Shape-persistent (Pt-salphen)2 phosphorescent coordination frameworks: structural insights and selective perturbations. Chem Eur J. 2013, 19, 8937-8947.
9. Z. Guo, M. C. W. Chan. Shape-persistent binuclear cyclometalated Pt(II) luminophores: Pushing π-mediated excimeric fluid emissions into the NIR region and ion-induced perturbations. Chem Eur J. 2009, 15, 12585-12588.
10. Z. Guo, W.-L. Tong, M. C. W. Chan. Axially rotating (Pt-salphen)2 phosphorescent coordination frameworks. Chem Commun. 2009, 6189-6191.