王洪枫 - 苏州大学 - 医学部药学院

个人简介

学习经历 2004-2009 中国科学技术大学神经生物学博士 2000-2004 中国科学技术大学生物科学学士科研经历 2013-至今副教授苏州大学药学院 2012-2013 Research Associate 耶鲁大学医学院合作导师: Angus Nairn 2011-2013 博士后苏州大学药学院合作导师：王光辉 2009-2011 博士后中国科学技术大学生命科学学院合作导师：王光辉

研究领域

1. 神经退行性疾病发病的分子机制 2. 泛素相关蛋白在蛋白质和线粒体质量控制中的作用机制

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Mao J, Xia Q, Liu C, Ying Z, Wang H* and Wang G* (2017) A critical role of Hrd1 in the regulation of optineurin degradation and aggresome formation. Hum Mol Genet.26(10):1877-1889 (*Corresponding author) 2. Zhang Z1, Wang H1, Ding Q1, Xing Y1, Xu D1, Xu Z, Zhou T, Qian B, Ji C, Pan X, Zhong A, Ying Z*, Zhou C*, Shi M* (2017). The tumor suppressor p53 regulates autophagosomal and lysosomal biogenesis in lung cancer cells by targeting transcription factor EB. Biomed Pharmacother. 89：1055-1060 (1co-first author) 3. Ying Z, Xia Q, Hao Z, Xu D, Wang M, Wang H* and Wang G* (2016) TARDBP/TDP-43 regulates autophagy in both MTORC1-dependent and MTORC1-independent manners.Autophagy12(4):707–8. 4. Zhou L1, Wang H1, Ren H, Hu Q, Ying Z* and Wang G* (2015). Bcl-2 Decreases the Affinity of SQSTM1/p62 to Poly-Ubiquitin Chains and Suppresses the Aggregation of Misfolded Protein in Neurodegenerative Disease.Mol Neurobiol.52(3):1180-9. (1co-first author) 5. Ying Z1, Wang H1, Wang G*(2013). The ubiquitin proteasome system as a potential target for the treatment ofneurodegenerative diseases.Curr Pharm Des. 19(18):3305-14. (1co-first author) 6. Wang H1, Ying Z1, Wang G*(2012). Ataxin-3 Regulates Aggresome Formation of Copper-Zinc Superoxide Dismutase (SOD1) by Editing K63-linked Polyubiquitin Chains. J Biol Chem. Aug 17;287(34):28576-85. (1co-first author) 7. Ying Z, Wang H*, Fan H, Wang G*(2011). The ER-associated degradation system regulates aggregation and degradation of mutant neuroserpin.J Biol Chem. Jun 10;286(23):20835-44.（*Corresponding author） 8. Wang H，Jia N，Fei E，Wang Z，Liu C，Zhang T，Fan J，Wu M，Chen L，Nukina N，Zhou J，Wang G (2007). p45, an ATPase subunit of the 19S proteasome, targets the polyglutamine disease protein ataxin-3 to the proteasome，J Neurochem. 101(6)：1651~1661