个人简介
学历背景:
1998.9-2002.6:原苏州医学院,药学专业,医学学士学位
2002.9-2005.6:免试推荐攻读硕士学位,药理学专业,医学硕士学位
2006.9-2010.6:药理学专业,医学博士学位
国外学习研究经历:
2014.6-2015.6:美国斯坦福大学,医学院,博士后
工作经历:
2005.8-2019.7:苏州大学医学部药学院药理学系,教师,副教授。
2019.7 至今: 苏州大学医学部药学院药理学系,教授。
近期论文
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(1)Wu Z#, Wang Y#, Lim J, Liu B, Li Y, Vartak R, Stankiewicz T, Montgomery S, Lu B. Ubiquitination of ABCE1 by NOT4 in response to mitochondrial damage links co-translational quality control to PINK1-directed mitophagy. Cell Metabolism. 2018; 28:1-15. (#Co-first author)
(2)Feng W#, Wang Y#, Liu ZQ, Zhang X, Han R, Miao YZ, Qin ZH. Microglia activation contributes to quinolinic acid-induced neuronal excitotoxicity through TNF-α. Apoptosis. 2017; 22(5):696-709. (#Co-first author)
(3)Dong XX, Wang YR, Qin S, Liang ZQ, Liu BH, Qin ZH, Wang Y*. p53 Mediates autophagy activation and mitochondria dysfunction in kainic acid-induced excitotoxicity in primary striatal neurons. Neuroscience. 2012; 207: 52-64. (*Corresponding author)
(4)Wang YR, Qin S, Liang ZQ, Han R, Wu JC, Qin ZH, Wang Y*. Cathepsin L plays a role in quinolinic acid-induced NF-κB activation and excitotoxicity in rats striatal neurons. PLoS One. 2013; 8(9):e75702. (*Corresponding author)
(5)Wang Y, Qin ZH. Coordination of autophagy with other cellular activities. Acta Pharmacol Sin. 2013; 34(5):585-594.
(6)Luo L, Lu AM, Wang Y, Hong A, Chen Y, Hu J, Li X, Qin ZH. Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats. Exp Gerontol. 2013; 48(4):427-436.
(7)Wang Y, Qin ZH. Molecular and cellular mechanisms of excitotoxic neuronal death. Apoptosis. 2010; 15:1382-1402.
(8)Wang Y, Dong XX, Cao Y, Liang ZQ, Han R, Wu JC, Gu ZL, Qin ZH. p53 induction contributes to excitotoxic neuronal death in rat striatum through apoptotic and autophagic mechanisms. Eur J Neurosci. 2009; 30:2258-2270.
(9)Wang Y, Han R, Liang ZQ, Wu JC, Zhang XD, Gu ZL, Qin ZH. An autophagic mechanism is involved in apoptotic death of rat striatal neurons induced by the non-N-methyl-D-aspartate receptor agonist kainic acid. Autophagy. 2008; 4:214-226.
(10)Wang Y, Gu ZL, Cao Y, Liang ZQ, Han R, Bennett MC, Qin ZH. Lysosomal enzyme cathepsin B is involved in kainic acid-induced excitotoxicity in rat striatum. Brain Res. 2006; 1071:245-249.
(11)Dong XX, Wang Y, Qin ZH. Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases. Acta Pharmacol Sin. 2009; 30:379-387.
(12)Zhang XD, Wang Y, Wang Y, Zhang X, Han R, Wu JC, Liang ZQ, Gu ZL, Han F, Fukunaga K, Qin ZH. p53 mediates mitochondria dysfunction-triggered autophagy activation and cell death in rat striatum. Autophagy. 2009; 5:339-350.