林芳 - 苏州大学 - 医学部药学院

个人简介

教育经历: 1991.9-1995.7：宁夏大学生命科学学院生物教育专业，获理学学士学位 1995.9-1998.7：南京农业大学自然资源与环境保护学院微生物系微生物专业，获理学硕士学位 1998.9—2002.6：中国药科大学药学院和中科院上海植物生理生态所分子遗传国家重点实验室，合作培养博士生，获得理学博士学位工作经历: 2003.7-2008.6：苏州大学基础医学系药理教研室讲师 2004.9-2007.3：苏州大学基础医学博士后流动站在职博士后 2008.7-：苏州大学医学部药学院药理系副教授 2012.1-2013.1：英国剑桥大学CIMR 访问学者（Prof. Rubinsztein's lab）

近期论文

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1) Lin F, Ghislat G#, Luo SQ, Renna M, Rubinsztein R C* .XIAP and CIAP 1 induce Beclin 1-dependent autophagy through NFκB activation. Hum Mol Gen，2015, 15;24(10):2899-913 #co-first author 2) Lu X, Liu WQ , Guo JJ , Bu HZ, Lin JH, Lin F*. Limitations of Microdialysis in Measuring Unbound Drug Concentrations in the Brain, Lat. Am. J. Pharm. 2014, 33 (10): 1609-17 3) Button RW, Lin F*, Ercolano E, Vincent JH, Hu B, Hanemann CO, Luo S. Artesunate induces necrotic cell death in schwannoma cells. Cell Death Dis. 2014 Oct 16. *co-first author 4) Jiang D, Chen K, Lu X, Gao HJ, Qin ZH, Lin F*. Exercise ameliorates the detrimental effect of chloroquine on skeletal muscles in mice via restoring autophagy flux. Acta Pharmacol Sin. 2014 . 35(1):135-42 5) Lin F, Qin ZH. Degradation of Misfolded Proteins by Autophagy: Is it a Strategy for Huntington's Disease Treatment? Journal of Huntington’s Disease. 2013. 2:149–157 6) Wu JC, Qi L, Wang Y, Kegel KB, Yoder J, Difigila M, Qin ZH, Lin F*. Regulation of N-terminal Huntingtin (Htt552) Accumulation by Beclin1. Acta Pharm sin, ;33(6):743-51 7) Chen LL, Wu JC, Qin ZH, Lin F*. Rapamycin prevents the mutant huntingtin-suppressed GLT-1expression in cultured astrocytes, Acta Pharm sin, 33(3):385-92. 8) Wang LH, Lin F, Wu JC, Qin ZH. High efficiency adenovirus- mediated expression of truncated N-terminal huntingtin fragment (htt552) in primary rat astrocytes. Acta Biochim Biophys Sin. 2009, 41(4):325-34. 9) Wu JC, Lin F, Qin Z. Sequestration of GAPDH to Aggregates Formed by Mutant Huntingtin. Acta Biochem Biophys Sin, 2007, 39(11): 885-890. 10) Li G, Lin F, Xue HW. Genome-wide analysis of the phospholipase D family in Oryza sativa and functional characterization of PLD beta 1 in seed germination.. Cell research, 2007, 17(10):881-94 11) Lin F, Wu JC, Wang Y, Qin ZH, Huntingtin cleavage induced by thrombin in vitro, Acta Biochimica et Biophysica Sinica, 2007,39(1): 15-18.