孙晓辉 - 苏州大学 - 医学部药学院

个人简介

学历背景： 1996.9-2000.7华中科技大学，精细化工，本科 2000.9-2003.7 华中科技大学，无机化学，硕士 2003.9-2007.7 华中科技大学，生物医学工程，博士国外研究经历： 2008.10-2010.8 英国牛津大学心血管医药系，博士后 2010.9-2013.2 美国华盛顿大学圣路易斯分校生物医学工程系，博士后 2013.2-2014.2 美国伊利诺伊大学医学院肿瘤生物与药理系，助理研究员

研究领域

(1) 离子通道的结构与功能 (2) 离子通道之间的相互作用 (3) 作用于离子通道的药物研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1) Sun X., Shi J., Delaloye K., Yang X., Yang H., Zhang G., Cui J. The interface between membrane-spanning and cytosolic domains in Ca2+-dependent K+ channels is involved inβ subunit modulation of gating. J. Neurosci. 2013, 33(27):11253-11261 2) Sun X., Zaydman M. A. and Cui J. Regulation of voltage-activated K+ channel gating by transmembrane βsubunits. Front. Pharmacol. 2012, 3:63 3) Xiao L.*, Xiong X.*, Sun X.*, Zhu Y., Yang H., Chen H., Gan L., Xu H., Yang X.Role of cellular uptake in the reversal of multidrug resistance by PEG-b-PLA polymeric micelles. Biomaterials. 2011, 32(22):5148-5157 4) Sun X., Ding J., Li H., Pan N., Gan L., Yang X., Xu H. Activation of large-conductance calcium-activated potassium channels by puerarin: the underlying mechanism of puerarin-mediated vasodilation. J. Pharmacol. Exp. Ther.2007, 323(1): 391-397 5) Xiong F.*, Sun X.*, Gan L., Yang X., Xu H. Puerarin protects rat pancreatic islets from damage by hydrogen peroxide. Eur. J. Pharmacol.2006, 529(1-3): 1–7 6) Liu B.,Sun X., Zhu Y., Gan L., Xu H., Yang X.Biphasic effects of H(2)O(2) on BK(Ca) channels. Free Radic.l Res.2010, 44(9):1004-1012 7) Lukacs V., Rives J.M., Sun X., Zakharian E., Rohacs T. Promiscuous activation of transient receptor potential vanilloid 1 (TRPV1) channels by negatively charged intracellular lipids: the key role of endogenous phosphoinositides in maintaining channel activity. J. Biol. Chem. 2013, 288(49): 35003-35013 8) Yang J., Yang H., Sun X., Delaloye K. Yang X., Moller A., Shi J.and Cui J. Interaction between residues in the Mg2+-binding site regulates BK channel activation.J. Gen. Physiol. 2013, 141(2):217-228 9) Liu B., Gan L., Sun X., Zhu Y., Tong Z., Xu H., Yang X.Enhancement of BK(Ca) channel activity induced by hydrogen peroxide: involvement of lipid phosphatase activity of PTEN. Biochim. Biophys. Acta.2009,1788(10):2174-2182 10) Wang W., Xiong W., Wan J., Sun X., Xu H., Yang X. The decrease of PAMAM dendrimer-induced cytotoxicity by PEGylation via attenuation of oxidative stress.Nanotechnology. 2009, 20(10):105103