邬珺超 - 苏州大学 - 医学部药学院

个人简介

学历背景： 1996.09－2000.07 苏州大学本科 2000.09－2003.07 苏州大学生物化学与分子生物学硕士生 2003.09－2004.09 苏州大学中药研究所 2004.09－2007.12 苏州大学药理学博士生, Ph.D 2008.01－至今　苏州大学药理学系工作经历： 2008.01－至今　苏州大学药理学系，助理研究员

研究领域

自噬/溶酶体途径参与神经退行性疾病致病及神经保护相关分子机制研究

近期论文

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1) Wu JC, Liang ZQ, Qin ZH. Quality Control System of the Endoplasmic Reticulum and Related Diseases. Acta Biochim Biophys Sin. 2006, 38: 219-226. 2) Wu JC, Lin F, Qin ZH. Sequestration of GAPDH to Aggregates Formed by Mutant Huntingtin. Acta Biochim Biophys Sin. 2007, 39: 885-890. 3) Lin F, Wu JC, Wang Y, Qin ZH. Huntingtin Cleavage Induced by Thrombin in Vitro. Acta Biochim Biophys Sin. 2007, 39: 15-18. （第二作者） 4) Xu XH, Hua Y, Zhang HL, Wu JC, Miao YZ, Han R, Gu ZL, Qin ZH. Greater Stress Protein Expression Enhanced by Combined Prostaglandin A1 and Lithium in a Rat Model of Focal Ischemia. Acta Pharmacol Sin, 2007, 28: 1097-1104. 5) He JK, YuSD, Zhu HJ, Wu JC, Qin ZH. Triptolide Inhibits NF-kB Activation and Reduces Injury of the Donor Lung Induced by Ischemia/reperfusion. Acta Pharmacologica Sin. 2007, 28: 1919-1923. 6) Wang Y, Han R, Liang ZQ, Wu JC, Zhang XD, Gu ZL, Qin ZH. An Autophagic Mechanism is Involved in Apoptotic Death of Rat Striatal Neurons Induced by the AMPA Receptor Agonist Kainic Acid. Autophagy. 2008, 4: 214-226. 7) Wang LH, Lin F, Wu JC, Qin ZH. High Efficiency Adenovirus-Mediated Expression of Truncated N-terminal Huntingtin Fragment (htt552) in Primary Rat Astrocytes. Acta Biochim Biophys Sin, 2009, 41: 325-334. 8) Zhang XD, Wang Y, Wu JC, Lin F, Han R, Han F, Fukunaga K, Qin ZH. Down-Regulation of Bcl-2 Enhances Autophagy Activation and Cell Death Induced by Mitochondrial Dysfunction in Rat Striatum. Journal of Neuroscience Research, 2009, 87: 3600-3610. 9) Yan Wang, Xiao-Xia Dong, Yi Cao, Zhong-Qin Liang, Rong Han, Jun-Chao Wu, Zhen-Lun Gu and Zhen-Hong Qin. p53 induction contributes to excitotoxic neuronal death inrat striatum through apoptotic and autophagic mechanisms. European Journal of Neuroscience, 2009, 30: 2258-2270. 10) Xing-Ding Zhang, Ye Wang, Yan Wang, Xuan Zhang, Rong Han, Jun-Chao Wu, Zhong-Qin Liang, Zhen-Lun Gu, Feng Han, Kohji Fukunaga and Zheng-Hong Qin. p53 mediates mitochondria dysfunction-triggered autophagy activation and cell death in rat striatum. Autophagy, 2009, 5(3): 339-350. 11) Yan-li LIU, Hai-ming LIN, Rong ZOU, Jun-chao WU, Rong HAN, Laurence N RAYMOND, Paul F REID, Zheng-hong QIN. Suppression of complete Freund’s adjuvant-induced adjuvant arthritis by cobratoxin. Acta Pharmacol Sin, 2009, 30(2): 219-227.