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[1] Du Y#, Liu Y#, Xu Y, Juan J, Zhang Z, Xu Z, Cao B, Wang Q, Zeng Y*, Mao X*. The transmembrane protein TMEPAI induces myeloma cell apoptosis by promoting degradation of the c-Maf transcription factor. J Biol Chem. 2018 Feb 21. pii: jbc.RA117.000972. doi: 10.1074/jbc.RA117.000972. [Epub ahead of print]
[2] Zhong Y, Meng F, Deng C, Mao X*, Zhong Z*.Targeted inhibition of human hematological cancers in vivo by doxorubicin encapsulated in smart lipoic acid-crosslinked hyaluronic acid nanoparticles.Drug Deliv. 2017 Nov;24(1):1482-1490.
[3] Wang S#, Juan J#, Zhang Z#, Du Y, Xu Y, Tong J, Cao B, Moran MF, Zeng Y*, Mao X*.Inhibition of the deubiquitinase USP5 leads to c-Maf protein degradation and myeloma cell apoptosis. Cell Death Disease, 2017 Sep 21;8(9):e3058. doi: 10.1038/cddis.2017.450.
[4] Wang S#, Li J#, Du Y, Xu Y, Wang Y, Zhang Z, Xu Z, Zeng Y, Mao X*, Cao B*. The Class I PI3K inhibitor S14161 induces autophagy in malignant blood cells by modulating the Beclin 1/Vps34 complex. J Pharmacol Sci. 2017;134:197-202. doi: 10.1016/j.jphs.2017.07.001.
[5] Xu Y#, Zhang Z#, Li J#, Tong J, Cao B, Taylor P, Tang X, Wu D, Moran M, Zeng Y, Mao X*. The ubiquitin conjugating enzyme UBE2O modulates c-Maf stability and induces myeloma cell apoptosis. J Hematol Oncol, 2017 Jul 3;10(1):132. doi: 10.1186/s13045-017-0499-7.
[6] Tang S, Shen H, Mao X, Dai H, Zhu X, Xue S, Ding Z, Lu J, Wu D, Tang X*. FLT3-ITD with DNMT3A R882 double mutation is a poor prognostic factor in Chinese patients with acute myeloid leukemia after chemotherapy or allogeneic hematopoietic stem cell transplantation. Int J Hematol. 2017 Jun 14. doi: 10.1007/s12185-017-2256-7.
[7] Xu Z, Hao Y, Ren L, Zhang Z, Xu X, Cao B, Dai K, Zhu L, Fang Q*, Kong Y,* Mao X*. A novel STAT3 inhibitor negatively modulates platelet activation and aggregation. Acta Pharm Sina, 2017. Mar 6. doi: 10.1038/aps.2016.155.
[8] Mao H#, Du Y#, Zhang Z, Cao B, Zhao J, Zhou H*, Mao X*. Nitroxoline displays anti-myeloma activity by targeting the TRIM25/p53 axle. Anti-cancer Drugs, 2017; 28(4):376-383. doi: 10.1097/CAD.0000000000000466.
[9] Yang J, Tu Z, Xu X, Luo J, Yan X, Ran C, Mao X, Ding K, Qiao C*. Novel conjugates of endoperoxide and 4-anilinoquinazoline as potential anticancer agents. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1341-1345. doi: 10.1016/j.bmcl.2017.02.023
[10] Tong J, Cao B, Martyn GD, Krieger JR, Taylor P, Yates B, Sidhu SS, Li SS, Mao X, Moran MF*. Protein-phosphotyrosine proteome profiling by superbinder-SH2 domain affinity purification mass spectrometry, sSH2-AP-MS. Proteomics. 2017 Mar;17(6). doi: 10.1002/pmic.201600360.
[11] Zeng Y#,*, Xu X#, Wang S, Zhang Z, Liu Y, Han K, Cao B, Mao X*. Ring finger protein 6 promotes breast cancer cell proliferation by stabilizing estrogen receptor alpha. Oncotarget. 2017 Feb 16. doi: 10.18632/oncotarget.15384.
[12] Xu X, Han K, Zhu J, Mao H, Lin X, Zhang Z, Cao B, Zeng Y*, Mao X*. An inhibitor of cholesterol absorption displays anti-myeloma activity by targeting the JAK2-STAT3 signaling pathway. Oncotarget. 2016 Sep 26. doi: 10.18632/oncotarget.12265
[13] Xu X#, Han K#, Tang X#, Zeng Y, Lin X, Zhao Y, Zhang Z, Cao B, Wu D, Mao X*. The ring finger protein RNF6 induces leukemia cell proliferation as a direct target of pre-B-cell leukemia homeobox 1. J Biol Chem. 2016;291(18):9617-28.
[14] Mao H#, Wang M#, Cao B, Zhou H, Zhang Z*, Mao X*. Interferon-stimulated gene 15 induces cancer cell death by suppressing the NF-κB signaling pathway. Oncotarget. 2016 Sep 21. doi: 10.18632/oncotarget.12160.
[15] Zhang Z, Tong J, Tang X, Juan J, Cao B, Hurren R, Chen G, Taylor P, Xu X, Shi C, Du J, Hou J, Wang G, WuD, Stewart A, Schimmer A, Moran M, Mao X*.The ubiquitin ligase HERC4 mediates c-Maf ubiquitination and delays the growth of multiple myeloma xenografts in nude mice. Blood, 2016;127(13):1676-86. pii: blood-2015-07-658203.
[16] Zhang Z#, Mao H#, Du X#, Zhu J, Xu Y, Wang S, Xu X, Ji P, Yu Y, Cao B, Han K, Hou T, Xu Z, Kong Y, Jiang G, Tang T, Qiao C, Mao X*. A novel small molecule agent displays potent anti-myeloma activity by inhibiting the JAK2-STAT3 signaling pathway. Oncotarget, 2016. doi: 10.18632/oncotarget.6974.
[17] Yuan N, Song L, Zhang S, Lin W, Cao Y, Xu F, Fang Y, Wang Z, Zhang H, Li X, Wang Z, Cai J, Wang J, Zhang Y, Mao X, Zhao W, Hu S, Chen S, Wang J. Bafilomycin A1 targets both autophagy and apoptosis pathways in pediatric B-cell acute lymphoblastic leukemia. Haematologica. 2015 Mar;100(3):345-56.
[18] Ji P, Xu X, Ma S, Fan J, Zhou Q, Mao X*, Qiao C*. Novel 2-Carbonylbenzo[b]thiophene 1,1-Dioxide Derivatives as Potent Inhibitors of STAT3 Signaling Pathway. ACS Med Chem Lett. 2015;6:1010-4.
[19] Han K, Xu X, Xu Z, Chen G, Zeng Y, Zhang Z, Cao B, Kong Y, Tang X, Mao X*. SC06, a novel small molecule compound, displays preclinical activity against multiple myeloma by disrupting the mTOR signaling pathway. Sci Rep. 2015;5:12809.
[20] Juan J#, Cheng L*, Shi M#, Liu Z, Mao X*. Poly-(allylamine hydrochloride)-coated but not poly(acrylic acid)-coated upconversion nanoparticles induce autophagy and apoptosis in human blood cancer cells. J Mater Chem B, 2015;3:5769-5776.
[21] Zhu J, Hou T*, Mao X*. Discovery of selective phosphatidylinositol 3-kinase inhibitors to treat hematological malignancies. Drug Discovery Today. 2015; 20:988-94.
[22] Zhu J#, Wang M#, Yu Y, Qi H, Han K, Tang J, Zhang Z, Zeng Y, Cao B, Qiao C, Zhang H, Hou T*, Mao X*. A novel PI3K inhibitor PIK-C98 displays potent preclinical activity against multiple myeloma. Oncotarget.2015;6:185-95.
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