个人简介
教育经历:
2013/06-2016/06,南开大学化学学院高分子化学研究所,高分子化学与物理专业,理学博士
2010/06-2013/06,南开大学化学学院元素有机化学研究所,有机化学专业,理学硕士
2006/09-2010/06,四川大学,化学学院化学系,化学专业,理学学士
工作经历:
2016/06-2019/06,荷兰格罗宁根大学医学中心,生物医学工程系,博士后
2019/07-至今,苏州大学,功能纳米与软物质研究院,副研究员
研究领域
1.氨基酸NCA的可控聚合以及聚多肽的高性能化;
2.二级结构可调控的聚多肽及其在药物递送方面的应用;
3.纳米仿生结构的自组装构筑与多功能化
近期论文
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Liu, Y.; Shi, L.; Su, L.; van der Mei, H. C.; Jutte, P. C.; Ren, Y.; Busscher, H. J., Nanotechnology-Based Antimicrobials and Delivery Systems for Biofilm-Infection Control. Chem. Soc. Rev. 2019, 48(2), 428–446. (Q1, IF: 40.443)
Liu, Y.; van der Mei, H. C.; Zhao, B.; Zhai, Y.; Cheng, T.; Li, Y.; Zhang, Z.; Busscher, H. J.; Ren, Y.; Shi, L., Eradication of Multidrug-Resistant Staphylococcal Infections by Light-Activatable Micellar Nanocarriers in a Murine Model. Adv. Funct. Mater. 2017, 27, 1701974. (Q1, IF: 15.621)
Liu, Y.; Busscher, H. J.; Zhao, B.; Li, Y.; Zhang, Z.; van der Mei, H. C.; Ren, Y.; Shi, L., Surface-Adaptive, Antimicrobially Loaded, Micellar Nanocarriers with Enhanced Penetration and Killing Efficiency in Staphylococcal Biofilms. ACS Nano 2016, 10 (4), 4779-4789.
Liu, Y.; Ren, Y.; Li, Y.; Su, L.; Zhang, Y.; Huang, F.; Liu, J.; Liu, J.; van Kooten, T. G.; An, Y.; Shi, L.; van der Mei, H. C.; Busscher, H. J., Nanocarriers with Conjugated Antimicrobials to Eradicate Pathogenic Biofilms Evaluated in Murine in Vivo and Human ex Vivo Infection Models. Acta Biomater. 2018, 79, 331–343.
Li, Y.; Hu, J.; Liu, X.; Liu, Y.;* Lv, S.; Dang, J.; Ji, Y.;* He, J.; Yin, L. C.,* Photodynamic Therapy-Triggered On-Demand Drug Release from ROS-Responsive Core-Cross-Linked Micelles toward Synergistic Anti-Cancer Treatment. Nano Res. 2019, 12(5), 999–1008. (co-corresponding author)
Liu, Y.; Li, Y.; Keskin, D. Shi, L., Poly(β-Amino Esters): Synthesis, Formulations, and Their Biomedical Applications. Adv. Healthc. Mater. 2019, 8(2), 1801359.
Li, Y.†; Liu, Y.†; Ma, R.; Xu, Y.; Zhang, Y.; Li, B.; An, Y.; Shi, L., A G-Quadruplex Hydrogel via Multicomponent Self-Assembly: Formation and Zero-Order Controlled Release. ACS Appl. Mater. Interfaces 2017, 9 (15), 13056–13067. († equal contribution)
Liang, Q. J.; Li, F. F.; Li, Y. J.; Liu, Y.;* Lan, M.; Wu, S. H.; Wu, X. J.; Ji, Y.;* Zhang, R. J.; Yin, L. C.,* Self-Assisted Membrane- Penetrating Helical Polypeptides Mediate Anti-Inflammatory RNAi against Myocardial Ischemic Reperfusion (IR) Injury. Biomater Sci.10.1039/C9BM00719A. (co-corresponding author)
Zhu, R. Y.; He, H.; Liu, Y.;* Cao, D. S.; Yan, J.; Duan, S. Z.; Chen, Y. B.; Yin, L. C.,* Cancer-Selective Bioreductive Chemotherapy Mediated by Dual Hypoxia-Responsive Nanomedicine upon Photodynamic Therapy-Induced Hypoxia Aggravation. Biomacromolecules, 2019, 20, 2649-2656. (co-corresponding author)
Ye, H.; Zhou, Y.; Liu, X.; Chen, Y. B.;* Duan, S. Z.; Zhu, R. Y.; Liu, Y.;* Yin, L. C.,* Recent Advances on Reactive Oxygen Species (ROS)-Responsive Delivery and Diagnosis System. Biomacromolecules, 2019, 20, 2441-2463. (co-corresponding author)