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(1) Xiaodong Ding, Sandeep K. Barodi, Lisha Ma, Matthew S. Goldberg (2017) Fbxl18 targets LRRK2 for proteasomal degradation and attenuates cell toxicity. Neurobiology of Disease 98:122–136
(内容简介:利用酵母二元杂交技术首次鉴定到一个与LRRK2激酶有物理互作关系的泛素化连接酶基因Fbxl18,Co-IP技术确定这两个蛋白在动物细胞内具有特异的互作关系,同时Fbxl18能够介导LRRK2经过蛋白酶体途径进行降解,并且LRRK2的磷酸化是Fbxl18介导其降解的前提条件。由Fbxl18介导的LRRK2降解可以有效的抑制基因对细胞的毒害作用,从而使得Fbxl18和LRRK2成为药物作用靶点)
(2) Xuewei Song,Huizi Duanmu,Yang Yu,Chao Chen,Xiaoli Sun,Pinghui Zhu,Ranran Chen,Xiangbo Duan,Huiqing Li,Lei Cao,Zaib un Nisa,Qiang Li,Yanming Zhu, Xiaodong Ding (2017) GsJ11, identified by genome-wide analysis, facilitates alkaline tolerance in transgenic plants. Plant Cell Tissue and Organ Culture. doi:10.1007/s11240-017-1188-5
(内容简介: 根据野生大豆的转录组谱的数据,发现了一个分子伴侣基因GsJ11能够被盐碱所正调控,转基因植物对盐碱表现出一定的抗性)
(3)Lei Cao, Yang Yu, Huizi DuanMu, Chao Chen, Xiangbo Duan, Pinghui Zhu, Ranran Chen, Qiang Li, Yanming Zhu, Xiaodong Ding (2016). A novel Glycine soja homeodomain-leucine zipper (HD-Zip) I gene, Gshdz4, positively regulates bicarbonate tolerance and responds to osmotic stress in Arabidopsis. BMC Plant Biol. 16: 184.
(内容简介: 首次发现和报道了野生大豆GsHDZ4基因所具有的对碳酸钠碱性盐抗性方面的生理功能,为该基因在选育对盐碱有高抗性的农作物新品种提供了理论依据)
(4)Yang Yu, Ailin Liu, Xiangbo Duan, Sunting Wang, Xiaoli Sun, Huizi Duanmu, Dan Zhu, Chao Chen, Lei Cao, Jialei Xiao, Qiang Li, Zaib_un Nisa, Yanming Zhu, Xiaodong Ding (2016). GsERF6, an ethylene-responsive factor from Glycine soja, mediates the regulation of plant bicarbonate tolerance in Arabidopsis. Planta. 244: 681-98.
(内容简介: 鉴定和发现了野生大豆基因GsERF6在植物中对盐碱胁迫的反应,并在拟南芥中表现出耐盐碱的生理功能)
(5)Xiaodong Ding, Tadashi Matsumoto, Patrizia Gena, Chengwei Liu, Marialuisa Pellegrini-Calace, Shihua Zhong, Xiaoli Sun, Yanming Zhu, Maki Katsuhara, Ikuko Iwasaki, Yoshichika Kitagawa, Giuseppe Calamita (2013). Water and CO2 permeability of SsAqpZ, the cyanobacterium Synechococcus sp. PCC7942 aquaporin. Biol Cell. 105: 118-28
(内容简介: 首次以光合细菌PCC7942为模型,证明水通道蛋白具有二氧化碳气体通透特性,该菌系的水通道基因SsAqpZ的敲除显著抑制了细菌的二氧化碳的吸收和光合作用效率,为进一步研究植物的相关蛋白,提高植物光合作用提供了科学依据)
(6)Xiaodong Ding, Todd Richter, Mei Chen, Hiroaki Fujii, Mingtang Xie, Xianwu Zheng, Siddhartha Kanrar, Rebecca A. Stevenson, Christopher Dardick, Ying Li, Hao Jiang, Yan Zhang, Fahong Yu, Lihuang Zhu, William G. Farmerie, Michael Gribskov, Jian-Kang Zhu, Michael E. Fromm, Pamela C. Ronald, and Wen-Yuan Song (2009). A rice protein-kinase interaction network. Plant Physiology 149: 1478-1492.
(内容简介: 克隆了300条水稻蛋白激酶全长基因,运用高通量酵母二元杂交技术筛选了水稻cDNA文库,获得了500百多互作蛋白,构建了首个大规模水稻蛋白激酶-蛋白质互作数据库。)
(7)Xiaodong Ding, Matthew Goldberg (2009). Regulation of LRRK2 Stability by the E3 Ubiquitin Ligase CHIP. PLOS One 4: e5949
(内容简介: 利用酵母二元杂交技术筛选小鼠大脑cDNA文库,获得了帕金森症相关基因LRRK2的互作蛋白CHIP,生物化学研究表明CHIP具有E3泛素连接酶活性,并引导LRRK2到蛋白酶体消化分解,从而减轻病变LRRK2对细胞的毒害性)
(8)Xiaodong Ding, Yan Zhang, Wen-Yuan Song. (2007). Use of Rolling Circle Amplification for Large-scale Protein-Protein Interaction Studies. Methods in Molecular Biology, published by Humana Press, pp: 85-98.
(内容简介: 系统描述了经过改进的基于Rolling Circle Amplification高通量大规模酵母二元杂交技术流程)
(9)Xiaodong Ding, Gina Cory, and Wen-Yuan Song. (2004). A high-throughput system to verify candidate interactors from yeast two-hybrid screening using rolling circle amplification. Analytical Biochemistry. 331: 195-197.
(内容简介: 利用Rolling Circle Amplification成功地直接从酵母细胞中扩增出了环形质粒,并且扩增的质粒可以重新转入酵母中表达,从而为发明高通量酵母二元杂交提供了关键技术)
(10)Xiaodong Ding, Ikuko Iwasaki, Yoshichika Kitagawa. (2004). Overexpression of a lily PIP1 gene in tobacco increased the osmotic water permeability in the leaf cells. Plant Cell Environ. 27: 177–186.
(内容简介: 百合花瓣中的水通道蛋白基因PIP1,在叶片原生质体中具有水孔蛋白的生化和生理活性,在烟草中过量表达可以显著提高植物的抗旱和干物质积累)
(11)Xiaodong Ding, Anita K. Snyder, Regina Shaw, William G. Farmerie, and Wen-Yuan Song. (2003). Direct retransformation of yeast with plasmid DNA isolated from single yeast colonies using rolling circle amplification. Biotechniques. 35: 774-779.
(12)Xiaodong Ding#, David Kozono#, Ikuko Iwasaki, Xianying Meng, Yoichi Kamagata, Peter Agre and Yoshichika Kitagawa. (2003). Functional expression and characterization of a novel archeael aquaporin, AqpM from Methanothermobacter Marburgensis. J. Biol. Chem. 278: 10649–10656.
(13)Xiaodong Ding, Yoshichika Kitagawa. (2001). Rapid amplification of water channel-likegene and its flanking sequences from Methanobacterium thermoautotrophicum Marburg genome with single primer PCR strategy. J. Biosci. Bioeng. 92: 488-491. (IF: 2.31)
(14)Chengwei Liu, Tatsuya Fukumoto, Tadashi Matsumoto, Patrizia Gena, Giuseppe Calamita, Tomoyuki Kaneko, Maki Katsuhara, Shihua Zhong, Xiaoli Sun, Yanming Zhu, Xiaodong Ding, Ikuko Iwasaki, Yoshichika Kitagawa (2013). Aquaporin OsPIP1;1 promotes rice salt resistance and seed germination. Plant Physiol. Biochem. 63:151-158
(15)Yoshichika Kitagawa, Chengwei Liu, Xiaodong Ding (2011). The influence of natural mineral water on aquaporin water permeability and human natural killer cell activity. Biochem. Biophys. Res. Commun. 409:40-45.)
(16)Xiaoli Sun, Hua Cai, Yong Li, Xi Bai, Wei Ji, Xiaodong Ding, Yanming Zhu (2012). The Arabidopsis AtbZIP1 transcription factor is a positive regulator of plant tolerance to salt, osmotic and drought stress. J. Plant Research 125(3):429-38
(17)Kuldip D. Dave, Shehan De Silva, Niketa P. Sheth, Sylvie Ramboz, Melissa J. Beck, Changyu Quang, Robert C. Switzer III, Syed Ahmad, Susan M. Sunkin, Dan Walker, Xiaoxia Cui, Daniel A. Fisher, Aaron M. McCoy, Kevin Gamber, Xiaodong Ding, Matthew S. Goldberg, Stanley A. Benkovic, Meredith Haupt, Marco A.S. Baptista, Brian K. Fiske, Todd B. Sherer, Mark A. (2014). Phenotypic characterization of recessive gene knockout rat models of Parkinson’s disease. Neurobiology of Disease. pii: S0969-9961(14)00173-9.
(18)Xiao Luo, Xiaoli Sun, Baohui Liu, Dan Zhu, Xi Bai, Hua Cai, Wei Ji, Lei Cao, Jing Wu, Mingchao Wang, Xiaodong Ding, Yanming Zhu (2013). Ectopic Expression of a WRKY Homolog from Glycine soja Alters Flowering Time in Arabidopsis. Plos One 8: e73295.
(19) Xiao-Li Sun, Qing-Yue Yu, Li-Li Tang, Wei Ji, Xi Bai, Hua Cai, Xiao-Fei Liu, Xiao-Dong Ding, Yan-Ming Zhu (2013). GsSRK, a G-type lectin S-receptor-like serine/threonine protein kinase, is a positive regulator of plant tolerance to salt stress. J Plant Physiol. 170 (5): 505-515.
(20)De-Kang Lv, Xi Bai, Yong Li, Xiao-Dong Ding, Ying Ge, Hua Cai, Wei Ji, Nalahu Wu, Yan-Ming Zhu (2010). Profiling of cold-stress-responsive miRNAs in rice by microarrays. Gene 459(1-2):39-47."