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个人简介

肖亚中,男,博士,二级教授,博士生导师。1984年本科毕业于安徽大学生物系生化微生物专业,获学士学位。1994年在中国科技大学获硕士学位。1997-1998年Hong Kong University of Science & Technology生化系任访问学者。2002年毕业于中国科技大学生物化学与分子生物学专业,获博士学位。2005-2006年在美国Florida International University从事博士后研究。 学术获奖: 肖亚中,方泽民等,海洋微生物来源优质酶蛋白发现、催化机制及理性改造,安徽省科学技术奖,二等奖 肖亚中,洪宇植等,漆酶的优质资源发现与高效表达调控机制研究,安徽省科学技术奖,二等奖

研究领域

基因表达调控的分子机制;生物催化;微生物通讯。研究领域包括基因工程、酶与酶工程等。

近期论文

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Li J, Xie YN, Wang R, Fang ZM, Fang W, Zhang XC*, Xiao YZ*. (2018) Mechanism of salt induced activity enhancement of a marine derived laccase, Lac15. European Biophysics Journal 47:225-236 Chang F, Zhang XB, Pan Y, Lu YX, Fang W, Fang ZM*, Xiao YZ*. (2017) Light induced expression of β-glucosidase in Escherichia coli with autolysis of cell. BMC Biotechnology 17:74-84 He C, Li J, Li W, Xue Y, Fang ZM, Fang W, Zhang XC, Wang XT, Xiao YZ*. (2016) Structures of PspAG97A α-glucoside hydrolase reveal a novel mechanism for chloride induced activation. Journal of Structural Biology 196: 426-36 Fang W, Yang Y, Zhang XX, Yin Q, Zhang XC, Wang XT, Fang ZM*, Xiao YZ*. (2016) Improve ethanol tolerance of β-glucosidase Bgl1A by semi-rational engineering for the hydrolysis of soybean isoflavone glycosides. Journal of Biotechnology 227: 64-71 Yang Y, Zhang XX, Fang W, FangZM, Wang XT, ZhangXC*, Xiao YZ*. (2015) A mechanism of glucose tolerance and stimulation of GH1 β-glucosidases. Scientific Reports 5:17296 Fang W, Song R, Zhang XB, Zhang XC, Fang ZM*, Xiao YZ*. (2014) A novel β-glucosidase from Gongronella sp.W5 with high productivity in the hydrolysis of soybean isoflavone glycosides. Journal of Agricultural and Food Chemistry 62: 11688 Fang W, Fang ZM, Zhou P, Chang F, Hong YZ, Zhang XC, Peng H, Xiao YZ*. (2012) Evidence for lignin oxidation by the giant panda fecal microbiome. PLoS ONE10.1371/journal.pone.0050312 Ji L, Shen Y, Xu LL, Peng BG, Xiao YZ*, Bao XM*. (2011) Enhanced resistance of Saccharomyces cerevisiae to vanillin by expression of lacA from Trametes sp. AH28-2. Bioresource Technology 102: 8105 Fang ZM, Li TL, Wang Q, Zhang XC, Peng H, Fang W, Hong YZ, Ge HH, Xiao YZ*. (2011) A bacterial laccase from marine microbial metagenome exhibiting chloride tolerance and dye decolorization ability. Applied Microbiology and Biotechnology (2011) 89:1103 Wei F, Hong YZ, Xiao YZ*, Liu JJ, Yuan J. (2010) Gongronella sp induces overproduction of laccase in Panus rudis. Journal of Basic Microbiology 50:1

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