个人简介
曹学君, 男, 教授, 博士,中共党员,华东理工大学生物工程学院,博士生导师。1996年博士毕业, 工作在华东理工大学生物反应器工程国家重实验室(生物工程系) 从事生物分离工程研究工作,并担任相应的教学工作。五次获得国家自然科学基金项目资助:“两水相体系交联酶相转移催化合成头孢IV (29873014,1999.1-2001.12)”、“光敏可再生两水相成相材料的研制”(20474016,2005.1-2007.12)、“多孔硅胶表面分子印迹吸附剂在超临界条件下的分离行为”(20676032,2007.1-2009.12)、“促溶离子提高反胶束萃取效率的机制与应用研究”(20976052,2010.1-2012.12)、“再生型两水相体系成相与分配的分子调控机制及其应用研究”(21376078,2014.1-2017.12)。主要参与“十一五”国家重大新药创制专项-生物技术新药中试放大及分离纯化技术平台项目(2009ZX09306-001,2009.1-2010.12)。牵头负责“十二五”863重大化工产品的先进生物制造重大项目-柠檬酸与葡萄糖酸的生物转化技术(2011AA02A213)。在国内外主要刊物上发表包括AIChE J、 J. Chromatography A、 Bioresource Technology 及J. Biotechnology在内的学术论文104篇,发明专利28项。主编《现代生物分离工程》教材, 负责并主讲的《生物分离工程》国家精品资源共享课程及教育部海外留学品牌英语课程。
教育经历
1993-1996 华东理工大学化学工程系博士
1990-1993 华东理工大学生化工程系硕士
1979-1982 河南开封医专药学系(现为河南大学药学院)
研究与工作经历
2000-2001 韩国仁荷大学校生物工程系博士后
1996-至今 华东理工大学生物反应器工程国家重点实验室,生化工程系
研究领域
1 重组蛋白质与天然活性成分的分离纯化
2 再生型两水相体系萃取与酶催化反应
3 生物分离材料的制备
近期论文
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1.Chengning Xu, Wenying Dong, Junfen Wan∗, Xuejun Cao*,Synthesis of thermo-responsive polymers recycling aqueoustwo-phase systems and phase formation mechanism with partition of -polylysine,Journal of Chromatography A, 2016,1472 :44–54.
2.Yueqian Zhang, Xuejun Cao*, Separation of cordycepin using surface molecular imprinting technology, Process Biochemistry, 2016, 51:517-527.
3.Sipeng Li, Zhaoyang Ding, Xuejun Cao*, Separation of transglutaminase by thermo-responsive affinity precipitation using L-thyroxin as ligand, SpringPlus, 2016 , 5:37-49.
4.Juan Xu, Le Wang, Xuejun Cao*,Polymer Supported Graphene-CdS Composite Catalyst with Enhanced Photocatalytic Hydrogen Production from Water Splitting under Visible Light,Chemical Engineering Journal,2016, 283 :816–825.
5.Jiali Liu, Xuejun Cao* Preparation of novel alkaline pH-responsive copolymers for the formation of recyclable aqueous two-phase systems and their application in the extraction of lincomycin,Journal of Separation Science,2016 ,39(3): 584-594.
6.Xiaomei Huang and Xuejun Cao*, Preparation of ursodeoxycholic acid from 7-ketone lithocholic acid by stereoselective electroreduction,Bioresources and Bioprocessing,2015,2:27.
7.Huiyun Hou, Xuejun Cao* , pH recycling aqueous two-phase systems applied in extraction of Maitake β-Glucan and mechanism analysis using Low-Field Nuclear Magnetic Resonance,Journal of Chromatography A,2015,1405:40–48.
8.Zhaoyang Ding, Sipeng Li, Xuejun Cao*, Microbial transglutaminase separation by pH-responsive affinity precipitation with Crocein Orange G as the ligand, Applied Biochemistry and Biotechnology ,2015, 177:253–266.
9.Zi Wang; Xuejun Cao*, Preparation of core-shell molecular imprinting polymer for lincomycin A and its application in chromatographic column, Process Biochemistry, 2015, 50(7):1136–1145
10.Juan Xu, Xuejun Cao*, Characterization and mechanism of MoS2/CdS composite photocatalyst used for hydrogen production from water splitting under visible light,Chemical Engineering Journal,2015 , 260:642-648.
11.Daisong Hou, Xuejun Cao∗,Synthesis of two thermo-responsive copolymers forming recyclableaqueous two-phase systems and its application in cefprozil partition,Journal of Chromatography A,2014,1349 30–36
12.Chaohui Zhu and Xuejun Cao*, Synthesis of Cefprozil Using Penicillin G Acylase in Recyclable Aqueous Two-phase Systems, Biotechnology and Bioprocess Engineering , 2014,19: 844-850.
13.Xiaolei Ma, Xuejun Cao*, Separation of ursodeoxycholic acid by silylation crystallization, Bioresources and Bioprocessing, 2014, 1:5.
14.Zhaoyang Ding, Sipeng Li, Xuejun Cao*, Separation of lysozyme from salted duck egg white by affinity precipitation using pH-responsive polymer with an L-thyroxin ligand,Separation and Purification Technology, 2014,138 :153–160.
15.Bo Yan, Xuejun Cao*, Phase diagram of novel recycling aqueous two-phase systems composed of two pH-response polymers: Experiment and modeling, Fluid Phase Equilibria, 2014, 364: 42–47.
16.Jingjing Liu,Xuejun Cao*, Biodegradation of Cellulose by β-glucosidase and Cellulase Immobilized on a pH-responsive Copolymer, Biotechnology and Bioprocess Engineering, 2014, 19: 829-837
17.Daisong Hou, Yanjie Li, Xuejun Cao*. Synthesis of two thermo-sensitive copolymers forming aqueous two-phase systems. Separation and Purification Technology, 2014,122 :217–224.
18.Xiangxi Yuan, Xiaolei Ma, and Xuejun Cao*, Preparation of ursodeoxycholic acid by direct electro-reduction of 7-ketolithocholic acid, Korean J. Chem. Eng., 2014, 31(7):1276-1280.
19.Tingting Yu, Xuejun Cao*, Effect of chaotropes on lipase back extraction recovery in the process of reverse micellar extraction, Applied Biochemistry and Biotechnology, 2014, 172(6):3287-3296.
20.Zhaoyang Ding, Kai Zheng, and Xuejun Cao* , Lipase Purification by Affinity Precipitation with a Thermo-responsive Polymer Immobilized Cibacron Blue F3GA Ligand, Biotechnology and Bioprocess Engineering, 2014, 19: 892-899.